What is he best known for?
The fields of study he is best known for:
- Neuroscience
- Dopamine
- Neurotransmitter
John P. Bruno spends much of his time researching Neuroscience, Cholinergic, Acetylcholine, Basal forebrain and Cholinergic neuron.
As a part of the same scientific study, John P. Bruno usually deals with the Neuroscience, concentrating on Kynurenic acid and frequently concerns with Kynurenine.
John P. Bruno interconnects Nucleus accumbens, Frontal lobe, Sensory system, Cortex and Neurochemical in the investigation of issues within Cholinergic.
His Acetylcholine research is multidisciplinary, relying on both Biomedical engineering, Microdialysis, Neurotransmitter and Analytical chemistry.
His study explores the link between Basal forebrain and topics such as Cerebral cortex that cross with problems in Thalamus and Brainstem.
His research investigates the connection between Cholinergic neuron and topics such as GABAergic that intersect with issues in Dopamine receptor D2 and Cholinesterase.
His most cited work include:
- The cognitive neuroscience of sustained attention: where top-down meets bottom-up. (802 citations)
- Kynurenines in the mammalian brain: when physiology meets pathology (757 citations)
- Cognitive functions of cortical acetylcholine: toward a unifying hypothesis (580 citations)
What are the main themes of his work throughout his whole career to date?
Neuroscience, Endocrinology, Internal medicine, Acetylcholine and Cholinergic are his primary areas of study.
In Neuroscience, John P. Bruno works on issues like Schizophrenia, which are connected to Psychosis.
In his study, which falls under the umbrella issue of Internal medicine, Morris water navigation task and Glutamatergic is strongly linked to Kynurenine.
John P. Bruno has included themes like Neurotransmitter, Amphetamine, Inverse agonist, Stimulation and Microdialysis in his Acetylcholine study.
Cholinergic is closely attributed to Sensory system in his study.
His Basal forebrain study combines topics in areas such as Cerebral cortex, Cholinergic neuron, GABAergic, Cortex and DNQX.
He most often published in these fields:
- Neuroscience (60.90%)
- Endocrinology (36.84%)
- Internal medicine (36.84%)
What were the highlights of his more recent work (between 2012-2020)?
- Neuroscience (60.90%)
- Glutamate receptor (10.53%)
- Kynurenic acid (12.03%)
In recent papers he was focusing on the following fields of study:
The scientist’s investigation covers issues in Neuroscience, Glutamate receptor, Kynurenic acid, Prefrontal cortex and Nicotinic agonist.
His research investigates the connection with Neuroscience and areas like Glutamatergic which intersect with concerns in Atrophy.
His Glutamate receptor research includes themes of NMDA receptor and Endocrinology, Stimulation, Dopamine.
His Kynurenic acid study combines topics from a wide range of disciplines, such as Allosteric modulator, Schizophrenia and Kynurenine.
His research in Kynurenine focuses on subjects like Morris water navigation task, which are connected to Dopaminergic, Kynurenine—oxoglutarate transaminase and Cholinergic.
John P. Bruno has included themes like GABAergic, Inhibitory postsynaptic potential, Neurotransmission, Disinhibition and Local field potential in his Prefrontal cortex study.
Between 2012 and 2020, his most popular works were:
- Early developmental elevations of brain kynurenic acid impair cognitive flexibility in adults: reversal with galantamine. (63 citations)
- Elevated levels of kynurenic acid during gestation produce neurochemical, morphological, and cognitive deficits in adulthood: implications for schizophrenia. (56 citations)
- Targeting Kynurenine Aminotransferase II in Psychiatric Diseases: Promising Effects of an Orally Active Enzyme Inhibitor (50 citations)
In his most recent research, the most cited papers focused on:
- Dopamine
- Internal medicine
- Neuroscience
John P. Bruno mainly investigates Kynurenic acid, Kynurenine, Internal medicine, Endocrinology and Morris water navigation task.
John P. Bruno interconnects Prefrontal cortex, Stimulation, Neuroscience and Nicotinic agonist in the investigation of issues within Kynurenic acid.
John P. Bruno combines subjects such as Glutamate receptor, Forebrain, Microdialysis and Cognitive flexibility with his study of Prefrontal cortex.
Neuroscience is often connected to Schizophrenia in his work.
The study of Hippocampal formation and Hippocampus are components of his Morris water navigation task research.
His Enzyme inhibitor research overlaps with Kynurenine—oxoglutarate transaminase, Kynurenine aminotransferase II, Psychiatry, Dopaminergic and Cholinergic.
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