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Jean-Jacques Soghomonian

Jean-Jacques Soghomonian

D-Index & Metrics

Neuroscience

D-Index
35
Citations
5154
World Ranking
9187
National Ranking
3882

Overview

Jean-Jacques Soghomonian is affiliated with Boston University in the United States. The research focus centers on neuroscience and medicine, with specific attention to cognitive neuroscience, neurology, and clinical psychology. Their work frequently explores topics related to autism spectrum disorder research, neurological disorders and treatments, obsessive-compulsive spectrum disorders, and functional brain connectivity studies.

The scientist has contributed to several publications, primarily in the journal Frontiers in Cellular Neuroscience. Among the notable papers are "Increased Dopamine Type 2 Gene Expression in the Dorsal Striatum in Individuals With Autism Spectrum Disorder Suggests Alterations in Indirect Pathway Signaling and Circuitry" published in 2020, and "The cortico-striatal circuitry in autism-spectrum disorders: a balancing act" published in 2024.

Frequent co-authors collaborating with Jean-Jacques Soghomonian include:

  • Cheryl Brandenburg
  • Kunzhong Zhang
  • Ina Sulkaj
  • Brianna Randolph
  • Marissa Kachadoorian

The main fields of study encompass:

  • Neuroscience
  • Medicine

The documented subfields of study are:

  • Cognitive Neuroscience
  • Neurology
  • Clinical Psychology

Key research topics addressed in their work include:

  • Autism Spectrum Disorder Research
  • Neurological disorders and treatments
  • Obsessive-Compulsive Spectrum Disorders
  • Functional Brain Connectivity Studies

Jean-Jacques Soghomonian's research contributes to the understanding of neurobiological mechanisms involved in autism and related neurological conditions, examining pathways such as the cortico-striatal circuitry and neurotransmitter gene expression patterns. Their publications reveal an interest in how alterations at the molecular and circuit levels may relate to clinical symptoms across neurodevelopmental disorders.

Best Publications

  • Two isoforms of glutamate decarboxylase: why?

    Jean-Jacques Soghomonian;David L. Martin

  • Decreased GAD67 mRNA levels in cerebellar Purkinje cells in autism: pathophysiological implications

    Jane Yip;Jean-Jacques Soghomonian;Gene J. Blatt

  • A novel neuronal P2x ATP receptor ion channel with widespread distribution in the brain

    P Seguela;A Haghighi;JJ Soghomonian;E Cooper

  • High-Dose Methamphetamine Acutely Activates the Striatonigral Pathway to Increase Striatal Glutamate and Mediate Long-Term Dopamine Toxicity

    Karla A. Mark;Jean-Jacques Soghomonian;Bryan K. Yamamoto

  • Serotonin innervation in adult rat neostriatum. II. Ultrastructural features: a radioautographic and immunocytochemical study.

    Jean-Jacques Soghomonian;Laurent Descarries;Kenneth C. Watkins

  • Preproenkephalin mRNA expression in the caudate-putamen of MPTP monkeys after chronic treatment with the D2 agonist U91356A in continuous or intermittent mode of administration: comparison with L-DOPA therapy.

    Marc Morissette;Martin Goulet;Jean-Jacques Soghomonian;Pierre J Blanchet

  • Ultrastructural analysis of the serotonin hyperinnervation in adult rat neostriatum following neonatal dopamine denervation with 6-hydroxydopamine.

    Laurent Descarries;Jean-Jacques Soghomonian;Sylvia Garcia;Guy Doucet

  • Decreased GAD65 mRNA levels in select subpopulations of neurons in the cerebellar dentate nuclei in autism: an in situ hybridization study.

    Jane Yip;Jean Jacques Soghomonian;Gene J. Blatt

  • AMPA and NMDA Glutamate Receptor Subunits in Midbrain Dopaminergic Neurons in the Squirrel Monkey: An Immunohistochemical andIn Situ Hybridization Study

    Maryse Paquet;Maryse Paquet;Martine Tremblay;Jean-Jacques Soghomonian;Yoland Smith;Yoland Smith

  • Effects of nigrostriatal lesions on the levels of messenger RNAs encoding two isoforms of glutamate decarboxylase in the globus pallidus and entopeduncular nucleus of the rat

    Jean‐Jacques Soghomonian;Marie‐Francoise Chesselet

  • Messenger RNAs encoding glutamate-decar☐ylases are differentially affected by nigrostriatal lesions in subpopulations of striatal neurons

    Jean-Jacques Soghomonian;Cathleen Gonzales;Marie-Françoise Chesselet

  • Increased GAD67 mRNA expression in cerebellar interneurons in autism: implications for Purkinje cell dysfunction.

    Jane Yip;Jean-Jacques Soghomonian;Gene J. Blatt

  • Comparative distribution of messenger RNAs encoding glutamic acid decarboxylases (Mr 65,000 and Mr 67,000) in the basal ganglia of the rat.

    M. Mercugliano;J.-J. Soghomonian;Y. Qin;H. Q. Nguyen

  • Serotonin innervation in adult rat neostriatum. I. Quantified regional distribution.

    Jean-Jacques Soghomonian;Guy Doucet;Laurent Descarries

  • Changes of D1 and D2 receptors in adult rat neostriatum after neonatal dopamine denervation: quantitative data from ligand binding, in situ hybridization and iontophoresis.

    F. Radja;M. El Mansari;J.-J. Soghomonian;K.M. Dewar

  • Increased glutamate decarboxylase mRNA levels in the striatum and pallidum of MPTP-treated primates

    Jean-Jacques Soghomonian;Sophie Pedneault;Gabrielle Audet;Andre Parent

  • Morphology of Central Serotonin Neurons

    Laurent Descarries;Marie Andrée Audet;Guy Doucet;Sylvia Garcia

  • Glutamate decarboxylase (GAD67 and GAD65) gene expression is increased in a subpopulation of neurons in the putamen of Parkinsonian monkeys.

    Jean-Jacques Soghomonian;Nathalie Laprade

  • Elevation of dopamine D2 but not D1 receptors in adult rat neostriatum after neonatal 6-hydroxydopamine denervation.

    K.M. Dewar;J.-J. Soghomonian;J.P. Bruno;L. Descarries

  • Pathophysiology of L-dopa-induced dyskinesias.

    P. J. Bedard;P. J. Blanchet;D. Levesque;J.-J. Soghomonian

Frequent Co-Authors

Gene J. Blatt
Gene J. Blatt Hussman Institute for Autism
Laurent Descarries
Laurent Descarries University of Montreal
Yoland Smith
Yoland Smith Emory University
John P. Bruno
John P. Bruno The Ohio State University
Paul J. Bédard
Paul J. Bédard Université Laval
Tomás A. Reader
Tomás A. Reader University of Montreal
André Parent
André Parent Université Laval
Marc Morissette
Marc Morissette Université Laval
Frédéric Calon
Frédéric Calon Université Laval
R. Christopher Pierce
R. Christopher Pierce Rutgers, The State University of New Jersey

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