Umberto Spampinato spends much of his time researching Internal medicine, Endocrinology, Dopamine, Striatum and Receptor. Many of his research projects under Endocrinology are closely connected to Glutamate aspartate transporter with Glutamate aspartate transporter, tying the diverse disciplines of science together. His work in the fields of Dopamine, such as Nucleus accumbens and Dopaminergic, intersects with other areas such as Degeneration.
His Nucleus accumbens research includes themes of SB-242084 and Ventral tegmental area. His Receptor research integrates issues from Steroid and Pharmacology. His Agonist study combines topics in areas such as Microdialysis and Antagonist.
His primary areas of investigation include Dopamine, Internal medicine, Endocrinology, Nucleus accumbens and Pharmacology. Umberto Spampinato is studying Striatum, which is a component of Dopamine. His Internal medicine course of study focuses on Anesthesia and Levodopa, Parkinsonism and Parkinson's disease.
His study on Endocrinology is mostly dedicated to connecting different topics, such as Agonist. The Nucleus accumbens study combines topics in areas such as SB-242084, Ventral tegmental area, Amphetamine and 5-HT2C receptor. His Pharmacology research incorporates elements of Paracrine signalling, Autocrine signalling, Haloperidol, Quinpirole and Dopamine agonist.
His scientific interests lie mostly in Dopamine, Pharmacology, Neuroscience, Nucleus accumbens and Receptor. His Dopamine research is multidisciplinary, relying on both RS-127445, 5-HT receptor, Neuron, Neurochemical and Dorsal raphe nucleus. His Pharmacology research is multidisciplinary, incorporating perspectives in Antiparkinson Agents, Cannabinoid, Autocrine signalling and Paracrine signalling.
His Nucleus accumbens study incorporates themes from Agonist and Striatum. His research investigates the connection between Agonist and topics such as SB-242084 that intersect with problems in Endocrinology. Umberto Spampinato focuses mostly in the field of Receptor, narrowing it down to matters related to Addiction and, in some cases, Central nervous system.
His primary scientific interests are in Dopamine, Neurochemical, Pharmacology, 5-HT2C receptor and Receptor. Umberto Spampinato studies Dopamine, focusing on Nucleus accumbens in particular. Nucleus accumbens is closely attributed to Glutamatergic in his research.
Umberto Spampinato has researched Neurochemical in several fields, including Agonist, Dopaminergic, Substance abuse, Addiction and Drug. His studies deal with areas such as SB-242084, Quinpirole, Autocrine signalling and Paracrine signalling as well as Pharmacology. His studies in Receptor integrate themes in fields like Hormone, Steroid and Pregnenolone.
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Constitutive Activity of the Serotonin2C Receptor Inhibits In Vivo Dopamine Release in the Rat Striatum and Nucleus Accumbens
Philippe De Deurwaerdère;Sylvia Navailles;Kelly A. Berg;William P. Clarke.
The Journal of Neuroscience (2004)
Novel pharmacological targets for the treatment of Parkinson's disease
Anthony H V Schapira;Erwan Bezard;Jonathan Brotchie;Frédéric Calon.
Nature Reviews Drug Discovery (2006)
Selective blockade of serotonin-2C/2B receptors enhances mesolimbic and mesostriatal dopaminergic function: a combined in vivo electrophysiological and microdialysis study.
G Di Giovanni;P De Deurwaerdére;M Di Mascio;V Di Matteo.
5-HT2A and 5-HT2C/2B receptor subtypes modulate dopamine release induced in vivo by amphetamine and morphine in both the rat nucleus accumbens and striatum.
Grégory Porras;Vincenzo Di Matteo;Claudia Fracasso;Guillaume Lucas.
Role of striatal serotonin2A and serotonin2C receptor subtypes in the control of in vivo dopamine outflow in the rat striatum.
Guillaume Lucas;Umberto Spampinato.
Journal of Neurochemistry (2001)
Pregnenolone Can Protect the Brain from Cannabis Intoxication
Monique Vallée;Monique Vallée;Sergio Vitiello;Sergio Vitiello;Luigi Bellocchio;Luigi Bellocchio;Etienne Hébert-Chatelain;Etienne Hébert-Chatelain.
In vivo release of [3H]γ-aminobutyric acid in the rat neostriatum—II. Opposing effects of D1 and D2 dopamine receptor stimulation in the dorsal caudate putamen
J.A. Girault;U. Spampinato;J. Glowinski;M.J. Besson.
Are there selective ligands for 5-HT1A and 5-HT1B receptor binding sites in brain?
M. Hamon;J-M. Cossery;U. Spampinato;H. Gozlan.
Trends in Pharmacological Sciences (1986)
Aging associated changes in serotoninergic and dopaminergic pre- and postsynaptic neurochemical markers in the rat brain.
H. Gozlan;G. Daval;D. Verge;U. Spampinato.
Neurobiology of Aging (1990)
Transient expression of 5-HT1A receptor binding sites in some areas of the rat CNS during postnatal development
G. Daval;D. Vergé;A. Becerril;H. Gozlan.
International Journal of Developmental Neuroscience (1987)
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