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Neuroscience

D-Index
55
Citations
14727
World Ranking
4645
National Ranking
402

Overview

Zuner A. Bortolotto is affiliated with the University of Bristol in the United Kingdom. Their research primarily focuses on neuroscience, with a strong emphasis on cellular and molecular neuroscience, cognitive neuroscience, and molecular biology. Additional areas of study include neurology and endocrine and autonomic systems.

The scientist's work spans several main topics, including neuroscience and neuropharmacology research, memory and neural mechanisms, neuroinflammation and neurodegeneration mechanisms, circadian rhythm and melatonin, stress responses and cortisol, tryptophan and brain disorders, and ion channel regulation and function.

Recent publications by Zuner A. Bortolotto include the following:

  • Side-by-side comparison of the effects of Gq- and Gi-DREADD-mediated astrocyte modulation on intracellular calcium dynamics and synaptic plasticity in the hippocampal CA1, 2021, Molecular Brain
  • PKA drives an increase in AMPA receptor unitary conductance during LTP in the hippocampus, 2021, Nature Communications
  • Circadian regulation of hippocampal function is disrupted with corticosteroid treatment, 2023, Proceedings of the National Academy of Sciences
  • The ERK phosphorylation levels in the amygdala predict anxiety symptoms in humans and MEK/ERK inhibition dissociates innate and learned defensive behaviors in rats, 2021, Molecular Psychiatry
  • Differential regulation of STP, LTP and LTD by structurally diverse NMDA receptor subunit-specific positive allosteric modulators, 2021, Neuropharmacology

Zuner A. Bortolotto has collaborated frequently with other researchers in the field. Prominent co-authors include:

  • Graham L. Collingridge
  • John Georgiou
  • Thomas M. Sanderson
  • Elizabeth C. Warburton
  • Stafford L. Lightman

The scientist's work has been published repeatedly in prominent venues, with multiple publications in bioRxiv (Cold Spring Harbor Laboratory) and Neuropharmacology. Other notable publication venues include Molecular Brain, Proceedings of the National Academy of Sciences, and Nature Communications.

Best Publications

  • Review: Cholinergic mechanisms and epileptogenesis. The seizures induced by pilocarpine: A novel experimental model of intractable epilepsy

    Lechoslaw Turski;Chrysanthy Ikonomidou;Waldemar A. Turski;Zuner A. Bortolotto

  • Induction of LTP in the hippocampus needs synaptic activation of glutamate metabotropic receptors

    Zafar I. Bashir;Zuner A. Bortolotto;Ceri H. Davies;Nicola Berretta

  • LTP inhibits LTD in the hippocampus via regulation of GSK3beta.

    Stéphane Peineau;Changiz Taghibiglou;Clarrisa Bradley;Tak Pan Wong

  • Long-term effects of pilocarpine in rats: structural damage of the brain triggers kindling and spontaneous recurrent seizures.

    E. A. Cavalheiro;J. P. Leite;Z. A. Bortolotto;W. A. Turski

  • Transient incorporation of native GluR2-lacking AMPA receptors during hippocampal long-term potentiation

    Karen Plant;Kenneth A Pelkey;Zuner A Bortolotto;Daiju Morita;Daiju Morita

  • A molecular switch activated by metabotropic glutamate receptors regulates induction of long-term potentiation.

    Z. A. Bortolotto;Z. I. Bashir;C. H. Davies;G. L. Collingridge

  • Seizures produced by pilocarpine in mice: A behavioral, electroencephalographic and morphological analysis

    Waldemar A. Turski;Esper A. Cavalheiro;Zuner A. Bortolotto;Luiz M. Mello

  • PDZ Proteins Interacting with C-Terminal GluR2/3 Are Involved in a PKC-Dependent Regulation of AMPA Receptors at Hippocampal Synapses

    Michael I. Daw;Ramesh Chittajallu;Zuner A. Bortolotto;Kumlesh K. Dev

  • Kainate receptors are involved in synaptic plasticity

    Zuner A. Bortolotto;Vernon R. J. Clarke;Caroline M. Delany;Michael C. Parry

  • Differential roles of NR2A and NR2B-containing NMDA receptors in LTP and LTD in the CA1 region of two-week old rat hippocampus

    Thomas E. Bartlett;Neil J. Bannister;Valerie J. Collett;Sheila L. Dargan

  • The role of JAK-STAT signaling within the CNS

    Celine S Nicolas;Mascia Amici;Zuner A Bortolotto;Andrew J Doherty

  • Characterisation of LTP induced by the activation of glutamate metabotropic receptors in area CA1 of the hippocampus

    Zuner A. Bortolotto;Graham L. Collingridge

  • The susceptibility of rats to pilocarpine-induced seizures is age-dependent.

    Esper A. Cavalheiro;Delrio F. Silva;Waldemar A. Turski;Lineu S. Calderazzo-Filho

  • Spontaneous recurrent seizures in rats: an experimental model of partial epilepsy.

    J.P. Leite;Z.A. Bortolotto;E.A. Cavalheiro

  • Roles of metabotropic glutamate receptors in LTP and LTD in

    Zuner A Bortolotto;Stephen M Fitzjohn;Graham L Collingridge

  • The role of GSK-3 in synaptic plasticity.

    Stephane A J Peineau;C Bradley;C Taghibiglou;Andrew J Doherty

  • The NMDA receptor as a target for cognitive enhancement.

    Graham L. Collingridge;Arturas Volianskis;Neil Bannister

  • The JAK/STAT Pathway Is Involved in Synaptic Plasticity

    Céline S. Nicolas;Stéphane Peineau;Stéphane Peineau;Stéphane Peineau;Mascia Amici;Zsolt Csaba;Zsolt Csaba

  • Long-term potentiation and the role of N-methyl-D-aspartate receptors.

    Arturas Volianskis;Morten S. Jensen;Zuner A. Bortolotto

  • A critical role of a facilitatory presynaptic kainate receptor in mossy fiber LTP.

    Sari E Lauri;Zuner A Bortolotto;David Bleakman;Paul L Ornstein

  • Current protocols in neuroscience

    Zuner A Bortolotto;Mascia Amici;WW Anderson;JT Isaac

Frequent Co-Authors

Graham L. Collingridge
Graham L. Collingridge Lunenfeld-Tanenbaum Research Institute
Esper A. Cavalheiro
Esper A. Cavalheiro Federal University of Sao Paulo
Bong-Kiun Kaang
Bong-Kiun Kaang Seoul National University
Min Zhuo
Min Zhuo University of Toronto
John T.R. Isaac
John T.R. Isaac Johnson & Johnson (United States)
Robert Nisticò
Robert Nisticò University of Rome Tor Vergata
Zafar I. Bashir
Zafar I. Bashir University of Bristol
Ilse Smolders
Ilse Smolders Vrije Universiteit Brussel
Roger Walz
Roger Walz Universidade Federal de Santa Catarina
Chrysanthy Ikonomidou
Chrysanthy Ikonomidou University of Wisconsin–Madison

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