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Medicine

D-Index
104
Citations
39451
World Ranking
7058
National Ranking
270

Research.com Recognitions

  • 2018 - Fellow of the Royal Society of Canada Academy of Science

Overview

Pierre Blier is affiliated with the University of Ottawa in Canada and has a research focus primarily within the fields of Medicine and Neuroscience. Their work spans areas such as Pharmacology, Ecology, Cognitive Neuroscience, Cellular and Molecular Neuroscience, and Psychiatry and Mental Health.

The main topics covered by their research include Treatment of Major Depression, Physiological and Biochemical Adaptations, Functional Brain Connectivity Studies, Tryptophan and Brain Disorders, Mental Health Research Topics, Neurotransmitter Receptor Influence on Behavior, and Aquaculture Nutrition and Growth.

Frequent publication venues for their research include The International Journal of Neuropsychopharmacology, Journal of Experimental Biology, The Canadian Journal of Psychiatry, Journal of Psychopharmacology, and Conservation Physiology.

Recent significant papers by Pierre Blier include:

  • The identification, assessment and management of difficult-to-treat depression: An international consensus statement (2020), Journal of Affective Disorders
  • A Delphi-method-based consensus guideline for definition of treatment-resistant depression for clinical trials (2021), Molecular Psychiatry
  • Canadian Network for Mood and Anxiety Treatments (CANMAT) 2023 Update on Clinical Guidelines for Management of Major Depressive Disorder in Adults: Réseau canadien pour les traitements de l'humeur et de l'anxiété (CANMAT) 2023: Mise à jour des lignes directrices cliniques pour la prise en charge du trouble dépressif majeur chez les adultes (2024), The Canadian Journal of Psychiatry
  • The Canadian Network for Mood and Anxiety Treatments (CANMAT) Task Force Recommendations for the Use of Racemic Ketamine in Adults with Major Depressive Disorder: Recommandations Du Groupe De Travail Du Réseau Canadien Pour Les Traitements De L'humeur Et De L'anxiété (Canmat) Concernant L'utilisation De La Kétamine Racémique Chez Les Adultes Souffrant De Trouble Dépressif Majeur (2020), The Canadian Journal of Psychiatry
  • International pooled patient-level meta-analysis of ketamine infusion for depression: In search of clinical moderators (2022), Molecular Psychiatry

Pierre Blier has collaborated frequently with several researchers, including Sidney H. Kennedy, Roumen Milev, Raymond W. Lam, Benício N. Frey, and Sagar V. Parikh. These co-authors have appeared alongside Blier in multiple scientific publications.

Outside of individual articles, Blier has been involved with academic contributions to journals renowned in Psychiatry and Neuropsychopharmacology as well as broader biological sciences.

They have been recognized as a Fellow of the Royal Society of Canada since 2018 by the Academy of Science.

Best Publications

  • Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 Clinical Guidelines for the Management of Adults with Major Depressive Disorder Section 3. Pharmacological Treatments

    Sidney H. Kennedy;Raymond W. Lam;Roger S. McIntyre;S. Valérie Tourjman

  • Differences between males and females in rates of serotonin synthesis in human brain.

    S. Nishizawa;C. Benkelfat;S. N. Young;M. Leyton

  • Monoamine neurocircuitry in depression and strategies for new treatments.

    Michel Hamon;Pierre Blier

  • Efficacy of Esketamine Nasal Spray Plus Oral Antidepressant Treatment for Relapse Prevention in Patients With Treatment-Resistant Depression: A Randomized Clinical Trial.

    Ella J. Daly;Madhukar H. Trivedi;Adam Janik;Honglan Li

  • Efficacy and Safety of Fixed-Dose Esketamine Nasal Spray Combined With a New Oral Antidepressant in Treatment-Resistant Depression: Results of a Randomized, Double-Blind, Active-Controlled Study (TRANSFORM-1).

    Maggie Fedgchin;Madhukar Trivedi;Ella J Daly;Rama Melkote

  • Genetic and pharmacological disruption of neurokinin 1 receptor function decreases anxiety-related behaviors and increases serotonergic function.

    Luca Santarelli;Gabriella Gobbi;Pierre C. Debs;Etienne L. Sibille

  • Presynaptic and postsynaptic modifications of the serotonin system by long-term administration of antidepressant treatments. An in vivo electrophysiologic study in the rat.

    Y Chaput;C de Montigny;P Blier

  • Functional interactions between dopamine, serotonin and norepinephrine neurons: an in-vivo electrophysiological study in rats with monoaminergic lesions

    Bruno P. Guiard;Mostafa El Mansari;Zul Merali;Pierre Blier

  • Brain Regional α-[11C]Methyl-l-Tryptophan Trapping in Impulsive Subjects With Borderline Personality Disorder

    Marco Leyton;Hidehiko Okazawa;Mirko Diksic;Joel Paris

  • Role of Somatodendritic 5-HT Autoreceptors in Modulating 5-HT Neurotransmissiona

    P. Blier;G. Piñeyro;M. El Mansari;R. Bergeron

  • The pharmacology of putative early-onset antidepressant strategies

    Pierre Blier

  • The International College of Neuro-Psychopharmacology (CINP) Treatment Guidelines for Bipolar Disorder in Adults (CINP-BD-2017), Part 3: The Clinical Guidelines.

    Konstantinos N Fountoulakis;Heinz Grunze;Eduard Vieta;Allan Young

  • Putative mechanisms of action of antidepressant drugs in affective and anxiety disorders and pain.

    Pierre Blier;Frances V. Abbott

  • Possible serotonergic mechanisms underlying the antidepressant and anti-obsessive–compulsive disorder responses

    Pierre Blier;Claude de Montigny

  • Selective activation of postsynaptic 5-HT1A receptors induces rapid antidepressant response.

    Pierre Blier;Richard Bergeron;Claude de Montigny

  • Which antidepressants have demonstrated superior efficacy? A review of the evidence.

    Stuart A. Montgomery;David S. Baldwin;Pierre Blier;Naomi A. Fineberg

  • Modulation of the firing activity of noradrenergic neurones in the rat locus coeruleus by the 5-hydroxtryptamine system

    Nasser Haddjeri;Claude De Montigny;Pierre Blier

  • Pharmacology of Rapid-Onset Antidepressant Treatment Strategies

    Pierre Blier

  • Desensitization of the neuronal 5-HT carrier following its long-term blockade

    G Pineyro;P Blier;T Dennis;C de Montigny

  • A double-blind, placebo-controlled trial of olanzapine addition in fluoxetine-refractory obsessive-compulsive disorder.

    Nathan A Shapira;Herbert E Ward;Miguel Mandoki;Tanya K Murphy

Frequent Co-Authors

C de Montigny
C de Montigny McGill University
Nasser Haddjeri
Nasser Haddjeri Claude Bernard University Lyon 1
Sidney H. Kennedy
Sidney H. Kennedy University Health Network
Verner Knott
Verner Knott University of Ottawa
Gustavo Turecki
Gustavo Turecki Douglas Mental Health University Institute
Roumen Milev
Roumen Milev Queen's University
Raymond W. Lam
Raymond W. Lam University of British Columbia
Siegfried Kasper
Siegfried Kasper Medical University of Vienna
Bruno P. Guiard
Bruno P. Guiard University of Toulouse-Jean Jaurès
Faranak Farzan
Faranak Farzan Simon Fraser University

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