What is he best known for?
The fields of study he is best known for:
His scientific interests lie mostly in DNA ligase, DNA repair, Nucleotide excision repair, Molecular biology and DNA clamp.
His research integrates issues of Processivity, Polymerase and Cell biology in his study of DNA ligase.
His DNA repair study deals with DNA damage intersecting with Exonuclease and Primase.
His Molecular biology study incorporates themes from Base excision repair, AP endonuclease, DNA glycosylase and AP site.
His DNA clamp research is multidisciplinary, incorporating elements of Okazaki fragments, DNA polymerase II, HMG-box and DNA replication.
His research integrates issues of DNA polymerase delta and DNA polymerase I in his study of Okazaki fragments.
His most cited work include:
- AP endonuclease-independent DNA base excision repair in human cells (372 citations)
- AP endonuclease-independent DNA base excision repair in human cells (372 citations)
- Reconstitution of 5'-directed human mismatch repair in a purified system. (304 citations)
What are the main themes of his work throughout his whole career to date?
Alan E. Tomkinson spends much of his time researching DNA ligase, DNA repair, Molecular biology, DNA replication and Biochemistry.
His DNA ligase research incorporates themes from DNA polymerase mu, DNA clamp and Cell biology.
His DNA repair research is multidisciplinary, incorporating perspectives in Cancer research and DNA damage.
His research in Molecular biology intersects with topics in Replication protein A, Non-homologous end joining, Replication factor C, DNA mismatch repair and DNA ligase activity.
His DNA replication study integrates concerns from other disciplines, such as DNA polymerase delta and Proliferating cell nuclear antigen.
His Base excision repair research includes elements of Computational biology and AP site.
He most often published in these fields:
- DNA ligase (69.47%)
- DNA repair (53.68%)
- Molecular biology (47.37%)
What were the highlights of his more recent work (between 2013-2021)?
- DNA ligase (69.47%)
- Cell biology (24.21%)
- DNA repair (53.68%)
In recent papers he was focusing on the following fields of study:
DNA ligase, Cell biology, DNA repair, DNA replication and DNA are his primary areas of study.
The DNA ligase study combines topics in areas such as DDB1 and LIG4.
Within one scientific family, Alan E. Tomkinson focuses on topics pertaining to DNA repair protein XRCC4 under Cell biology, and may sometimes address concerns connected to Ku80 and Non-homologous end joining.
His studies in DNA repair integrate themes in fields like DNA polymerase mu and Mitochondrial DNA.
His DNA replication research includes themes of Molecular biology, DNA clamp and Proliferating cell nuclear antigen.
His work on Homologous recombination and Polymerase is typically connected to XRCC1 as part of general DNA study, connecting several disciplines of science.
Between 2013 and 2021, his most popular works were:
- Chromosomal Translocations in Human Cells Are Generated by Canonical Nonhomologous End-Joining (208 citations)
- Repair of DNA double-strand breaks by mammalian alternative end-joining pathways (85 citations)
- Mutant FUS causes DNA ligation defects to inhibit oxidative damage repair in Amyotrophic Lateral Sclerosis (64 citations)
In his most recent research, the most cited papers focused on:
Alan E. Tomkinson mainly focuses on DNA ligase, Cell biology, DNA damage, Genetics and DNA replication.
His DNA ligase study is concerned with Biochemistry in general.
Alan E. Tomkinson has included themes like Chromatin and DNA in his Cell biology study.
As part of the same scientific family, Alan E. Tomkinson usually focuses on DNA damage, concentrating on DNA polymerase and intersecting with Genome instability, Cancer cell, Cancer and DNA polymerase II.
He has researched DNA replication in several fields, including Molecular biology, MSH2 and Trinucleotide repeat expansion.
His Molecular biology research is multidisciplinary, relying on both DNA repair, Control of chromosome duplication, Licensing factor and Eukaryotic DNA replication.
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