World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
74
Citations
15067
World Ranking
5750
National Ranking
2721

Overview

Reuben P. Siraganian is affiliated with the National Institutes of Health in the United States. Their professional profile reflects an active involvement in scientific research within a prominent national institution.

Although specific data on research papers, coauthors, publication venues, and book publications are not available, this affiliation implies engagement with biomedical or health-related research, consistent with the focus areas typically associated with the National Institutes of Health.

Details on their main fields of study, subfields, or primary research topics have not been provided, which limits precise characterization of their scientific focus. Likewise, no records of awards or honors have been noted.

This profile is based solely on confirmed affiliations and publicly available information, ensuring accuracy without speculation on unconfirmed areas of expertise or scholarly output.

Best Publications

  • IgE‐induced histamine release from rat basophilic leukemia cell lines: isolation of releasing and nonreleasing clones

    Edward L. Barsumian;Chaviva Isersky;Marianne G. Petrino;Reuben P. Siraganian

  • Monomeric IgE stimulates signaling pathways in mast cells that lead to cytokine production and cell survival.

    Janet Kalesnikoff;Michael Huber;Vivian Lam;Jacqueline E Damen

  • Mast cell signal transduction from the high-affinity IgE receptor

    Reuben P Siraganian

  • Refinements in the automated fluorometric histamine analysis system.

    Reuben P. Siraganian

  • Protein-tyrosine kinase p72syk in high affinity IgE receptor signaling. Identification as a component of pp72 and association with the receptor gamma chain after receptor aggregation.

    M. Benhamou;N. J. P. Ryba;H. Kihara;H. Nishikata

  • Tyrosine phosphorylation coupled to IgE receptor-mediated signal transduction and histamine release.

    M Benhamou;J S Gutkind;K C Robbins;R P Siraganian

  • Src homology 2 domains of Syk and Lyn bind to tyrosine-phosphorylated subunits of the high affinity IgE receptor.

    H Kihara;R P Siraganian

  • The Negative Signaling Molecule SH2 Domain-containing Inositol-Polyphosphate 5-Phosphatase (SHIP) Binds to the Tyrosine-phosphorylated β Subunit of the High Affinity IgE Receptor

    Teruaki Kimura;Hiroshi Sakamoto;Ettore Appella;Reuben P. Siraganian

  • Protein tyrosine kinase Syk in mast cell signaling.

    Reuben P Siraganian;Juan Zhang;Katsuhiro Suzuki;Kiyonao Sada

  • New effective gonadotropin releasing hormone antagonists with minimal potency for histamine release in vitro

    Jean E. Rivier;John Porter;Catherine L. Rivier;Marilyn Perrin

  • Phosphorylation of Syk activation loop tyrosines is essential for Syk function. An in vivo study using a specific anti-Syk activation loop phosphotyrosine antibody.

    Juan Zhang;Melvin L. Billingsley;Randall L. Kincaid;Reuben P. Siraganian

  • Protein-tyrosine phosphorylation: an essential component of FcεRI signaling

    Marc Benhamou;Reuben P. Siraganian

  • Mast cell signaling: The role of protein tyrosine kinase Syk, its activation and screening methods for new pathway participants

    Reuben P. Siraganian;Rodrigo O. de Castro;Emilia A. Barbu;Juan Zhang

  • Conformational changes induced in the protein tyrosine kinase p72syk by tyrosine phosphorylation or by binding of phosphorylated immunoreceptor tyrosine-based activation motif peptides.

    T Kimura;H Sakamoto;E Appella;R P Siraganian

  • Destruction of Rabbit Platelets in the Allergic Response of Sensitized Leukocytes I. Demonstration of a Fluid Phase Intermediate

    Reuben P. Siraganian;Abraham G. Osler

  • Mechanism of Histamine Release by Formyl Methionine-Containing Peptides

    Reuben P. Siraganian;William A. Hook

  • Histamine Release and Assay Methods for the Study of Human Allergy

    Reuben P. Siraganian;William A. Hook

  • Human and rat mast cell high-affinity immunoglobulin E receptors: characterization of putative alpha-chain gene products

    A Shimizu;I Tepler;P N Benfey;E H Berenstein

  • Tyrosine phosphorylation of pp125FAK by the aggregation of high affinity immunoglobulin E receptors requires cell adherence.

    M M Hamawy;S E Mergenhagen;R P Siraganian

  • THE PROTEIN-TYROSINE PHOSPHATASE SHP-2 ASSOCIATES WITH TYROSINE-PHOSPHORYLATED ADHESION MOLECULE PECAM-1 (CD31)

    Kenji Sagawa;Teruaki Kimura;Mark Swieter;Reuben P. Siraganian

Frequent Co-Authors

Constance Oliver
Constance Oliver Universidade de São Paulo
Stephan E. Mergenhagen
Stephan E. Mergenhagen National Institutes of Health
Fulton T. Crews
Fulton T. Crews University of North Carolina at Chapel Hill
Fusao Hirata
Fusao Hirata Johns Hopkins University
Julius Axelrod
Julius Axelrod National Institutes of Health
Jean Rivier
Jean Rivier Salk Institute for Biological Studies
Henry Metzger
Henry Metzger National Institutes of Health
Ettore Appella
Ettore Appella National Institutes of Health
Keith C. Robbins
Keith C. Robbins National Institutes of Health
Catherine Rivier
Catherine Rivier Salk Institute for Biological Studies

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Best Scientists Citing Reuben P. Siraganian