D-Index & Metrics Best Publications
Wilfried Merlevede

Wilfried Merlevede

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 57 Citations 9,423 206 World Ranking 9562 National Ranking 174

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • Phosphorylation

Wilfried Merlevede mainly investigates Biochemistry, Molecular biology, Phosphatase, Phosphorylation and Hypericin. Wilfried Merlevede has included themes like Hypericum perforatum and Skeletal muscle in his Biochemistry study. His Molecular biology study incorporates themes from Epidermal growth factor, HaCaT, Apoptosis, Cytochrome c and Protein subunit.

As a part of the same scientific study, Wilfried Merlevede usually deals with the Protein subunit, concentrating on Peptide sequence and frequently concerns with Sequence analysis and Complementary DNA. The various areas that Wilfried Merlevede examines in his Phosphatase study include Glycogen phosphorylase, Dialysis, ATP synthase and Adenosine triphosphate. He focuses mostly in the field of Hypericin, narrowing it down to topics relating to HeLa and, in certain cases, Cytotoxicity, Cell biology and Neutral red.

His most cited work include:

  • Hypericin in cancer treatment: more light on the way. (348 citations)
  • alpha- and beta-forms of the 65-kDa subunit of protein phosphatase 2A have a similar 39 amino acid repeating structure. (204 citations)
  • The activation of the c-Jun N-terminal kinase and p38 mitogen-activated protein kinase signaling pathways protects HeLa cells from apoptosis following photodynamic therapy with hypericin. (197 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Biochemistry, Phosphatase, Molecular biology, phosphatase and Phosphorylation. His studies in Adenosine triphosphate, Glycogen phosphorylase, Enzyme activator, Phosphorylase kinase and Enzyme are all subfields of Biochemistry research. His study in Phosphatase is interdisciplinary in nature, drawing from both Protein subunit and Protein kinase A.

His Molecular biology research incorporates elements of Protein phosphatase 2, Protein tyrosine phosphatase, Kinase activity, Peptide sequence and Acid phosphatase. Adrenal cortex is closely connected to Phosphoric monoester hydrolases in his research, which is encompassed under the umbrella topic of phosphatase. His studies in Phosphorylation integrate themes in fields like Microtubule-associated protein and Calmodulin.

He most often published in these fields:

  • Biochemistry (74.46%)
  • Phosphatase (48.37%)
  • Molecular biology (44.57%)

What were the highlights of his more recent work (between 1996-2005)?

  • Molecular biology (44.57%)
  • Hypericin (10.87%)
  • Protein phosphatase 2 (17.93%)

In recent papers he was focusing on the following fields of study:

Wilfried Merlevede focuses on Molecular biology, Hypericin, Protein phosphatase 2, Biochemistry and Cell biology. His Molecular biology research is multidisciplinary, incorporating perspectives in Epidermal growth factor, PHOSPHOTYROSYL PHOSPHATASE ACTIVATOR, Gene, Cyclin-dependent kinase complex and Cyclin D. He interconnects Cancer research, Apoptosis, Phototoxicity, Cytotoxicity and Hypericum perforatum in the investigation of issues within Hypericin.

His Protein phosphatase 2 study introduces a deeper knowledge of Phosphatase. His Phosphatase research includes themes of Protein tyrosine phosphatase, Alternative splicing, Exon, cDNA library and Intron. His research integrates issues of Cyclin-dependent kinase and Cytochrome c in his study of Cell biology.

Between 1996 and 2005, his most popular works were:

  • Hypericin in cancer treatment: more light on the way. (348 citations)
  • The activation of the c-Jun N-terminal kinase and p38 mitogen-activated protein kinase signaling pathways protects HeLa cells from apoptosis following photodynamic therapy with hypericin. (197 citations)
  • The MgATP-Dependent Protein Phosphatase and Protein Phosphatase 1 Have Identical Substrate Specificities (173 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Phosphorylation

His primary scientific interests are in Molecular biology, Hypericin, HeLa, Cell biology and Protein kinase A. His Molecular biology research includes elements of Protein phosphatase 2, Epidermal growth factor, HaCaT and Apoptosis, Cytochrome c. His Hypericin study combines topics in areas such as Biochemistry, Radiation therapy and Carcinoma.

In general Biochemistry study, his work on Programmed cell death often relates to the realm of Cancer cell, thereby connecting several areas of interest. His Protein kinase A research incorporates themes from Signal transduction and Protein kinase C. His Phosphatase study integrates concerns from other disciplines, such as Glycogen phosphorylase, Phosphorylase kinase and Acid phosphatase.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Hypericin in cancer treatment: more light on the way.

Patrizia Agostinis;Annelies Vantieghem;Wilfried Merlevede;Peter A.M. de Witte.
The International Journal of Biochemistry & Cell Biology (2002)

534 Citations

alpha- and beta-forms of the 65-kDa subunit of protein phosphatase 2A have a similar 39 amino acid repeating structure.

Brian A. Hemmings;Carolyn Adams-Pearson;Francisca Maurer;Peter Mueller.
Biochemistry (1990)

307 Citations

The activation of the c-Jun N-terminal kinase and p38 mitogen-activated protein kinase signaling pathways protects HeLa cells from apoptosis following photodynamic therapy with hypericin.

Zerihun Assefa;Annelies Vantieghem;Wim Declercq;Peter Vandenabeele.
Journal of Biological Chemistry (1999)

297 Citations

Structure of the 55-kDa regulatory subunit of protein phosphatase 2A: evidence for a neuronal-specific isoform

Regina E. Mayer;Peter Hendrix;Peter Cron;Renate Matthies.
Biochemistry (1991)

270 Citations

The MgATP-Dependent Protein Phosphatase and Protein Phosphatase 1 Have Identical Substrate Specificities

Alexander A. Stewart;Brian A. Hemmings;Philip Cohen;Jozef Goris.
FEBS Journal (2005)

263 Citations

ATP x Mg-dependent protein phosphatase from rabbit skeletal muscle. II. Purification of the activating factor and its characterization as a bifunctional protein also displaying synthase kinase activity.

Jackie Vandenheede;Shiaw-Der Yang;Jozef Goris;Wilfried Merlevede.
Journal of Biological Chemistry (1980)

256 Citations

ATP x Mg-dependent protein phosphatase from rabbit skeletal muscle. I. Purification of the enzyme and its regulation by the interaction with an activating protein factor.

Shiaw-Der Yang;Jackie Vandenheede;Jozef Goris;Wilfried Merlevede.
Journal of Biological Chemistry (1980)

250 Citations

Okadaic acid, a specific protein phosphatase inhibitor, induces maturation and MPF formation in Xenopus laevis oocytes.

Jozef Goris;Jacques Hermann;Peter Hendrix;René Ozon.
FEBS Letters (1989)

221 Citations

p38 mitogen-activated protein kinase regulates a novel, caspase-independent pathway for the mitochondrial cytochrome c release in ultraviolet B radiation-induced apoptosis.

Zerihun Assefa;Annelies Vantieghem;Marjan Garmyn;Wim Declercq.
Journal of Biological Chemistry (2000)

219 Citations

Differential stimulation of ERK and JNK activities by ultraviolet B irradiation and epidermal growth factor in human keratinocytes

Zerihun Assefa;Maryan Garmyn;Roger Bouillon;Wilfried Merlevede.
Journal of Investigative Dermatology (1997)

206 Citations

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