World's Best Scientists 2026 revealed!

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Medicine

D-Index
107
Citations
41374
World Ranking
6268
National Ranking
3343

Research.com Recognitions

  • 2019 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Robert Schwarcz is affiliated with the University of Maryland, Baltimore in the United States. Their research primarily spans the fields of Neuroscience and Medicine, with a focus on several intersecting subfields such as Biological Psychiatry, Social Psychology, Behavioral Neuroscience, Gastroenterology, and Epidemiology.

The main topics addressed in their work include:

  • Tryptophan and brain disorders
  • Neuroendocrine regulation and behavior
  • Stress Responses and Cortisol
  • Celiac Disease Research and Management
  • Microscopic Colitis
  • Bipolar Disorder and Treatment
  • Treatment of Major Depression

Robert Schwarcz has contributed to various academic venues, frequently publishing in:

  • SSRN Electronic Journal
  • Pharmacological Reviews
  • Psychopharmacology
  • Journal of Neuroscience Methods
  • European Journal of Neuroscience

The scientist's recent publications cover diverse topics in brain research and clinical studies, including:

  • Activation of alpha7 nicotinic and NMDA receptors is necessary for performance in a working memory task (2020, Psychopharmacology)
  • Neuroactive Kynurenines as Pharmacological Targets: New Experimental Tools and Exciting Therapeutic Opportunities (2024, Pharmacological Reviews)
  • White matter and latency of visual evoked potentials during maturation: A miniature pig model of adolescent development (2024, Journal of Neuroscience Methods)
  • Randomized Double Blind Inpatient Study of a Gluten-Free Diet in People with Schizophrenia (2025, SSRN Electronic Journal)
  • Functional Impairments in Learning and Signal Propagation Following Prenatal Kynurenine Treatment in Mice (2025, European Journal of Neuroscience)

Their research collaborations have included frequent co-authorship with several individuals:

  • Korrapati V. Sathyasaikumar (4 joint publications)
  • Peter Kochunov (3 joint publications)
  • Sarah M. Clark (3 joint publications)
  • Ana Pocivavsek (2 joint publications)
  • Sophie Erhardt (2 joint publications)

Robert Schwarcz was awarded the title Fellow of the American Association for the Advancement of Science (AAAS) in 2019.

Best Publications

  • Quinolinic acid: an endogenous metabolite that produces axon-sparing lesions in rat brain

    Robert Schwarcz;William O. Whetsell;Richard M. Mangano

  • Kynurenines in the mammalian brain: when physiology meets pathology

    Robert Schwarcz;John P. Bruno;Paul J. Muchowski;Hui-Qiu Wu

  • Lesion of striatal neurones with kainic acid provides a model for Huntington's chorea.

    Joseph T. Coyle;Robert Schwarcz

  • The Brain Metabolite Kynurenic Acid Inhibits α7 Nicotinic Receptor Activity and Increases Non-α7 Nicotinic Receptor Expression: Physiopathological Implications

    Corey Hilmas;Edna F. R. Pereira;Manickavasagom Alkondon;Arash Rassoulpour

  • Blood–Brain Barrier Transport of Kynurenines: Implications for Brain Synthesis and Metabolism

    Shinsuke Fukui;Robert Schwarcz;Stanley I. Rapoport;Yoshiaki Takada

  • Manipulation of Brain Kynurenines: Glial Targets, Neuronal Effects, and Clinical Opportunities

    Robert Schwarcz;Roberto Pellicciari

  • II: Excitotoxic models for neurodegenerative disorders

    Robert Schwarcz;Alan C. Foster;Edward D. French;William O. Whetsell

  • Increased cortical kynurenate content in schizophrenia.

    Robert Schwarcz;Arash Rassoulpour;Hui Qiu Wu;Deborah Medoff

  • Striatal lesions with kainic acid: neurochemical characteristics.

    Robert Schwarcz;Joseph T. Coyle

  • Ibotenic acid-induced neuronal degeneration: a morphological and neurochemical study.

    R. Schwarcz;T. Hökfelt;K. Fuxe;G. Jonsson

  • Kynurenine 3-monooxygenase inhibition in blood ameliorates neurodegeneration.

    Daniel Zwilling;Shao-Yi Huang;Korrapati V. Sathyasaikumar;Francesca M. Notarangelo

  • Dopamine receptors localised on cerebral cortical afferents to rat corpus striatum

    Robert Schwarcz;Ian Creese;Joseph T. Coyle;Solomon H. Snyder

  • Impaired Spatial Representation in CA1 after Lesion of Direct Input from Entorhinal Cortex

    Vegard Heimly Brun;Stefan Leutgeb;Hui-Qiu Wu;Robert Schwarcz

  • Kynurenic acid blocks neurotoxicity and seizures induced in rats by the related brain metabolite quinolinic acid.

    Alan C. Foster;Annamakia Vezzani;Edward D. French;Robert Schwarcz

  • Preferential neuronal loss in layer III of the entorhinal cortex in patients with temporal lobe epilepsy.

    Fu Du;William O. Whetsell;Bassei Abou-Khalil;Bennett Blumenkopf

  • Preferential neuronal loss in layer III of the medial entorhinal cortex in rat models of temporal lobe epilepsy

    Fu Du;T. Eid;E. W. Lothman;C. Kohler

  • The kynurenine pathway and the brain: Challenges, controversies and promises.

    Robert Schwarcz;Trevor W. Stone

  • Neostriatal and cortical quinolinate levels are increased in early grade Huntington's disease.

    Paolo Guidetti;Ruth E Luthi-Carter;Sarah J Augood;Robert Schwarcz

  • The kynurenine pathway of tryptophan degradation as a drug target.

    Robert Schwarcz

  • Comparison of ibotenate and kainate neurotoxicity in rat brain: a histological study.

    C Köhler;R Schwarcz

Frequent Co-Authors

Kjell Fuxe
Kjell Fuxe Karolinska Institute
Paul J. Muchowski
Paul J. Muchowski University of California, San Francisco
Joseph T. Coyle
Joseph T. Coyle Harvard University
Barry K. Carpenter
Barry K. Carpenter Cardiff University
Roberto Pellicciari
Roberto Pellicciari University of Perugia
William O. Whetsell
William O. Whetsell Vanderbilt University Medical Center
John P. Bruno
John P. Bruno The Ohio State University
Rosalinda C. Roberts
Rosalinda C. Roberts University of Alabama at Birmingham
Edson X. Albuquerque
Edson X. Albuquerque University of Maryland, Baltimore

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