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Lorenzo A. Pinna

Lorenzo A. Pinna

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Biology and Biochemistry
Italy
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
93
Citations
30058
World Ranking
2115
National Ranking
34

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Italy Leader Award

Overview

Lorenzo A. Pinna is affiliated with the University of Padua in Italy and has contributed extensively to the fields of biochemistry, genetics, and molecular biology. Their body of work demonstrates particular engagement with molecular biology, cell biology, materials chemistry, genetics, and spectroscopy.

Their research interests cover a range of topics including:

  • Protein Kinase Regulation and GTPase Signaling
  • Cell death mechanisms and regulation
  • Wnt/β-catenin signaling in development and cancer
  • Advanced Proteomics Techniques and Applications
  • Peptidase Inhibition and Analysis
  • Hippo pathway signaling and YAP/TAZ
  • Autophagy in Disease and Therapy

Among Lorenzo A. Pinna's recent publications are:

  • "Targeting CK2 in cancer: a valuable strategy or a waste of time?" (2021), published in Cell Death Discovery
  • "How can a traffic light properly work if it is always green? The paradox of CK2 signaling" (2021), published in Critical Reviews in Biochemistry and Molecular Biology
  • "Phosphorylation of FAM134C by CK2 controls starvation-induced ER-phagy" (2022), published in Science Advances
  • ""Janus" efficacy of CX-5011: CK2 inhibition and methuosis induction by independent mechanisms" (2020), published in Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  • "Prevalence and significance of the commonest phosphorylated motifs in the human proteome: a global analysis" (2020), published in Cellular and Molecular Life Sciences

Lorenzo A. Pinna cooperates frequently with a number of co-authors, including:

  • Mauro Salvi
  • Christian Borgo
  • Maria Ruzzene
  • Claudio D'Amore
  • Luca Cesaro

The primary venues for their publications include:

  • Cell Death Discovery
  • Critical Reviews in Biochemistry and Molecular Biology
  • Science Advances
  • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  • European Journal of Medicinal Chemistry

In addition to articles, Lorenzo A. Pinna has contributed to academic book literature. One such work is Casein kinases in human diseases, published by Frontiers Media in 2023.

Best Publications

  • One-thousand-and-one substrates of protein kinase CK2?

    Flavio Meggio;Lorenzo A. Pinna

  • Casein kinase 2: an 'eminence grise' in cellular regulation?

    Lorenzo A. Pinna

  • How do protein kinases recognize their substrates

    Lorenzo A Pinna;Maria Ruzzene

  • Protein kinase CK2: a challenge to canons.

    Lorenzo A. Pinna

  • Selectivity of 4,5,6,7-tetrabromobenzotriazole, an ATP site-directed inhibitor of protein kinase CK2 ('casein kinase-2').

    Stefania Sarno;Helen Reddy;Flavio Meggio;Maria Ruzzene

  • Protein kinase CK2 ("casein kinase-2") and its implication in cell division and proliferation.

    Lorenzo A. Pinna;Flavio Meggio

  • Roscovitine Targets, Protein Kinases and Pyridoxal Kinase

    Stéphane Bach;Marie Knockaert;Jens Reinhardt;Olivier Lozach

  • Addiction to protein kinase CK2: a common denominator of diverse cancer cells?

    Maria Ruzzene;Lorenzo A. Pinna

  • Protein kinase CK2 phosphorylates and upregulates Akt/PKB.

    G Di Maira;M Salvi;G Arrigoni;O Marin

  • The Protein Kinase CK2 Facilitates Repair of Chromosomal DNA Single-Strand Breaks

    Joanna I. Loizou;Sherif F. El-Khamisy;Anastasia Zlatanou;David J. Moore

  • Different susceptibility of protein kinases to staurosporine inhibition Kinetic studies and molecular bases for the resistance of protein kinase CK2

    Flavio Meggio;Arianna Donella Deana;Maria Ruzzene;Anna M. Brunati

  • Chronic lymphocytic leukemia B cells contain anomalous Lyn tyrosine kinase, a putative contribution to defective apoptosis

    Antonella Contri;Anna Maria Brunati;Livio Trentin;Anna Cabrelle

  • A Single Kinase Generates the Majority of the Secreted Phosphoproteome

    Vincent S. Tagliabracci;Sandra E. Wiley;Xiao Guo;Lisa N. Kinch

  • Protein kinase CK2 inhibitor 4,5,6,7-tetrabromobenzotriazole (TBB) induces apoptosis and caspase-dependent degradation of haematopoietic lineage cell-specific protein 1 (HS1) in Jurkat cells

    Maria Ruzzene;Daniele Penzo;Lorenzo A Pinna

  • The selectivity of inhibitors of protein kinase CK2: an update.

    Mario A Pagano;Jenny Bain;Zygmunt Kazimierczuk;Stefania Sarno

  • Bcr-Abl stabilizes β-catenin in chronic myeloid leukemia through its tyrosine phosphorylation

    Addolorata Maria Luce Coluccia;Addolorata Maria Luce Coluccia;Angelo Vacca;Mireia Duñach;Luca Mologni

  • Substrate specificity of protein kinase CK2.

    Flavio Meggio;Oriano Marin;Lorenzo Pinna

  • Crystal structure of the catalytic subunit of protein kinase CK2 from Zea mays at 2.1 A resolution

    Karsten Niefind;Barbara Guerra;Lorenzo A. Pinna;Olaf‐Georg Issinger

  • Site specificity of casein kinase-2 (TS) from rat liver cytosol. A study with model peptide substrates.

    Oriano Marin;Flavio Meggio;Fernando Marchiori;Gianfranco Borin

  • Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole.

    Mario A Pagano;Mariola Andrzejewska;Maria Ruzzene;Stefania Sarno

Frequent Co-Authors

Flavio Meggio
Flavio Meggio University of Padua
Oriano Marin
Oriano Marin University of Padua
Stefania Sarno
Stefania Sarno University of Bologna
Maria Ruzzene
Maria Ruzzene University of Padua
Anna Maria Brunati
Anna Maria Brunati University of Padua
Stefano Moro
Stefano Moro University of Padua
Giuseppe Zanotti
Giuseppe Zanotti University of Padua
Peter James
Peter James Lund University

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