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Rolf Larsson

Rolf Larsson

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Biology and Biochemistry
Sweden
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
79
Citations
21275
World Ranking
4338
National Ranking
65

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Sweden Leader Award

Overview

Rolf Larsson is affiliated with Uppsala University in Sweden and has conducted research primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work extensively covers subfields including Molecular Biology, Oncology, Cancer Research, Pulmonary and Respiratory Medicine, and Public Health, Environmental and Occupational Health.

The scientist's research topics focus on Acute Lymphoblastic Leukemia, Cancer related to Hypoxia and Metabolism, Epigenetics and DNA Methylation, Cancer Lipids and Metabolism, Cancer Research and Treatments, Peptidase Inhibition and Analysis, and Cell Adhesion Molecules Research.

Among their recent papers are:

  • Increased levels of plasma cytokines and correlations to organ failure and 30-day mortality in critically ill Covid-19 patients, 2020, Cytokine
  • Sorafenib and nitazoxanide disrupt mitochondrial function and inhibit regrowth capacity in three-dimensional models of hepatocellular and colorectal carcinoma, 2022, Scientific Reports
  • Cell-lineage controlled epigenetic regulation in glioblastoma stem cells determines functionally distinct subgroups and predicts patient survival, 2022, Nature Communications
  • DNA Methylation Signatures Predict Cytogenetic Subtype and Outcome in Pediatric Acute Myeloid Leukemia (AML), 2021, Genes
  • Mebendazole is unique among tubulin-active drugs in activating the MEK-ERK pathway, 2020, Scientific Reports

Rolf Larsson has collaborated frequently with several researchers including Mårten Fryknäs, Claes Andersson, Kristin Blom, Peter Nygren, and Malin Jarvius.

Their work has been published in multiple venues, with notable frequency in Blood, Scientific Reports, Cytokine, Nature Communications, and Genes.

Best Publications

  • Statistisk verktygslåda - samhällsvetenskaplig orsaksanalys med kvantitativa metoder

    Göran Djurfeldt;Rolf Larsson;Ola Stjärnhagen

  • Likelihood-based cointegration tests in heterogeneous panels

    Rolf Larsson;Johan Lyhagen;Mickael Löthgren

  • Inhibition of proteasome deubiquitinating activity as a new cancer therapy

    Pádraig D'Arcy;Slavica Brnjic;Maria Hägg Olofsson;Mårten Fryknäs

  • Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemia

    Jessica Nordlund;Christofer L Bäcklin;Per Wahlberg;Stephan Busche

  • Isolated human islets trigger an instant blood mediated inflammatory reaction: implications for intraportal islet transplantation as a treatment for patients with type 1 diabetes.

    William Bennet;Carl-Gustav Groth;Rolf Larsson;Bo Nilsson

  • Aminopeptidase N (CD13) as a target for cancer chemotherapy

    Malin Wickström;Rolf Larsson;Peter Nygren;Joachim Gullbo

  • Inhibition of thrombin abrogates the instant blood-mediated inflammatory reaction triggered by isolated human islets : possible application of the thrombin inhibitor melagatran in clinical islet transplantation.

    Lisa Özmen;Kristina Nilsson Ekdahl;Graciela Elgue;Rolf Larsson

  • Cyclotides : a novel type of cytotoxic agents

    Petra Lindholm;Ulf Göransson;Senia Johansson;Per Claeson

  • Laboratory determination of chemotherapeutic drug resistance in tumor cells from patients with leukemia, using a fluorometric microculture cytotoxicity assay (FMCA).

    Rolf Larsson;Jörgen Kristensen;Charlotta Sandberg;Peter Nygren

  • The fluorometric microculture cytotoxicity assay

    Elin Lindhagen;Peter Nygren;Rolf Larsson

  • Islet Surface Heparinization Prevents the Instant Blood-Mediated Inflammatory Reaction in Islet Transplantation

    Sanja Cabric;Javier Sanchez;Torbjörn Lundgren;Aksel Foss

  • The African Food Crisis: Lessons from the Asian Green Revolution

    Göran Djurfeldt;Hans Holmén;Magnus Jirström;Rolf Larsson

  • Cytotoxic cyclotides from Viola tricolor.

    Erika Svangård;Ulf Göransson;Zozan Hocaoglu;Joachim Gullbo

  • Induction of mitochondrial dysfunction as a strategy for targeting tumour cells in metabolically compromised microenvironments

    Xiaonan Zhang;Mårten Fryknäs;Emma Hernlund;Walid Fayad

  • Damage to porcine islets of Langerhans after exposure to human blood in vitro, or after intraportal transplantation to cynomologus monkeys: protective effects of sCR1 and heparin.

    William Bennet;Berit Sundberg;Torbj rn Lundgren;Annika Tibell

  • Titanium is a highly thrombogenic biomaterial: possible implications for osteogenesis.

    Jaan Hong;Joakim Andersson;Kristina Nilsson Ekdahl;Graciela Elgue

  • Clonal Variation in Drug and Radiation Response among Glioma-Initiating Cells Is Linked to Proneural-Mesenchymal Transition

    Anna Segerman;Anna Segerman;Mia Niklasson;Caroline Haglund;Tobias Bergström

  • Safety and efficacy of NAD depleting cancer drugs: results of a phase I clinical trial of CHS 828 and overview of published data.

    Anne von Heideman;Åke Berglund;Rolf Larsson;Peter Nygren

  • Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.

    Gustav Ahlin;Johan Karlsson;Jenny M. Pedersen;Lena Gustavsson

  • The Fluorometric Microculture Cytotoxicity Assay. Nat Protoc 3:1364

    Elin Lindhagen;Peter Nygren;Rolf Larsson

Frequent Co-Authors

Peter Nygren
Peter Nygren Uppsala University
Stig Linder
Stig Linder Linköping University
Bo Nilsson
Bo Nilsson Uppsala University
Göran Åkerström
Göran Åkerström Uppsala University
Kenneth Nilsson
Kenneth Nilsson Uppsala University
Jonas Bergh
Jonas Bergh Karolinska Institute
Lars Bohlin
Lars Bohlin Uppsala University
Christer Sundström
Christer Sundström Uppsala University
Kristina Nilsson Ekdahl
Kristina Nilsson Ekdahl Uppsala University
Olle Korsgren
Olle Korsgren Uppsala University

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