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Biology and Biochemistry

D-Index
60
Citations
9952
World Ranking
12194
National Ranking
55

Overview

Walter Filgueira de Azevedo is affiliated with the Pontifical Catholic University of Rio Grande do Sul in Brazil. Their research spans multiple fields of study, primarily within Computer Science and Biochemistry, Genetics and Molecular Biology, contributing to a total of 75 publications across these domains.

Their work encompasses several subfields, including Molecular Biology, Computational Theory and Mathematics, Oncology, Materials Chemistry, and Mechanical Engineering. The main research topics focus on Computational Drug Discovery Methods, Protein Structure and Dynamics, Bioinformatics and Genomic Networks, Enzyme Structure and Function, Cancer-related Molecular Pathways, Microtubule and Mitosis Dynamics, as well as Modular Robots and Swarm Intelligence.

Frequent publication venues for their work include:

  • Methods in Molecular Biology
  • Current Medicinal Chemistry
  • Frontiers in Chemistry
  • Journal of Computational Chemistry
  • Exploration of Drug Science

Frequent co-authors in their research are:

  • Amauri Duarte da Silva
  • Gabriela Bitencourt-Ferreira
  • Nelson José Freitas da Silveira
  • Martina Veit-Acosta
  • Olga Tarasova

Some recent publications authored or co-authored by Walter Filgueira de Azevedo include:

  • Application of Machine Learning Techniques for Drug Discovery, 2021, Current Medicinal Chemistry
  • Electrostatic Potential Energy in Protein-Drug Complexes, 2021, Current Medicinal Chemistry
  • Computational Prediction of Binding Affinity for CDK2-ligand Complexes.A Protein Target for Cancer Drug Discovery, 2021, Current Medicinal Chemistry
  • Interaction of Copper Potential Metallodrugs with TMPRSS2: A Comparative Study of Docking Tools and Its Implications on COVID-19, 2023, Frontiers in Chemistry
  • Exploring Scoring Function Space: Developing Computational Models for Drug Discovery, 2023, Current Medicinal Chemistry

The research by Walter Filgueira de Azevedo reflects interdisciplinary integration, combining computational methods with molecular biology to address challenges within drug discovery and molecular interactions. Their contributions include the study of enzyme dynamics, cancer molecular pathways, and the development of computational models relevant to pharmacological applications.

Best Publications

  • Inhibition of Cyclin‐Dependent Kinases by Purine Analogues

    Walter Filgueira De Azevedo;Sophie Leclerc;Laurent Meijer;Libor Havlicek

  • Halogen atoms in the modern medicinal chemistry: hints for the drug design.

    Marcelo Zaldini Hernandes;Suellen Melo T. Cavalcanti;Diogo Rodrigo M. Moreira;Walter Filgueira de Azevedo Junior

  • Molecular docking algorithms.

    Raquel Dias;Walter Filgueira de Azevedo

  • 4-Arylazo-3,5-diamino-1H-pyrazole CDK Inhibitors: SAR Study, Crystal Structure in Complex with CDK2, Selectivity, and Cellular Effects†

    Vladimir Krystof;Petr Cankar;Iveta Frysova;Jan Slouka

  • Anoplin, a novel antimicrobial peptide from the venom of the solitary wasp Anoplius samariensis.

    Katsuhiro Konno;Miki Hisada;Renato Fontana;Carla C.B. Lorenzi

  • Molegro Virtual Docker for Docking

    Gabriela Bitencourt-Ferreira;Walter Filgueira de Azevedo

  • Structural basis for inhibition of cyclin-dependent kinase 9 by flavopiridol.

    Walter Filgueira de Azevedo;Fernanda Canduri;Fernanda Canduri;Nelson José Freitas da Silveira

  • The use of biodiversity as source of new chemical entities against defined molecular targets for treatment of malaria, tuberculosis, and T-cell mediated diseases: a review

    Luiz Augusto Basso;Luiz Hildebrando Pereira da Silva;Arthur Germano Fett-Neto;Walter Filgueira de Azevedo Junior

  • MolDock applied to structure-based virtual screening.

    Walter Filgueira De Azevedo

  • How C-terminal carboxyamidation alters the biological activity of peptides from the venom of the eumenine solitary wasp.

    Mauricio L. Sforca;Sérgio Oyama;Fernanda Canduri;Carla C. B. Lorenzi

  • Automated NMR structure determination and disulfide bond identification of the myotoxin crotamine from Crotalus durissus terrificus

    Valmir Fadel;Pascal Bettendorff;Torsten Herrmann;Walter F. de Azevedo

  • Antimalarial Activity of Physalins B, D, F, and G

    Matheus S. Sá;Maria N. de Menezes;Antoniana U. Krettli;Ivone M. Ribeiro

  • SAnDReS a Computational Tool for Statistical Analysis of Docking Results and Development of Scoring Functions

    Mariana Morrone Xavier;Gabriela Sehnem Heck;Mauricio Boff de Avila;Nayara Maria Bernhardt Levin

  • Supervised Machine Learning Methods Applied to Predict Ligand- Binding Affinity.

    Gabriela Sehnem Heck;Val Oliveira Pintro;Richard Rene Pereira;Mauricio Boff de Ávila

  • Crystallographic and Pre-steady-state Kinetics Studies on Binding of NADH to Wild-type and Isoniazid-resistant Enoyl-ACP(CoA) Reductase Enzymes from Mycobacterium tuberculosis

    Jaim S. Oliveira;José H. Pereira;Fernanda Canduri;Nathália C. Rodrigues

  • Molecular model of cyclin-dependent kinase 5 complexed with roscovitine

    Walter Filgueira de Azevedo;Walter Filgueira de Azevedo;Renato Tadeu Gaspar;Fernanda Canduri;Fernanda Canduri;João Carlos Camera

  • Structure of a lectin from Canavalia gladiata seeds: new structural insights for old molecules

    Plinio Delatorre;Bruno A. M. Rocha;Emmanuel P. Souza;Taiana M. Oliveira

  • Structure of shikimate kinase from Mycobacterium tuberculosis reveals the binding of shikimic acid.

    José Henrique Pereira;Jaim Simões De Oliveira;Fernanda Canduri;Marcio Vinicius Bertacine Dias

  • CDK9 a potential target for drug development.

    Fernanda Canduri;Patricia Cardoso Peres;Rafael Andrade Caceres;Walter Filgueira de Azevedo

  • Parmodel: a web server for automated comparative modeling of proteins.

    Hugo Brandão Uchôa;Guilherme Eberhart Jorge;Nelson José Freitas Da Silveira;João Carlos Camera

Frequent Co-Authors

Benildo Sousa Cavada
Benildo Sousa Cavada Universidade Federal do Ceará
Milena Botelho Pereira Soares
Milena Botelho Pereira Soares Oswaldo Cruz Foundation
Sung-Hou Kim
Sung-Hou Kim University of California, Berkeley
Richard J. Ward
Richard J. Ward Universidade de São Paulo
Juan J. Calvete
Juan J. Calvete Spanish National Research Council
Miroslav Strnad
Miroslav Strnad Palacký University, Olomouc
José R. Giglio
José R. Giglio Universidade de São Paulo
Tao Huang
Tao Huang Chinese Academy of Sciences
Yu-Dong Cai
Yu-Dong Cai Shanghai University
Yoshihiro Nakata
Yoshihiro Nakata Hiroshima University

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