2026 Umberto Spampinato: Neuroscience Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Neuroscience	52	5404	4964	229	207	109	7716

Overview

Umberto Spampinato is affiliated with the University of Bordeaux in France. Their research primarily spans the fields of Medicine, Neuroscience, and Biochemistry, Genetics and Molecular Biology, with a focus on several subfields including Cellular and Molecular Neuroscience, Neurology, Molecular Biology, Pharmacology, and Epidemiology.

The main topics addressed in Spampinato's body of work include:

Neurotransmitter Receptor Influence on Behavior
Neurological disorders and treatments
Parkinson's Disease Mechanisms and Treatments
Receptor Mechanisms and Signaling
Neuroscience and Neuropharmacology Research
Genetic Neurodegenerative Diseases
Mitochondrial Function and Pathology

Spampinato's recent publications demonstrate a focus on receptor signaling and neuropsychiatric conditions, highlighting contributions such as:

"Signaling-specific inhibition of the CB1 receptor for cannabis use disorder: phase 1 and phase 2a randomized trials" (2023), published in Nature Medicine
"The Prevalence and Determinants of Neuropsychiatric Symptoms in Late-Stage Parkinsonism" (2020), published in Movement Disorders Clinical Practice
"Brain 5-HT1A Receptor Binding in Multiple System Atrophy: An [18F]-MPPF PET Study" (2020), published in Movement Disorders
"Serotonin2B receptor blockade in the rat dorsal raphe nucleus suppresses cocaine-induced hyperlocomotion through an opposite control of mesocortical and mesoaccumbens dopamine pathways" (2020), published in Neuropharmacology
"Differential expression of serotonin2B receptors in GABAergic and serotoninergic neurons of the rat and mouse dorsal raphe nucleus" (2022), published in Molecular and Cellular Neuroscience

Frequent collaborators in Spampinato's work include:

Adeline Cathala
Wassilios G. Meissner
Olivier Rascol
Jean-Michel Revest
Ana Marquès

The distinct publication venues where Spampinato often contributes are:

Movement Disorders
Nature Medicine
Movement Disorders Clinical Practice
Neuropharmacology
Molecular and Cellular Neuroscience

Best Publications

Novel pharmacological targets for the treatment of Parkinson's disease

Anthony H V Schapira;Erwan Bezard;Jonathan Brotchie;Frédéric Calon

389
Citations
Constitutive Activity of the Serotonin2C Receptor Inhibits In Vivo Dopamine Release in the Rat Striatum and Nucleus Accumbens

Philippe De Deurwaerdère;Sylvia Navailles;Kelly A. Berg;William P. Clarke

386
Citations
Pregnenolone Can Protect the Brain from Cannabis Intoxication

Monique Vallée;Monique Vallée;Sergio Vitiello;Sergio Vitiello;Luigi Bellocchio;Luigi Bellocchio;Etienne Hébert-Chatelain;Etienne Hébert-Chatelain

352
Citations
Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study

Davina J Hensman Moss;Antonio F Pardiñas;Douglas Langbehn;Kitty Lo

347
Citations
5-HT2A and 5-HT2C/2B receptor subtypes modulate dopamine release induced in vivo by amphetamine and morphine in both the rat nucleus accumbens and striatum.

Grégory Porras;Vincenzo Di Matteo;Claudia Fracasso;Guillaume Lucas

272
Citations
Selective blockade of serotonin-2C/2B receptors enhances mesolimbic and mesostriatal dopaminergic function: a combined in vivo electrophysiological and microdialysis study.

G Di Giovanni;P De Deurwaerdére;M Di Mascio;V Di Matteo

270
Citations
Role of striatal serotonin2A and serotonin2C receptor subtypes in the control of in vivo dopamine outflow in the rat striatum.

Guillaume Lucas;Umberto Spampinato

240
Citations
In vivo release of [3H]γ-aminobutyric acid in the rat neostriatum—II. Opposing effects of D1 and D2 dopamine receptor stimulation in the dorsal caudate putamen

J.A. Girault;U. Spampinato;J. Glowinski;M.J. Besson

218
Citations
Are there selective ligands for 5-HT1A and 5-HT1B receptor binding sites in brain?

M. Hamon;J-M. Cossery;U. Spampinato;H. Gozlan

200
Citations
Aging associated changes in serotoninergic and dopaminergic pre- and postsynaptic neurochemical markers in the rat brain.

H. Gozlan;G. Daval;D. Verge;U. Spampinato

200
Citations
Transient expression of 5-HT1A receptor binding sites in some areas of the rat CNS during postnatal development

G. Daval;D. Vergé;A. Becerril;H. Gozlan

194
Citations
Role of Serotonin2A and Serotonin2B/2C Receptor Subtypes in the Control of Accumbal and Striatal Dopamine Release Elicited In Vivo by Dorsal Raphe Nucleus Electrical Stimulation

Philippe De Deurwaerdère;Umberto Spampinato

191
Citations
Opposite Change of In Vivo Dopamine Release in the Rat Nucleus Accumbens and Striatum That Follows Electrical Stimulation of Dorsal Raphe Nucleus: Role of 5-HT3 Receptors

Philippe De Deurwaerdère;Luis Stinus;Umberto Spampinato

177
Citations
In Vivo Release of Endogenous Amino Acids from the Rat Striatum: Further Evidence for a Role of Glutamate and Aspartate in Corticostriatal Neurotransmission

Jean Antoine Girault;Luis Barbeito;Umberto Spampinato;Henri Gozlan

171
Citations
Evidence for 5-HT4 receptor subtype involvement in the enhancement of striatal dopamine release induced by serotonin: a microdialysis study in the halothane-anesthetized rat.

N. Bonhomme;P. De Deurwaèrdere;M. Le Moal;U. Spampinato

163
Citations
Physiological relevance of constitutive activity of 5-HT2A and 5-HT2C receptors

Kelly A. Berg;John A. Harvey;Umberto Spampinato;William P. Clarke

156
Citations
Differential regulation of the mesoaccumbens dopamine circuit by serotonin2C receptors in the ventral tegmental area and the nucleus accumbens: an in vivo microdialysis study with cocaine.

Sylvia Navailles;Delphine Moison;Kathryn A Cunningham;Umberto Spampinato

152
Citations
Current status of inverse agonism at serotonin2A (5-HT2A) and 5-HT2C receptors.

V.J. Aloyo;K.A. Berg;U. Spampinato;W.P. Clarke

138
Citations
8-OH-DPAT, a 5-HT1A agonist and ritanserin, a 5-HT2A/C antagonist, reverse haloperidol-induced catalepsy in rats independently of striatal dopamine release

Guillaume Lucas;Norbert Bonhomme;Philippe De Deurwaerdère;Michel Le Moal

129
Citations
In vivo evidence that 5-HT2C receptor antagonist but not agonist modulates cocaine-induced dopamine outflow in the rat nucleus accumbens and striatum.

Sylvia Navailles;Philippe De Deurwaerdère;Grégory Porras;Umberto Spampinato

116
Citations
Fine-tuning serotonin2c receptor function in the brain: molecular and functional implications.

Kelly A. Berg;William P. Clarke;Kathryn A. Cunningham;Umberto Spampinato

114
Citations