Wouter Koek

Best Publications

• MK-801, a proposed noncompetitive antagonist of excitatory amino acid neurotransmission, produces phencyclidine-like behavioral effects in pigeons, rats and rhesus monkeys.

  W Koek;J H Woods;G D Winger

  450
  Citations

• Selective blockade of N-methyl-D-aspartate (NMDA)-induced convulsions by NMDA antagonists and putative glycine antagonists: relationship with phencyclidine-like behavioral effects.

  Wouter Koek;F. C. Colpaert

  297
  Citations

• WIN55,212‐2, a cannabinoid receptor agonist, protects against nigrostriatal cell loss in the 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine mouse model of Parkinson’s disease

  David A. Price;Alex A. Martinez;Alexandre Seillier;Wouter Koek

  240
  Citations

• Organic cation transporter 3: Keeping the brake on extracellular serotonin in serotonin-transporter-deficient mice.

  Nicole L. Baganz;Rebecca E. Horton;Alfredo S. Calderon;W. Anthony Owens

  189
  Citations

• Opiate self-administration as a measure of chronic nociceptive pain in arthritic rats

  F. C. Colpaert;J. P. Tarayre;M. Alliaga;L. A. Bruins Slot

  184
  Citations

• Differential effects of direct and indirect dopamine agonists on eye blink rate in cynomolgus monkeys

  Mark S. Kleven;Wouter Koek

  181
  Citations

• A randomized control trial to establish the feasibility and safety of rapamycin treatment in an older human cohort: Immunological, physical performance, and cognitive effects.

  Ellen Kraig;Leslie A. Linehan;Hanyu Liang;Terry Q. Romo

  161
  Citations

• Large-amplitude 5-HT1A receptor activation: a new mechanism of profound, central analgesia

  F.C Colpaert;J.P Tarayre;W Koek;P.J Pauwels

  154
  Citations

• Behavioral analyses of GHB: Receptor mechanisms

  Unknown

  147
  Citations

• Novel derivatives of 2-pyridinemethylamine as selective, potent, and orally active agonists at 5-HT1A receptors.

  Bernard Vacher;Bernard Bonnaud;Philippe Funes;Nathalie Jubault

  143
  Citations

• The phencyclidine (PCP) analog N-[1-(2-benzo(B)thiophenyl) cyclohexyl]piperidine shares cocaine-like but not other characteristic behavioral effects with PCP, ketamine and MK-801.

  Wouter Koek;F. C. Colpaert;J. H. Woods;J. M. Kamenka

  141
  Citations

• F15599, a highly selective post-synaptic 5-HT1A receptor agonist: In-vivo profile in behavioural models of antidepressant and serotonergic activity

  Marie Bernadette Assié;Laurent Bardin;Agnès L. Auclair;Elisabeth Carilla-Durand

  135
  Citations

• Effects of 5-HT1A receptor antagonists on hippocampal 5-hydroxytryptamine levels: (S)-WAY100135, but not WAY100635, has partial agonist properties

  Marie Bernadette Assié;Wouter Koek

  125
  Citations

• NMDA antagonists make learning and recall state-dependent.

  A. Jackson;Wouter Koek;F. C. Colpaert

  115
  Citations

• 5-HT1A receptor activation and anti-cataleptic effects: high-efficacy agonists maximally inhibit haloperidol-induced catalepsy.

  Eric P.M Prinssen;Francis C Colpaert;Wouter Koek

  114
  Citations

• Decynium-22 Enhances SSRI-Induced Antidepressant-Like Effects in Mice: Uncovering Novel Targets to Treat Depression

  Rebecca E. Horton;Deana M. Apple;W. Anthony Owens;Nicole L. Baganz

  111
  Citations

• A simple and rapid method for assessing similarities among directly observable behavioral effects of drugs: PCP-like effects of 2-amino-5-phosphonovalerate in rats.

  Wouter Koek;J. H. Woods;P. Ornstein

  104
  Citations

• Catecholamine/Serotonin Interactions: Systems Thinking for Brain Function and Disease

  Julie G. Hensler;Francesc Artigas;Analía Bortolozzi;Analía Bortolozzi;Lynette C. Daws

  104
  Citations

• In the formalin model of tonic nociceptive pain, 8-OH-DPAT produces 5-HT1A receptor-mediated, behaviorally specific analgesia.

  Laurent Bardin;Jean Pierre Tarayre;Wouter Koek;Francis C. Colpaert

  100
  Citations

• Discriminative Stimulus Properties of Cocaine: Enhancement by Monoamine Reuptake Blockers

  Mark S. Kleven;Wouter Koek

  99
  Citations