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Adrian Newman-Tancredi

Adrian Newman-Tancredi

D-Index & Metrics

Neuroscience

D-Index
72
Citations
15092
World Ranking
2348
National Ranking
1112

Overview

Adrian Newman-Tancredi is affiliated with Neurolixis in the United States and has an extensive publication record primarily in the fields of neuroscience, biochemistry, genetics and molecular biology, and medicine. Their research spans several subfields including cellular and molecular neuroscience, molecular biology, pharmacology, neurology, and cognitive neuroscience.

The main research topics covered by Newman-Tancredi focus on neurotransmitter receptor influence on behavior, neuroscience and neuropharmacology research, receptor mechanisms and signaling, treatment of major depression, tryptophan and brain disorders, Parkinson's disease mechanisms and treatments, as well as neurological disorders and treatments.

Frequent publication venues for their research include Neuropharmacology, bioRxiv (Cold Spring Harbor Laboratory), Journal of Medicinal Chemistry, Translational Psychiatry, and Behavioural Brain Research.

Newman-Tancredi has collaborated extensively with several co-authors, notably:

  • Ronan Depoortère
  • Mark A. Varney
  • Luc Zimmer
  • Marcin Kołaczkowski
  • Mariusz Papp

Significant recent publications by Adrian Newman-Tancredi include:

  • "Translating biased agonists from molecules to medications: Serotonin 5-HT1A receptor functional selectivity for CNS disorders" (2021), Pharmacology & Therapeutics
  • "International Union of Basic and Clinical Pharmacology. CX. Classification of Receptors for 5-hydroxytryptamine; Pharmacology and Function" (2020), Pharmacological Reviews
  • "Perspectives for therapy of treatment-resistant depression" (2021), British Journal of Pharmacology
  • "The selective 5-HT1A receptor agonist, NLX-112, exerts anti-dyskinetic and anti-parkinsonian-like effects in MPTP-treated marmosets" (2020), Neuropharmacology
  • "The selective 5-HT1A receptor agonist, NLX-112, exerts anti-dyskinetic effects in MPTP-treated macaques" (2020), Parkinsonism & Related Disorders

Best Publications

  • The Novel Melatonin Agonist Agomelatine (S20098) Is an Antagonist at 5-Hydroxytryptamine2C Receptors, Blockade of Which Enhances the Activity of Frontocortical Dopaminergic and Adrenergic Pathways

    Mark J. Millan;Alain Gobert;Françoise Lejeune;Anne Dekeyne

  • Differential Actions of Antiparkinson Agents at Multiple Classes of Monoaminergic Receptor. I. A Multivariate Analysis of the Binding Profiles of 14 Drugs at 21 Native and Cloned Human Receptor Subtypes

    Mark J. Millan;Lisa Maiofiss;Didier Cussac;Valérie Audinot

  • Serotonin2C receptors tonically suppress the activity of mesocortical dopaminergic and adrenergic, but not serotonergic, pathways: A combined dialysis and electrophysiological analysis in the rat

    Alain Gobert;Jean‐Michel Rivet;Françoise Lejeune;Adrian Newman‐Tancredi

  • Simultaneous quantification of serotonin, dopamine and noradrenaline levels in single frontal cortex dialysates of freely-moving rats reveals a complex pattern of reciprocal auto- and heteroreceptor-mediated control of release

    A Gobert;J.-M Rivet;V Audinot;A Newman-Tancredi

  • Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a []GTPγS binding study

    Adrian Newman-Tancredi;Samantha Gavaudan;Caroline Conte;Christine Chaput

  • Agonist and antagonist actions of yohimbine as compared to fluparoxan at alpha(2)-adrenergic receptors (AR)s, serotonin (5-HT)(1A), 5-HT(1B), 5-HT(1D) and dopamine D(2) and D(3) receptors. Significance for the modulation of frontocortical monoaminergic transmission and depressive states.

    Mark J. Millan;Adrian Newman‐Tancredi;Valérie Audinot;Didier Cussac

  • 5-HT(1A) [corrected] receptors in mood and anxiety: recent insights into autoreceptor versus heteroreceptor function.

    Alvaro L. Garcia-Garcia;Adrian Newman-Tancredi;E. David Leonardo

  • Differential actions of antiparkinson agents at multiple classes of monoaminergic receptor. II. Agonist and antagonist properties at subtypes of dopamine D(2)-like receptor and alpha(1)/alpha(2)-adrenoceptor.

