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Massimo Avoli

Massimo Avoli

D-Index & Metrics

Neuroscience

D-Index
85
Citations
24494
World Ranking
1343
National Ranking
71

Overview

Massimo Avoli is affiliated with McGill University in Canada and has contributed extensively to the fields of Neuroscience and Biochemistry, Genetics and Molecular Biology. Their research spans several specialized subfields including Cellular and Molecular Neuroscience, Cognitive Neuroscience, Molecular Biology, Cell Biology, and Genetics.

Their work covers a range of topics such as Neuroscience and Neuropharmacology Research, Photoreceptor and Optogenetics Research, Ion Channel Regulation and Function, Genetics and Neurodevelopmental Disorders, Memory and Neural Mechanisms, Microtubule and Mitosis Dynamics, and Functional Brain Connectivity Studies.

Among recent publications, Massimo Avoli has authored or co-authored the following papers:

  • Excitatory neuron-specific suppression of the integrated stress response contributes to autism-related phenotypes in fragile X syndrome (2023, Neuron)
  • Ligand-gated mechanisms leading to ictogenesis in focal epileptic disorders (2023, Neurobiology of Disease)
  • Specific quinone reductase 2 inhibitors reduce metabolic burden and reverse Alzheimer's disease phenotype in mice (2023, Journal of Clinical Investigation)
  • Modulation of in vitro epileptiform activity by optogenetic stimulation of parvalbumin-positive interneurons (2022, Journal of Neurophysiology)
  • Ictal activity is sustained by the estrogen receptor β during the estrous cycle (2024, Current Research in Neurobiology)

Frequently collaborating with other researchers, Avoli's frequent co-authors include Maxime Lévesque, Siyan Wang, Thomas M. Durcan, Graziella Di Cristo, and Heidi Cope. Their contributions have appeared in several venues such as Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature, bioRxiv (Cold Spring Harbor Laboratory), Neuron, Neurobiology of Disease, and Journal of Clinical Investigation.

Best Publications

  • The pilocarpine model of temporal lobe epilepsy.

    Giulia Curia;Daniela Longo;Giuseppe Biagini;Roland S.G. Jones

  • The kainic acid model of temporal lobe epilepsy

    Maxime Lévesque;Massimo Avoli;Massimo Avoli

  • Jasper's basic mechanisms of the epilepsies

    Jeffrey L Noebels;Massimo Avoli;Michael A Rogawski;Richard W Olsen

  • Network and pharmacological mechanisms leading to epileptiform synchronization in the limbic system in vitro.

    Massimo Avoli;Margherita D’Antuono;Jacques Louvel;Rüdiger Köhling

  • Voltage-gated sodium channels as therapeutic targets in epilepsy and other neurological disorders

    Massimo Mantegazza;Giulia Curia;Giuseppe Biagini;David S Ragsdale

  • CA3-Driven Hippocampal-Entorhinal Loop Controls Rather than Sustains In Vitro Limbic Seizures

    Michaela Barbarosie;Massimo Avoli

  • GABA and Epileptogenesis

    Richard W. Olsen;Massimo Avoli

  • Mechanisms of physiological and epileptic HFO generation.

    John G.R. Jefferys;Liset Menendez de la Prida;Fabrice Wendling;Anatol Bragin

  • Physiology and pharmacology of epileptiform activity induced by 4-aminopyridine in rat hippocampal slices

    P. Perreault;M. Avoli

  • Synchronous GABA-Mediated Potentials and Epileptiform Discharges in the Rat Limbic System In Vitro

    Massimo Avoli;Michaela Barbarosie;Anne Lücke;Takeki Nagao

  • Sodium channels as molecular targets for antiepileptic drugs

    David S Ragsdale;Massimo Avoli;Massimo Avoli

  • GABAergic synchronization in the limbic system and its role in the generation of epileptiform activity.

    Massimo Avoli;Marco de Curtis

  • Topiramate attenuates voltage-gated sodium currents in rat cerebellar granule cells.

    Cristina Zona;Maria Teresa Ciotti;Massimo Avoli

  • Animal models of temporal lobe epilepsy following systemic chemoconvulsant administration

    Maxime Lévesque;Massimo Avoli;Christophe Bernard

  • Cortical dysplasia An immunocytochemical study of three patients

    R. Spreafico;G. Battaglia;P. Arcelli;F. Andermann

  • Cellular and molecular mechanisms of epilepsy in the human brain.

    Massimo Avoli;Massimo Avoli;Jacques Louvel;René Pumain;Rüdiger Köhling

  • 4-aminopyridine-induced epileptiform activity and a GABA-mediated long- lasting depolarization in the rat hippocampus

    Paul Perreault;Massimo Avoli

  • Downregulation of Tonic GABAergic Inhibition in a Mouse Model of Fragile X Syndrome

    Giulia Curia;Thomas Papouin;Thomas Papouin;Philippe Séguéla;Massimo Avoli;Massimo Avoli

  • Facilitation of epileptic activity during sleep is mediated by high amplitude slow waves

    Birgit Frauscher;Birgit Frauscher;Nicolás von Ellenrieder;Nicolás von Ellenrieder;Taissa Ferrari-Marinho;Massimo Avoli

  • An analysis of penicillin-induced generalized spike and wave discharges using simultaneous recordings of cortical and thalamic single neurons.

    M. Avoli;P. Gloor;G. Kostopoulos;J. Gotman

  • Neuronal Synchronization and Thalamocortical Rhythms in Sleep, Wake and Epilepsy -- Jasper's Basic Mechanisms of the Epilepsies

    Noebels Jl;Avoli M;Rogawski Ma;Olsen Rw

Frequent Co-Authors

Michael A. Rogawski
Michael A. Rogawski University of California, Davis
Antonio V. Delgado-Escueta
Antonio V. Delgado-Escueta University of California, Los Angeles
Giuseppe Biagini
Giuseppe Biagini University of Modena and Reggio Emilia
George K. Kostopoulos
George K. Kostopoulos University of Patras
Jean Gotman
Jean Gotman Montreal Neurological Institute and Hospital
Pierre Gloor
Pierre Gloor Montreal Neurological Institute and Hospital
Donatella Mattia
Donatella Mattia Sapienza University of Rome
Rüdiger Köhling
Rüdiger Köhling University of Rostock
Hiroto Kawasaki
Hiroto Kawasaki University of Iowa
Sylvain Williams
Sylvain Williams McGill University

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