Wojciech Danysz

Best Publications

• Memantine is a clinically well tolerated N-methyl-d-aspartate (NMDA) receptor antagonist—a review of preclinical data

  C.G. Parsons;W. Danysz;G. Quack

  1238
  Citations

• Glycine and N-Methyl-d-Aspartate Receptors: Physiological Significance and Possible Therapeutic Applications

  Wojciech Danysz;Chris G. Parsons

  877
  Citations

• Memantine: a NMDA receptor antagonist that improves memory by restoration of homeostasis in the glutamatergic system--too little activation is bad, too much is even worse.

  Chris G. Parsons;Albrecht Stöffler;Wojciech Danysz

  847
  Citations

• Alzheimer's disease, β-amyloid, glutamate, NMDA receptors and memantine – searching for the connections

  Wojciech Danysz;Chris G Parsons

  639
  Citations

• Glutamate in CNS disorders as a target for drug development: an update.

  C G Parsons;W Danysz;G Quack

  582
  Citations

• The NMDA Receptor Antagonist Memantine as a Symptomatological and Neuroprotective Treatment for Alzheimer's Disease: Preclinical Evidence

  Wojciech Danysz;Chris G. Parsons

  527
  Citations

• Aminoadamantanes as NMDA receptor antagonists and antiparkinsonian agents : Preclinical studies

  W. Danysz;C.G. Parsons;J. Kornhuber;W.J. Schmidt

  442
  Citations

• Comparison of the potency, kinetics and voltage-dependency of a series of uncompetitive NMDA receptor antagonists in vitro with anticonvulsive and motor impairment activity in vivo

  C.G. Parsons;G. Quack;I. Bresink;L. Baran

  380
  Citations

• Memantine and cholinesterase inhibitors: complementary mechanisms in the treatment of Alzheimer's disease.

  Chris G. Parsons;Wojciech Danysz;Andrzej Dekundy;Irena Pulte

  371
  Citations

• Antagonism of metabotropic glutamate receptor type 5 attenuates l-DOPA-induced dyskinesia and its molecular and neurochemical correlates in a rat model of Parkinson's disease.

  Flora Mela;Matteo Marti;Andrzej Dekundy;Wojciech Danysz

  291
  Citations

• Learning impairment in rats by N-methyl-D-aspartate receptor antagonists

  W. Danysz;J.T. Wroblewski;E. Costa

  276
  Citations

• Modulation of l-DOPA-induced abnormal involuntary movements by clinically tested compounds: Further validation of the rat dyskinesia model

  Andrzej Dekundy;Martin Lundblad;Wojciech Danysz;M. Angela Cenci

  273
  Citations

• Modulation of glutamate receptors: molecular mechanisms and functional implications.

  J T Wroblewski;W Danysz

  251
  Citations

• Modulation of learning processes by ionotropic glutamate receptor ligands.

  Danysz W;Zajaczkowski W;Parsons Cg

  246
  Citations

• Novel systemically active antagonists of the glycine site of the N-methyl-D-aspartate receptor: electrophysiological, biochemical and behavioral characterization.

  Parsons Cg;Danysz W;Quack G;Hartmann S

  235
  Citations

• Synergistic effect of uncompetitive NMDA receptor antagonists and antidepressant drugs in the forced swimming test in rats.

  Zofia Rogóż;Grażyna Skuza;Jerzy Maj;Wojciech Danysz

  235
  Citations

• Antidepressant-like effects of mGluR1 and mGluR5 antagonists in the rat forced swim and the mouse tail suspension tests.

  I.V. Belozertseva;T. Kos;P. Popik;W. Danysz

  230
  Citations

• Pharmacodynamics of Memantine: An Update

  G. Rammes;W. Danysz;C. G. Parsons

  225
  Citations

• Pharmacological Modulation of Glutamate Transmission in a Rat Model of l-DOPA-Induced Dyskinesia: Effects on Motor Behavior and Striatal Nuclear Signaling

  Daniella Rylander;Alessandra Recchia;Flora Mela;Andrzej Dekundy

  216
  Citations

• Glycine and D-serine increase the affinity of N-methyl-D-aspartate sensitive glutamate binding sites in rat brain synaptic membranes.

  E. Fadda;W. Danysz;J.T. Wroblewski;E. Costa

  197
  Citations