What is he best known for?
The fields of study he is best known for:
- Enzyme
- Internal medicine
- Immune system
Donald W. MacGlashan spends much of his time researching Histamine, Immunoglobulin E, Basophil, Internal medicine and Endocrinology.
Donald W. MacGlashan has included themes like Mast cell, Receptor, Leukotriene and Cell biology in his Histamine study.
The concepts of his Receptor study are interwoven with issues in Leukotriene C4 and Liberation.
Immunoglobulin E is the subject of his research, which falls under Immunology.
His work on Omalizumab, Allergy and Allergen as part of general Immunology study is frequently connected to Downregulation and upregulation, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them.
His research in Basophil intersects with topics in Secretion, Stimulation and Interleukin 4.
His most cited work include:
- Down-regulation of Fc(epsilon)RI expression on human basophils during in vivo treatment of atopic patients with anti-IgE antibody. (690 citations)
- Omalizumab-induced reductions in mast cell FcεRI expression and function (344 citations)
- The human recombinant c-kit receptor ligand, rhSCF, induces mediator release from human cutaneous mast cells and enhances IgE-dependent mediator release from both skin mast cells and peripheral blood basophils. (283 citations)
What are the main themes of his work throughout his whole career to date?
Histamine, Immunology, Immunoglobulin E, Basophil and Mast cell are his primary areas of study.
His Histamine study incorporates themes from Molecular biology, Biochemistry and Stimulation.
In most of his Immunology studies, his work intersects topics such as Receptor expression.
His Immunoglobulin E study combines topics from a wide range of disciplines, such as Receptor, Interleukin 4, Antigen and Cell biology.
Donald W. MacGlashan has researched Basophil in several fields, including Secretion, Granulocyte, Leukotriene, Syk and Degranulation.
His study focuses on the intersection of Endocrinology and fields such as Calcium with connections in the field of Extracellular.
He most often published in these fields:
- Histamine (49.81%)
- Immunology (46.30%)
- Immunoglobulin E (46.30%)
What were the highlights of his more recent work (between 2009-2021)?
- Immunology (46.30%)
- Immunoglobulin E (46.30%)
- Basophil (44.75%)
In recent papers he was focusing on the following fields of study:
Donald W. MacGlashan focuses on Immunology, Immunoglobulin E, Basophil, Histamine and Omalizumab.
The Immunoglobulin E study combines topics in areas such as Receptor, Stimulation and Allergy.
His Basophil research is multidisciplinary, incorporating perspectives in Receptor expression and Interleukin 4.
His Histamine research includes elements of Degranulation, Antigen and Syk.
As part of one scientific family, he deals mainly with the area of Omalizumab, narrowing it down to issues related to the Food allergy, and often Basopenia.
The study incorporates disciplines such as Oncology and Parenchyma in addition to Internal medicine.
Between 2009 and 2021, his most popular works were:
- Expression of CD203c and CD63 in human basophils: relationship to differential regulation of piecemeal and anaphylactic degranulation processes (118 citations)
- Kinetics of mast cell, basophil, and oral food challenge responses in omalizumab-treated adults with peanut allergy (102 citations)
- IgE antibody-specific activity in human allergic disease (88 citations)
In his most recent research, the most cited papers focused on:
- Enzyme
- Immune system
- Internal medicine
His primary scientific interests are in Immunology, Basophil, Immunoglobulin E, Histamine and Syk.
His Immunology study which covers Receptor that intersects with Secretion, CD23 and Cell type.
The various areas that he examines in his Basophil study include Mast cell, Interleukin 33, Epitope and Stimulation.
His Mast cell study combines topics in areas such as Eosinophil, Biochemistry and Chronic urticaria.
His work carried out in the field of Histamine brings together such families of science as Omalizumab and Degranulation.
His Syk research also works with subjects such as
- Bruton's tyrosine kinase which is related to area like Autoantibody and Interleukin 4,
- LYN which intersects with area such as Flow cytometry.
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