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Molecular Biology

D-Index
58
Citations
9769
World Ranking
2111
National Ranking
1047

Overview

Alain P. Gobert is affiliated with Vanderbilt University Medical Center in the United States and has contributed significantly to the fields of biochemistry, genetics, molecular biology, and medicine. Their research primarily focuses on molecular biology, surgery, immunology, biochemistry, and pharmacology, addressing several topics related to polyamine metabolism, Helicobacter pylori-associated gastroenterology, and cancer research.

The scientist has published extensively in several prominent venues. Frequent publication outlets include Gastroenterology, Oncogene, The Journal of Immunology, Gut Microbes, and SSRN Electronic Journal.

Key topics in their work cover:

  • Polyamine Metabolism and Applications
  • Helicobacter pylori-related gastroenterology studies
  • Gut microbiota and health
  • Eosinophilic Esophagitis
  • Amino Acid Enzymes and Metabolism
  • Cancer Research and Treatments
  • Probiotics and Fermented Foods

Frequent co-authors collaborating with Alain P. Gobert comprise Keith T. Wilson, Daniel P. Barry, Margaret M. Allaman, M. Blanca Piazuelo, and Kara M. McNamara.

Selected recent publications by Alain P. Gobert include:

  • Protective Role of Spermidine in Colitis and Colon Carcinogenesis, 2021, Gastroenterology
  • Induction and Regulation of the Innate Immune Response in Helicobacter pylori Infection, 2022, Cellular and Molecular Gastroenterology and Hepatology

Additional relevant papers involving related research topics include:

  • Spermine oxidase mediates Helicobacter pylori-induced gastric inflammation, DNA damage, and carcinogenic signaling, 2020, Oncogene
  • CCL11 exacerbates colitis and inflammation-associated colon tumorigenesis, 2021, Oncogene
  • Cystathionine γ-lyase exacerbates Helicobacter pylori immunopathogenesis by promoting macrophage metabolic remodeling and activation, 2022, JCI Insight

Best Publications

  • Induction of polyamine oxidase 1 by Helicobacter pylori causes macrophage apoptosis by hydrogen peroxide release and mitochondrial membrane depolarization.

    Rupesh Chaturvedi;Yulan Cheng;Mohammad Asim;Françoise I. Bussière

  • Anxiolytic properties of agomelatine, an antidepressant with melatoninergic and serotonergic properties: role of 5-HT2C receptor blockade

    Mark J. Millan;Mauricette Brocco;Alain Gobert;Anne Dekeyne

  • Helicobacter pylori induces macrophage apoptosis by activation of arginase II.

    Alain P. Gobert;Yulan Cheng;Jian Ying Wang;Jean Luc Boucher

  • l-Arginine Availability Modulates Local Nitric Oxide Production and Parasite Killing in Experimental Trypanosomiasis

    Alain P. Gobert;Alain P. Gobert;Sylvie Daulouede;Michel Lepoivre;Jean Luc Boucher

  • Spermine Oxidase Mediates the Gastric Cancer Risk Associated With Helicobacter pylori CagA

    Rupesh Chaturvedi;Mohammad Asim;Mohammad Asim;Judith Romero-Gallo;Daniel P. Barry;Daniel P. Barry

  • Arginases in parasitic diseases.

    Unknown

  • Cutting edge: urease release by Helicobacter pylori stimulates macrophage inducible nitric oxide synthase.

    Alain P. Gobert;Benjamin D. Mersey;Yulan Cheng;Darren R. Blumberg

  • Ornithine decarboxylase regulates M1 macrophage activation and mucosal inflammation via histone modifications

    Dana M. Hardbower;Mohammad Asim;Paula B. Luis;Kshipra Singh

  • Spermine causes loss of innate immune response to Helicobacter pylori by inhibition of inducible nitric-oxide synthase translation.

    Françoise I. Bussière;Rupesh Chaturvedi;Yulan Cheng;Alain P. Gobert

  • Selective blockade of dopamine D3 versus D2 receptors enhances frontocortical cholinergic transmission and social memory in rats: a parallel neurochemical and behavioural analysis

    Mark J. Millan;Benjamin Di Cara;Anne Dekeyne;Fany Panayi

  • Protective Role of Arginase in a Mouse Model of Colitis

    Alain P. Gobert;Yulan Cheng;Mahmood Akhtar;Benjamin D. Mersey

  • The role of polyamines in the regulation of macrophage polarization and function.

    Yvonne L Latour;Yvonne L Latour;Alain P Gobert;Alain P Gobert;Keith T Wilson

  • Polyamines Impair Immunity to Helicobacter pylori by Inhibiting L-Arginine Uptake Required for Nitric Oxide Production

    Rupesh Chaturvedi;Rupesh Chaturvedi;Mohammad Asim;Mohammad Asim;Svea Hoge;Svea Hoge;Nuruddeen D. Lewis

  • Mouse Strain Susceptibility to Trypanosome Infection: An Arginase-Dependent Effect

    Sébastien Duleu;Philippe Vincendeau;Pierrette Courtois;Silla Semballa

  • Helicobacter pylori induces ERK-dependent formation of a phospho-c-Fos c-Jun activator protein-1 complex that causes apoptosis in macrophages.

    Mohammad Asim;Mohammad Asim;Rupesh Chaturvedi;Rupesh Chaturvedi;Svea Hoge;Svea Hoge;Nuruddeen D. Lewis

  • Immune Evasion by Helicobacter pylori Is Mediated by Induction of Macrophage Arginase II

    Nuruddeen D. Lewis;Mohammad Asim;Mohammad Asim;Daniel P. Barry;Daniel P. Barry;Thibaut de Sablet;Thibaut de Sablet

  • Differential expression of stx2 variants in Shiga toxin-producing Escherichia coli belonging to seropathotypes A and C

    Thibaut de Sablet;Yolande Bertin;Marjolaine Vareille;Jean-Pierre Girardeau

  • Selective blockade of neurokinin (NK)1 receptors facilitates the activity of adrenergic pathways projecting to frontal cortex and dorsal hippocampus in rats

    Mark J. Millan;Françoise Lejeune;Guillaume De Nanteuil;Alain Gobert

  • Nitric oxide inhibits Shiga-toxin synthesis by enterohemorrhagic Escherichia coli

    Marjolaine Vareille;Thibaut de Sablet;Thomas Hindré;Christine Martin

  • Modulation of mesolimbic dopamine release by the selective dopamine D3 receptor antagonist, (+)-S 14297

    Jean-Michel Rivet;Valérie Audinot;Alain Gobert;Jean-Louis Peglion

Frequent Co-Authors

Mark J. Millan
Mark J. Millan University of Glasgow
Keith T. Wilson
Keith T. Wilson Vanderbilt University Medical Center
Rupesh Chaturvedi
Rupesh Chaturvedi Jawaharlal Nehru University
Richard M. Peek
Richard M. Peek Vanderbilt University Medical Center
Christine Martin
Christine Martin University of Clermont Auvergne
Robert A. Casero
Robert A. Casero Johns Hopkins University School of Medicine
Kevin L. Schey
Kevin L. Schey Vanderbilt University
Pelayo Correa
Pelayo Correa Vanderbilt University
John L. Cleveland
John L. Cleveland Moffitt Cancer Center

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