David Shugar

Overview

Best Publications

• The measurement of lysozyme activity and the ultra-violet inactivation of lysozyme.

  Unknown

  1113
  Citations

• Comparative Efficacy of Antiherpes Drugs against Different Strains of Herpes Simplex Virus

  E. De Clercq;J. Descamps;G. Verhelst;R. T. Walker

  869
  Citations

• Purine nucleoside phosphorylases: properties, functions, and clinical aspects.

  Agnieszka Bzowska;Ewa Kulikowska;David Shugar;David Shugar

  705
  Citations

• Selectivity of 4,5,6,7-tetrabromobenzotriazole, an ATP site-directed inhibitor of protein kinase CK2 ('casein kinase-2').

  Stefania Sarno;Helen Reddy;Flavio Meggio;Maria Ruzzene

  437
  Citations

• Spectrophotometric studies of nucleic acid derivatives and related compounds as a function of pH. I. Pyrimidines.

  Unknown

  353
  Citations

• MATRIX ISOLATION STUDIES OF NUCLEIC ACID CONSTITUENTS. I. INFRARED SPECTRA OF URACIL MONOMERS

  M. Szczesniak;M. J. Nowak;H. Rostkowska;Krystyna Szczepaniak

  260
  Citations

• Molecular mechanism of human Nrf2 activation and degradation: role of sequential phosphorylation by protein kinase CK2.

  Jingbo Pi;Yushi Bai;Jeffrey M. Reece;Jason Williams

  257
  Citations

• UV–Vis spectroscopy of tyrosine side-groups in studies of protein structure. Part 2: selected applications

  Jan M. Antosiewicz;David Shugar

  255
  Citations

• Ribofuranosyl‐benzimidazole derivatives as inhibitors of casein kinase‐2 and casein kinase‐1

  Flavio Meggio;David Shugar;Lorenzo A. Pinna

  179
  Citations

• Conformation of the exocyclic 5′-CH2OH in nucleosides and nucleotides in aqueous solution from specific assignments of the H5′, and H5″ signals in the NMR spectra

  M. Remin;M. Remin;D. Shugar;D. Shugar

  179
  Citations

• Halogenated benzimidazoles and benzotriazoles as selective inhibitors of protein kinases CK I and CK II from Saccharomyces cerevisiae and other sources.

  Ryszard Szyszka;Nikodem Grankowski;Krzysztof Felczak;David Shugar

  179
  Citations

• Carbon Monoxide Neurotransmission Activated by CK2 Phosphorylation of Heme Oxygenase-2

  Darren F. Boehning;Cheil Moon;Sumit Sharma;K. Joseph Hurt

  174
  Citations

• Mammalian nucleolytic enzymes.

  Halina Sierakowska;David Shugar

  165
  Citations

• Halogenated benzimidazoles and benzotriazoles as inhibitors of the NTPase/helicase activities of hepatitis C and related viruses.

  Peter Borowski;Johanna Deinert;Sarah Schalinski;Maria Bretner

  164
  Citations

• 5-substituted 2′-deoxyuridines: Correlation between inhibition of tumor cell growth and inhibition of thymidine kinase and thymidylate synthetase

  Jan Balzarini;Erik De Clercq;Mathias P. Mertes;David Shugar

  134
  Citations

• Xanthine, xanthosine and its nucleotides: solution structures of neutral and ionic forms, and relevance to substrate properties in various enzyme systems and metabolic pathways

  Ewa Kulikowska;Borys Kierdaszuk;David Shugar

  133
  Citations

• Tetrabromobenzotriazole (TBBt) and tetrabromobenzimidazole (TBBz) as selective inhibitors of protein kinase CK2: evaluation of their effects on cells and different molecular forms of human CK2.

  Piotr Zien;James S. Duncan;Janusz Skierski;Maria Bretner

  125
  Citations

• Tautomerism of Isoguanosine and Solvent-Induced Keto-Enol Equilibrium

  Jerzy Sepioł;Zygmunt Kazimierczuk;David Shugar

  123
  Citations

• The ultraviolet absorption spectrum of ribonuclease.

  Unknown

  122
  Citations

• Properties of two unusual, and fluorescent, substrates of purine-nucleoside phosphorylase: 7-methylguanosine and 7-methylinosine.

  Ewa Kulikowska;Agnieszka Bzowska;Jacek Wierzchowski;David Shugar

  120
  Citations

• Activation of rat liver AMP-activated protein kinase by kinase kinase in a purified, reconstituted system. Effects of AMP and AMP analogues.

  J Weekes;S A Hawley;J Corton;D Shugar

  120
  Citations

• Crystal structure of the ternary complex of E. coli purine nucleoside phosphorylase with formycin B, a structural analogue of the substrate inosine, and phosphate (Sulphate) at 2.1 A resolution.

  Gertraud Koellner;Marija Luić;David Shugar;Wolfram Saenger

  116
  Citations

• Crystal structure of calf spleen purine nucleoside phosphorylase in a complex with hypoxanthine at 2.15 A resolution.

  Gertraud Koellner;Marija Luić;David Shugar;Wolfram Saenger

  108
  Citations

• Biochemistry and biology of DNA methylation

  David Shugar

  93
  Citations