Wilfried Merlevede

Overview

Best Publications

• Hypericin in cancer treatment: more light on the way.

  Patrizia Agostinis;Annelies Vantieghem;Wilfried Merlevede;Peter A.M. de Witte

  597
  Citations

• alpha- and beta-forms of the 65-kDa subunit of protein phosphatase 2A have a similar 39 amino acid repeating structure.

  Hemmings Ba;Adams-Pearson C;Maurer F;Müller P

  345
  Citations

• The activation of the c-Jun N-terminal kinase and p38 mitogen-activated protein kinase signaling pathways protects HeLa cells from apoptosis following photodynamic therapy with hypericin.

  Zerihun Assefa;Annelies Vantieghem;Wim Declercq;Peter Vandenabeele

  305
  Citations

• Structure of the 55-kDa regulatory subunit of protein phosphatase 2A: evidence for a neuronal-specific isoform

  Regina E. Mayer;Peter Hendrix;Peter Cron;Renate Matthies

  277
  Citations

• ATP x Mg-dependent protein phosphatase from rabbit skeletal muscle. II. Purification of the activating factor and its characterization as a bifunctional protein also displaying synthase kinase activity.

  Jackie Vandenheede;Shiaw-Der Yang;Jozef Goris;Wilfried Merlevede

  276
  Citations

• The MgATP-Dependent Protein Phosphatase and Protein Phosphatase 1 Have Identical Substrate Specificities

  Alexander A. Stewart;Brian A. Hemmings;Philip Cohen;Jozef Goris

  266
  Citations

• ATP x Mg-dependent protein phosphatase from rabbit skeletal muscle. I. Purification of the enzyme and its regulation by the interaction with an activating protein factor.

  Shiaw-Der Yang;Jackie Vandenheede;Jozef Goris;Wilfried Merlevede

  255
  Citations

• Okadaic acid, a specific protein phosphatase inhibitor, induces maturation and MPF formation in Xenopus laevis oocytes.

  Jozef Goris;Jacques Hermann;Peter Hendrix;René Ozon

  228
  Citations

• p38 mitogen-activated protein kinase regulates a novel, caspase-independent pathway for the mitochondrial cytochrome c release in ultraviolet B radiation-induced apoptosis.

  Zerihun Assefa;Annelies Vantieghem;Marjan Garmyn;Wim Declercq

  221
  Citations

• Differential stimulation of ERK and JNK activities by ultraviolet B irradiation and epidermal growth factor in human keratinocytes.

  Zerihun Assefa;Maryan Garmyn;Roger Bouillon;Wilfried Merlevede

  210
  Citations

• Purification of porcine brain protein phosphatase 2A leucine carboxyl methyltransferase and cloning of the human homologue.

  De Baere I;Derua R;Janssens;Van Hoof C

  208
  Citations

• Structure and expression of a 72-kDa regulatory subunit of protein phosphatase 2A. Evidence for different size forms produced by alternative splicing.

  Peter Hendrix;R E Mayer-Jackel;P Cron;Jozef Goris

  205
  Citations

• Dephosphorylation of tau protein and Alzheimer paired helical filaments by calcineurin and phosphatase-2A

  G Drewes;E M Mandelkow;K Baumann;Jozef Goris

  202
  Citations

• Hypericin-induced photosensitization of HeLa cells leads to apoptosis or necrosis Involvement of cytochrome c and procaspase-3 activation in the mechanism of apoptosis

  Annelies Vantieghem;Zerihun Assefa;Peter Vandenabeele;Wim Declercq

  191
  Citations

• Phosphorylation of Bcl-2 in G2/M phase-arrested cells following photodynamic therapy with hypericin involves a CDK1-mediated signal and delays the onset of apoptosis

  Annelies Vantieghem;Yan Xu;Zerihun Assefa;Jacques Piette

  164
  Citations

• Vascular endothelial growth factor measured in platelet poor plasma allows optimal separation between cancer patients and volunteers: A key to study an angiogenic marker in vivo?

  Wim Wynendaele;Rita Derua;Marc Hoylaerts;A Pawinski

  152
  Citations

• A simplified procedure for the purification of the protein phosphatase modulator (inhibitor-2) from rabbit skeletal muscle

  Shiaw-Der Yang;Jackie R. Vandenheede;Wilfried Merlevede

  151
  Citations

• Initial reactions in the metabolism of D- and L-glyceraldehyde by rat liver.

  Bernard R. Landau;Wilfried Merlevede;Hollis R. Williams

  146
  Citations

• Fluorescence detection of flat bladder carcinoma in situ after intravesical instillation of hypericin.

  Marie-Ange D’Hallewin;Peter A. De Witte;Etienne Waelkens;Wilfried Merlevede

  142
  Citations

• On the mechanism of activation of the ATP X Mg(II)-dependent phosphoprotein phosphatase by kinase FA.

  S Jurgensen;E Shacter;C Y Huang;P B Chock

  140
  Citations