Peter de Witte

Best Publications

• A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death.

  Abhishek D Garg;Dmitri V Krysko;Tom Verfaillie;Agnieszka Kaczmarek

  805
  Citations

• Liposomes for photodynamic therapy.

  Annelies S L Derycke;Peter A M de Witte

  685
  Citations

• Hypericin in cancer treatment: more light on the way.

  Patrizia Agostinis;Annelies Vantieghem;Wilfried Merlevede;Peter A.M. de Witte

  597
  Citations

• Molecular and Translational Classifications of DAMPs in Immunogenic Cell Death

  Abhishek D. Garg;Lorenzo Galluzzi;Lionel Apetoh;Lionel Apetoh;Thais Baert

  416
  Citations

• The activation of the c-Jun N-terminal kinase and p38 mitogen-activated protein kinase signaling pathways protects HeLa cells from apoptosis following photodynamic therapy with hypericin.

  Zerihun Assefa;Annelies Vantieghem;Wim Declercq;Peter Vandenabeele

  305
  Citations

• Validation of the Zebrafish Pentylenetetrazol Seizure Model: Locomotor versus Electrographic Responses to Antiepileptic Drugs

  Tatiana Afrikanova;Ann-Sophie K. Serruys;Olivia E. M. Buenafe;Ralph Clinckers

  294
  Citations

• De Novo Loss-of-Function Mutations in CHD2 Cause a Fever-Sensitive Myoclonic Epileptic Encephalopathy Sharing Features with Dravet Syndrome

  Arvid Suls;Johanna A. Jaehn;Angela Kecskés;Yvonne Weber

  263
  Citations

• Mutations in STX1B, encoding a presynaptic protein, cause fever-associated epilepsy syndromes.

  Julian Schubert;Aleksandra Siekierska;Mélanie Langlois;Patrick May

  222
  Citations

• Evaluation of 14 Organic Solvents and Carriers for Screening Applications in Zebrafish Embryos and Larvae

  Jan Maes;Lien Verlooy;Olivia E. Buenafe;Peter A. M. de Witte

  222
  Citations

• Hypericin-induced photosensitization of HeLa cells leads to apoptosis or necrosis Involvement of cytochrome c and procaspase-3 activation in the mechanism of apoptosis

  Annelies Vantieghem;Zerihun Assefa;Peter Vandenabeele;Wim Declercq

  191
  Citations

• Cytotoxicity of some medicinal plant extracts used in Tanzanian traditional medicine.

  Appolinary Kamuhabwa;Charles Nshimo;Peter de Witte

  171
  Citations

• Targeting of the photocytotoxic compound AlPcS4 to Hela cells by transferrin conjugated PEG-liposomes.

  Antoon Gijsens;Annelies Derycke;Ludwig Missiaen;Dirk De Vos

  171
  Citations

• Up-regulation of cyclooxygenase-2 and apoptosis resistance by p38 MAPK in hypericin-mediated photodynamic Therapy of human cancer cells

  Nico Hendrickx;Cédric Volanti;Ugo Moens;Ole Morten Seternes

  166
  Citations

• The Multifaceted Photocytotoxic Profile of Hypericin

  Theodossis A. Theodossiou;John S. Hothersall;Peter A. De Witte;Alexandros Pantos

  166
  Citations

• Phosphorylation of Bcl-2 in G2/M phase-arrested cells following photodynamic therapy with hypericin involves a CDK1-mediated signal and delays the onset of apoptosis

  Annelies Vantieghem;Yan Xu;Zerihun Assefa;Jacques Piette

  164
  Citations

• Transferrin-conjugated liposome targeting of photosensitizer AlPcS4 to rat bladder carcinoma cells.

  Annelies S. L. Derycke;Appolinary Kamuhabwa;Antoon Gijsens;Tania Roskams

  159
  Citations

• Induction of heme-oxygenase 1 requires the p38MAPK and PI3K pathways and suppresses apoptotic cell death following hypericin-mediated photodynamic therapy.

  Silvia Kocanova;Esther Buytaert;Jean-Yves Matroule;Jacques Piette

  155
  Citations

• A robust human norovirus replication model in zebrafish larvae

  Jana Van Dycke;Annelii Ny;Nádia Conceição-Neto;Jan Maes

  154
  Citations

• Fishing for drugs from nature: zebrafish as a technology platform for natural product discovery.

  Alexander D. Crawford;Camila V. Esguerra;Peter A. M. de Witte

  143
  Citations

• Fluorescence detection of flat bladder carcinoma in situ after intravesical instillation of hypericin.

  Marie-Ange D’Hallewin;Peter A. De Witte;Etienne Waelkens;Wilfried Merlevede

  142
  Citations