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Neuroscience

D-Index
60
Citations
12667
World Ranking
3847
National Ranking
42

Overview

Ilse Smolders is affiliated with the Vrije Universiteit Brussel in Belgium and has a research focus primarily in the fields of Neuroscience and Biochemistry, Genetics and Molecular Biology. Their work encompasses specialized areas including Cellular and Molecular Neuroscience, Molecular Biology, Physiology, Endocrine and Autonomic Systems, and Neurology.

The volume of their research outputs shows a concentration on topics such as Neuroscience and Neuropharmacology Research, Circadian rhythm and melatonin, Neuroinflammation and Neurodegeneration Mechanisms, Epilepsy research and treatment, Alzheimer's disease research and treatments, Receptor Mechanisms and Signaling, and Photochromic and Fluorescence Chemistry.

Smolders has published significant papers in recent years including:

  • Role of the GLUT1 Glucose Transporter in Postnatal CNS Angiogenesis and Blood-Brain Barrier Integrity (2020, Circulation Research)
  • Melatonin levels in the Alzheimer's disease continuum: a systematic review (2021, Alzheimer s Research & Therapy)
  • Side-by-side comparison of the effects of Gq- and Gi-DREADD-mediated astrocyte modulation on intracellular calcium dynamics and synaptic plasticity in the hippocampal CA1 (2021, Molecular Brain)
  • Astrocytic Connexin43 Channels as Candidate Targets in Epilepsy Treatment (2020, Biomolecules)
  • Chemogenetic modulation of astrocytes and microglia: State-of-the-art and implications in neuroscience (2023, Glia)

Frequent publishing venues for Smolders include:

  • Epilepsia
  • International Journal of Molecular Sciences
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Alzheimer s Research & Therapy
  • Brain stimulation

There is collaboration with several frequent co-authors, among them:

  • Dimitri De Bundel
  • Ann Van Eeckhaut
  • Najat Aourz
  • Sebastiaan Engelborghs
  • Wissal Allaoui

Overall, Smolders' research contributions span multiple intersecting domains within neuroscience and molecular biology, encompassing both fundamental physiological processes and applied neurological disorder studies.

Best Publications

  • The cystine/glutamate antiporter system xc- in health and disease: From molecular mechanisms to novel therapeutic opportunities

    Jan Lewerenz;Sandra J. Hewett;Ying Huang;Maria Lambros

  • Kainate receptors are involved in synaptic plasticity

    Zuner A. Bortolotto;Vernon R. J. Clarke;Caroline M. Delany;Michael C. Parry

  • Increased hippocampal noradrenaline is a biomarker for efficacy of vagus nerve stimulation in a limbic seizure model

    Robrecht Raedt;Ralph Clinckers;Lies Mollet;Kristl Vonck

  • Validation of the Zebrafish Pentylenetetrazol Seizure Model: Locomotor versus Electrographic Responses to Antiepileptic Drugs

    Tatiana Afrikanova;Ann-Sophie K. Serruys;Olivia E. M. Buenafe;Ralph Clinckers

  • Endurance training effects on neurotransmitter release in rat striatum: an in vivo microdialysis study.

    R. Meeusen;I. Smolders;S. Sarre;K. De Meirleir

  • Astroglial CB1 Receptors Determine Synaptic D-Serine Availability to Enable Recognition Memory.

    Laurie M. Robin;José F. Oliveira da Cruz;Valentin C. Langlais;Mario Martin-Fernandez

  • Role of the GLUT1 Glucose Transporter in Postnatal CNS Angiogenesis and Blood-Brain Barrier Integrity

    Koen Veys;Zheng Fan;Moheb Ghobrial;Moheb Ghobrial;Ann Bouché

  • Loss of system x(c)- does not induce oxidative stress but decreases extracellular glutamate in hippocampus and influences spatial working memory and limbic seizure susceptibility.

    Dimitri De Bundel;Anneleen Schallier;Ellen Loyens;Ruani Fernando

  • NMDA receptor‐mediated pilocarpine‐induced seizures: characterization in freely moving rats by microdialysis

    Ilse Julia Smolders;G.m. Khan;Jacqueline Manil;Guy Ebinger

  • Tonic GABA-ergic modulation of striatal dopamine release studied by in vivo microdialysis in the freely moving rat.

    Ilse Julia Smolders;Nina De Klippel;Sophie Sarre;Guy Ebinger

  • Anticonvulsant action of hippocampal dopamine and serotonin is independently mediated by D2 and 5‐HT1A receptors

    Ralph Clinckers;Ilse Julia Smolders;Alfred Meurs;Guy Ebinger

  • Antagonists of GLU K5 -containing kainate receptors prevent pilocarpine-induced limbic seizures

    Ilse Smolders;Zuner A. Bortolotto;Vernon R. J. Clarke;Ruth Warre

  • Impaired islet function in commonly used transgenic mouse lines due to human growth hormone minigene expression.

    Bas Brouwers;Geoffroy de Faudeur;Anna B Osipovich;Lotte Goyvaerts

  • Pharmacological Analysis of the Anti-epileptic Mechanisms of Fenfluramine in scn1a Mutant Zebrafish.

    Jo Sourbron;Ilse Smolders;Peter de Witte;Lieven Lagae

  • Seizure activity and changes in hippocampal extracellular glutamate, GABA, dopamine and serotonin

    Alfred Meurs;Ralph Clinckers;Guy Ebinger;Yvette Michotte

  • Dopaminergic neurons of system x(c)⁻-deficient mice are highly protected against 6-hydroxydopamine-induced toxicity.

    Ann Massie;Anneleen Schallier;Seong Woong Kim;Ruani Fernando

  • The analysis of excitatory, inhibitory and other amino acids in rat brain microdialysates using microbore liquid chromatography

    I. Smolders;S. Sarre;Y. Michotte;G. Ebinger

  • Region- and age-specific changes in glutamate transport in the AβPP23 mouse model for Alzheimer's disease.

    Anneleen Schallier;Ilse Julia Smolders;Debby Van Dam;Ellen Loyens

  • Serotonergic Modulation as Effective Treatment for Dravet Syndrome in a Zebrafish Mutant Model

    Jo Sourbron;Henning Schneider;Angéla Kecskés;Yusu Liu

  • Muscarinic modulation of striatal dopamine, glutamate, and GABA release, as measured with in vivo microdialysis.

    Ilse Julia Smolders;Liesbeth Bogaert;Guy Ebinger;Yvette Michotte

Frequent Co-Authors

Yvette Michotte
Yvette Michotte Vrije Universiteit Brussel
Siew Yeen Chai
Siew Yeen Chai Monash University
Paul Boon
Paul Boon Ghent University
Kristl Vonck
Kristl Vonck Ghent University
Giuseppe Di Giovanni
Giuseppe Di Giovanni Magna Graecia University
Graham L. Collingridge
Graham L. Collingridge Lunenfeld-Tanenbaum Research Institute
Zuner A. Bortolotto
Zuner A. Bortolotto University of Bristol
Wytse J. Wadman
Wytse J. Wadman University of Amsterdam
Michael J. O'Neill
Michael J. O'Neill Eli Lilly (United States)

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