World's Best Scientists 2026 revealed!

D-Index & Metrics

Neuroscience

D-Index
70
Citations
15476
World Ranking
2542
National Ranking
1201

Medicine

D-Index
70
Citations
15476
World Ranking
20117
National Ranking
10014

Overview

A. Leslie Morrow is affiliated with the University of North Carolina at Chapel Hill in the United States. Their research focuses extensively on neuroscience and medicine, with significant contributions to cellular and molecular neuroscience, behavioral neuroscience, molecular biology, immunology, and physiology.

The scientist's main topics of investigation include stress responses and cortisol, neuroscience and neuropharmacology research, estrogen and related hormone effects, immune response and inflammation, tryptophan and brain disorders, neuroinflammation and neurodegeneration mechanisms, and hormonal regulation and hypertension.

Morrow has authored numerous publications, appearing frequently in venues such as UNC Libraries, Neuropharmacology, Biomolecules, Psychoneuroendocrinology, and Psychopharmacology.

Notable recent papers include the following:

  • Neurosteroid allopregnanolone (3α,5α-THP) inhibits inflammatory signals induced by activated MyD88-dependent toll-like receptors (2021, Translational Psychiatry)
  • Brexanolone therapeutics in post-partum depression involves inhibition of systemic inflammatory pathways (2023, EBioMedicine)
  • Novel neurosteroid therapeutics for post-partum depression: perspectives on clinical trials, program development, active research, and future directions (2023, Neuropsychopharmacology)
  • An isotropic EPI database and analytical pipelines for rat brain resting-state fMRI (2021, NeuroImage)
  • Allopregnanolone Decreases Evoked Dopamine Release Differently in Rats by Sex and Estrous Stage (2021, Frontiers in Pharmacology)

Frequent co-authors in their research include Todd K. O'Buckley, Irina Balan, Giorgia Boero, Patrizia Porcu, and Joyce Besheer.

Best Publications

  • The role of GABA(A) receptors in the acute and chronic effects of ethanol.

    A C Grobin;D B Matthews;L L Devaud;A L Morrow

  • The role of GABA(A) receptors in the acute and chronic effects of ethanol: a decade of progress.

    Sandeep Kumar;Patrizia Porcu;David F. Werner;Douglas B. Matthews

  • Characterization of alpha 1-adrenergic receptor subtypes in rat brain: a reevaluation of [3H]WB4104 and [3H]prazosin binding.

    Unknown

  • Synthesis, metabolism, and pharmacological activity of 3 alpha-hydroxy steroids which potentiate GABA-receptor-mediated chloride ion uptake in rat cerebral cortical synaptoneurosomes.

    Robert H. Purdy;A. Leslie Morrow;James R. Blinn;Steven M. Paul

  • GABAA receptor α1 subunit deletion prevents developmental changes of inhibitory synaptic currents in cerebellar neurons

    Stefano Vicini;Carolyn Ferguson;Kate Prybylowski;Jason Kralic

  • Neuroactive Steroid 3α-Hydroxy-5α-Pregnan-20-One Modulates Electrophysiological and Behavioral Actions of Ethanol

    Margaret J. VanDoren;Douglas B. Matthews;Gregory C. Janis;A. Chistina Grobin

  • Allopregnanolone levels and reactivity to mental stress in premenstrual dysphoric disorder.

    Susan S Girdler;Patricia A Straneva;Kathleen C Light;Cort A Pedersen

  • Steroid hormone metabolites potentiate GABA receptor-mediated chloride ion flux with nanomolar potency.

    A.Leslie Morrow;Peter D. Suzdak;Steven M. Paul

  • Bidirectional alterations of GABA(A) receptor subunit peptide levels in rat cortex during chronic ethanol consumption and withdrawal.

    Leslie L. Devaud;Jean Marc Fritschy;Werner Sieghart;A. Leslie Morrow

  • The role of GABAergic neuroactive steroids in ethanol action, tolerance and dependence.

    A.Leslie Morrow;Margaret J VanDoren;Shannon N Penland;Douglas B Matthews

  • Radioimmunoassay of 3α-hydroxy-5α-pregnan-20-one in rat and human plasma

    Robert H. Purdy;Perry H. Moore;P. Narasimha Rao;Nobuyoshi Hagino

  • Proof-of-concept trial with the neurosteroid pregnenolone targeting cognitive and negative symptoms in schizophrenia.

    Christine E. Marx;Christine E. Marx;Richard S.E. Keefe;Robert W. Buchanan;Robert M Hamer

  • Genetic essential tremor in γ-aminobutyric acidA receptor α1 subunit knockout mice

    Jason E. Kralic;Jason E. Kralic;Hugh E. Criswell;Jessica L. Osterman;Todd K. O’Buckley

  • The Neurosteroid, 3α‐Hydroxy‐5α‐pregnan‐20‐one, Protects against Bicuculline‐Induced Seizures during Ethanol Withdrawal in Rats

    Leslie L. Devaud;Robert H. Purdy;A. Leslie Morrow

  • Molecular and Pharmacological Characterization of GABAA Receptor α1 Subunit Knockout Mice

    J. E. Kralic;E. R. Korpi;T. K. O'Buckley;G. E. Homanics

  • Ethanol regulation of γ-aminobutyric acidA receptors: genomic and nongenomic mechanisms

    Sandeep Kumar;Rebekah L. Fleming;A.Leslie Morrow

  • Stress-induced behavioral depression in the rat is associated with a decrease in GABA receptor-mediated chloride ion flux and brain benzodiazepine receptor occupancy

    Robert C. Drugan;A. Leslie Morrow;Ronit Weizman;Abraham Weizman

  • Chronic ethanol and pentobarbital administration in the rat: effects on GABAA receptor function and expression in brain.

    A.Leslie Morrow;Pascale Montpied;Anne Lingford-Hughes;Steven M. Paul

  • GABRA2 alleles moderate the subjective effects of alcohol, which are attenuated by finasteride.

    Amira Pierucci-Lagha;Jonathan Covault;Richard Feinn;Maggie Nellissery

  • Neuroactive steroids are altered in schizophrenia and bipolar disorder: relevance to pathophysiology and therapeutics.

    Christine E Marx;Christine E Marx;Robert D Stevens;Lawrence J Shampine;Lawrence J Shampine;Veska Uzunova

  • GABAA-Receptor δ subunit knockout mice have multiple defects in behavioral responses to ethanol

    Robert M. Mihalek;Barbara J. Bowers;Jeanne M. Wehner;Jason E. Kralic

Frequent Co-Authors

Douglas B. Matthews
Douglas B. Matthews University of Wisconsin–Eau Claire
Jeffrey A. Lieberman
Jeffrey A. Lieberman Columbia University
Kathleen A. Grant
Kathleen A. Grant Oregon National Primate Research Center
Susan S. Girdler
Susan S. Girdler University of North Carolina at Chapel Hill
Gregg E. Homanics
Gregg E. Homanics University of Pittsburgh
Jean-Marc Fritschy
Jean-Marc Fritschy University of Zurich
Clyde W. Hodge
Clyde W. Hodge University of North Carolina at Chapel Hill
Kathleen C. Light
Kathleen C. Light University of Utah
Werner Sieghart
Werner Sieghart Medical University of Vienna
Lawrence H. Price
Lawrence H. Price Brown University

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