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Peter Nygren

Peter Nygren

D-Index & Metrics

Biology and Biochemistry

D-Index
59
Citations
10461
World Ranking
12743
National Ranking
190

Overview

Peter Nygren is affiliated with Uppsala University in Sweden. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with particular focus on Oncology, Cancer Research, and Molecular Biology subfields.

The scientist's work addresses several main topics, including:

  • Colorectal Cancer Treatments and Studies
  • Cancer Research and Treatments
  • Cancer, Hypoxia, and Metabolism
  • Cancer, Lipids, and Metabolism
  • Pancreatic and Hepatic Oncology Research
  • Cancer survivorship and care
  • Ferroptosis and cancer prognosis

Peter Nygren has contributed research articles to multiple scientific journals with frequent publications in:

  • Scientific Reports
  • Journal of Clinical Oncology
  • Blood
  • Scandinavian Journal of Medicine and Science in Sports
  • Psycho-Oncology

Recent noteworthy papers include:

  • Does exercise intensity matter for fatigue during (neo-)adjuvant cancer treatment? The Phys-Can randomized clinical trial, 2021, Scandinavian Journal of Medicine and Science in Sports
  • Cocreated internet-based stepped care for individuals with cancer and concurrent symptoms of anxiety and depression: Results from the U-CARE AdultCan randomized controlled trial, 2020, Psycho-Oncology
  • A phase 2a clinical study on the safety and efficacy of individualized dosed mebendazole in patients with advanced gastrointestinal cancer, 2021, Scientific Reports
  • Sorafenib and nitazoxanide disrupt mitochondrial function and inhibit regrowth capacity in three-dimensional models of hepatocellular and colorectal carcinoma, 2022, Scientific Reports
  • Exploiting loss of heterozygosity for allele-selective colorectal cancer chemotherapy, 2020, Nature Communications

Collaboration is a significant aspect of Peter Nygren's research activities. Frequent co-authors include Claes Andersson, Mårten Fryknäs, Kristin Blom, and Rolf Larsson, reflecting ongoing partnerships within their scientific network.

Best Publications

  • Aminopeptidase N (CD13) as a target for cancer chemotherapy

    Malin Wickström;Rolf Larsson;Peter Nygren;Joachim Gullbo

  • Laboratory determination of chemotherapeutic drug resistance in tumor cells from patients with leukemia, using a fluorometric microculture cytotoxicity assay (FMCA).

    Rolf Larsson;Jörgen Kristensen;Charlotta Sandberg;Peter Nygren

  • A systematic overview of chemotherapy effects in colorectal cancer.

    Peter Ragnhammar;Larsolof Hafström;Peter Nygren;Bengt Glimelius

  • The fluorometric microculture cytotoxicity assay

    Elin Lindhagen;Peter Nygren;Rolf Larsson

  • A systematic overview of chemotherapy effects in breast cancer.

    Jonas Bergh;Per-Ebbe Jönsson;Bengt Glimelius;Peter Nygren

  • Induction of mitochondrial dysfunction as a strategy for targeting tumour cells in metabolically compromised microenvironments

    Xiaonan Zhang;Mårten Fryknäs;Emma Hernlund;Walid Fayad

  • Safety and efficacy of NAD depleting cancer drugs: results of a phase I clinical trial of CHS 828 and overview of published data.

    Anne von Heideman;Åke Berglund;Rolf Larsson;Peter Nygren

  • Loss of cancer drug activity in colon cancer HCT-116 cells during spheroid formation in a new 3-D spheroid cell culture system.

    Henning Karlsson;Mårten Fryknäs;Rolf Larsson;Peter Nygren

  • Improved survival in patients with peritoneal metastases from colorectal cancer: a preliminary study.

    H Mahteme;J Hansson;Åke Berglund;Lars Påhlman

  • Inhibition of proteasome activity, nuclear factor-KB translocation and cell survival by the antialcoholism drug disulfiram

    Henrik Lövborg;Fredrik Öberg;Linda Rickardson;Joachim Gullbo

  • A systematic overview of chemotherapy effects in gastric cancer.

    Karl Gunnar Janunger;Larsolof Hafström;Peter Nygren;Bengt Glimelius

  • Repositioning of the anthelmintic drug mebendazole for the treatment for colon cancer

    Peter Nygren;Mårten Fryknäs;Bengt Ågerup;Rolf Larsson

  • Pharmacological profiling of disulfiram using human tumor cell lines and human tumor cells from patients

    Malin Wickström;Katarina Danielsson;Linda Rickardson;Joachim Gullbo

  • A systematic overview of chemotherapy effects in ovarian cancer.

    Thomas Högberg;Bengt Glimelius;Peter Nygren

  • What is cancer chemotherapy

    Peter Nygren

  • The initial change in tumor size predicts response and survival in patients with metastatic colorectal cancer treated with combination chemotherapy

    C Suzuki;L Blomqvist;Anders Sundin;H Jacobsson

  • Impact of fish oil and melatonin on cachexia in patients with advanced gastrointestinal cancer: A randomized pilot study

    Christina Persson;Bengt Glimelius;Johan Rönnelid;Peter Nygren

  • Three-Dimensional Cell Culture-Based Screening Identifies the Anthelmintic Drug Nitazoxanide as a Candidate for Treatment of Colorectal Cancer

    Wojciech Senkowski;Xiaonan Zhang;Maria Hägg Olofsson;Ruben Isacson

  • Cytoreductive surgery and intraperitoneal chemotherapy for colorectal peritoneal carcinomatosis: Prognosis and treatment of recurrences in a cohort study

    Peter H Cashin;Wilhelm Graf;Peter Nygren;Haile Mahteme

  • The Fluorometric Microculture Cytotoxicity Assay. Nat Protoc 3:1364

    Elin Lindhagen;Peter Nygren;Rolf Larsson

Frequent Co-Authors

Rolf Larsson
Rolf Larsson Uppsala University
Bengt Glimelius
Bengt Glimelius Uppsala University
Jonas Bergh
Jonas Bergh Karolinska Institute
Kenneth Nilsson
Kenneth Nilsson Uppsala University
Göran Åkerström
Göran Åkerström Uppsala University
Stig Linder
Stig Linder Linköping University
Christer Sundström
Christer Sundström Uppsala University
Lars Påhlman
Lars Påhlman Uppsala University
Anders Isaksson
Anders Isaksson Lund University
Anders Nilsson
Anders Nilsson Stockholm University

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