    Adrian Newman-Tancredi;Didier Cussac;Valérie Audinot;Jean-Paul Nicolas

  • International Union of Basic and Clinical Pharmacology. CX. Classification of Receptors for 5-hydroxytryptamine; Pharmacology and Function

    Nicholas M. Barnes;Gerard P. Ahern;Carine Becamel;Joël Bockaert

  • Mirtazapine enhances frontocortical dopaminergic and corticolimbic adrenergic, but not serotonergic, transmission by blockade of alpha2-adrenergic and serotonin2C receptors: a comparison with citalopram.

    M. J. Millan;A. Gobert;J. M. Rivet;A. Adhumeau-Auclair

  • Differential Actions of Antiparkinson Agents at Multiple Classes of Monoaminergic Receptor. III. Agonist and Antagonist Properties at Serotonin, 5-HT1 and 5-HT2, Receptor Subtypes

    Adrian Newman-Tancredi;Didier Cussac;Yann Quentric;Manuelle Touzard

  • S33005, a Novel Ligand at Both Serotonin and Norepinephrine Transporters: I. Receptor Binding, Electrophysiological, and Neurochemical Profile in Comparison with Venlafaxine, Reboxetine, Citalopram, and Clomipramine

    Mark J. Millan;Alain Gobert;Françoise Lejeune;Adrian Newman-Tancredi

  • Comparative pharmacology of antipsychotics possessing combined dopamine D2 and serotonin 5-HT1A receptor properties.

    Adrian Newman-Tancredi;Mark S. Kleven

  • Contrasting mechanisms of action and sensitivity to antipsychotics of phencyclidine versus amphetamine: importance of nucleus accumbens 5-HT2A sites for PCP-induced locomotion in the rat.

    M. J. Millan;M. Brocco;A. Gobert;F. Joly

  • A comparative in vitro and in vivo pharmacological characterization of the novel dopamine D3 receptor antagonists (+)-S 14297, nafadotride, GR 103,691 and U 99194.

    Valérie Audinot;Adrian Newman-Tancredi;Alain Gobert;Jean-Michel Rivet

  • Chronic restraint stress induces mechanical and cold allodynia, and enhances inflammatory pain in rat: Relevance to human stress-associated painful pathologies

    L. Bardin;N. Malfetes;A. Newman-Tancredi;R. Depoortère

  • Actions of alpha2 adrenoceptor ligands at alpha2A and 5-HT1A receptors: the antagonist, atipamezole, and the agonist, dexmedetomidine, are highly selective for alpha2A adrenoceptors.

    A Newman-Tancredi;J P Nicolas;V Audinot;S Gavaudan

  • S33084, a novel, potent, selective, and competitive antagonist at dopamine D(3)-receptors: I. Receptorial, electrophysiological and neurochemical profile compared with GR218,231 and L741,626.

    Mark J. Millan;Alain Gobert;Adrian Newman-Tancredi;Françoise Lejeune

  • Functional correlates of dopamine D3 receptor activation in the rat in vivo and their modulation by the selective antagonist, (+)-S 14297: 1. Activation of postsynaptic D3 receptors mediates hypothermia, whereas blockade of D2 receptors elicits prolactin secretion and catalepsy.

    M J Millan;J L Peglion;J Vian;J M Rivet

  • Clozapine is a partial agonist at cloned, human serotonin 5-HT1A receptors.

    A. Newman-Tancredi;C. Chaput;L. Verriele;M.J. Millan

  • Contrasting Contribution of 5-Hydroxytryptamine 1A Receptor Activation to Neurochemical Profile of Novel Antipsychotics: Frontocortical Dopamine and Hippocampal Serotonin Release in Rat Brain

    Marie-Bernadette Assié;Véronique Ravailhe;Valérie Faucillon;Adrian Newman-Tancredi

  • Levomilnacipran (F2695), a norepinephrine-preferring SNRI: profile in vitro and in models of depression and anxiety.

    A.L. Auclair;J.C. Martel;M.B. Assié;L. Bardin

Frequent Co-Authors

Nicolas Costes
Nicolas Costes Grenoble Alpes University
Pau Celada
Pau Celada Spanish National Research Council
Francesc Artigas
Francesc Artigas Spanish National Research Council
Umberto Spampinato
Umberto Spampinato University of Bordeaux
Sietse F. de Boer
Sietse F. de Boer University of Groningen
Mariusz Papp
Mariusz Papp Polish Academy of Sciences
Gilles Tamagnan
Gilles Tamagnan Yale University
Esther Berrocoso
Esther Berrocoso University of Cádiz
Paul Willner
Paul Willner Swansea University
Judith R. Homberg
Judith R. Homberg Radboud University

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