Her primary scientific interests are in Biochemistry, Kinase, Protein kinase A, Casein kinase 2 and Molecular biology. Her Kinase study integrates concerns from other disciplines, such as GTP', Signal transduction, Stereochemistry and In vivo. Her studies in Protein kinase A integrate themes in fields like Cell culture, Cancer research, Gene silencing and Biological activity.
Her Casein kinase 2 research is multidisciplinary, relying on both Caspase, Arabidopsis thaliana and Nitrate reductase. Her Casein kinase 1 study incorporates themes from Protein phosphorylation, Apoptosis, Phosphorylase kinase and GSK-3. Her study in the field of Phosphatase is also linked to topics like Calcineurin.
Biochemistry, Phosphorylation, Kinase, Protein kinase A and Casein kinase 2 are her primary areas of study. Her study on Biochemistry is mostly dedicated to connecting different topics, such as Molecular biology. Her work deals with themes such as Tyrosine kinase and Peptide, which intersect with Phosphorylation.
Her Kinase research includes elements of In vitro, Cancer cell, Apoptosis, Signal transduction and Stereochemistry. Her Protein kinase A research is multidisciplinary, incorporating perspectives in Phenotype, Gene, Mitogen-activated protein kinase and Drug resistance. Her work carried out in the field of Casein kinase 2 brings together such families of science as Casein kinase 2, alpha 1, Cell growth, Protein subunit, MAP2K7 and In vivo.
Maria Ruzzene focuses on Cell biology, Phosphorylation, Signal transduction, Protein kinase A and Kinase. Her Cell biology research includes themes of Cancer cell and Gene isoform. Her study on AKT1, Protein phosphorylation and Protein kinase CK2 activity is often connected to Traffic signal as part of broader study in Phosphorylation.
Her work on Casein kinase 2 as part of general Protein kinase A study is frequently connected to Neurodegeneration, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them. The various areas that Maria Ruzzene examines in her Casein kinase 2 study include Protein kinase CK2, Cancer research, Cell growth and Kinome. The study incorporates disciplines such as Cell culture, Protein subunit and Stereochemistry in addition to Kinase.
Her primary scientific interests are in Protein kinase B, Signal transduction, PI3K/AKT/mTOR pathway, Cell biology and Protein kinase A. She interconnects Immune system, Glioma, Temozolomide, Pharmacology and In vivo in the investigation of issues within Protein kinase B. The concepts of her PI3K/AKT/mTOR pathway study are interwoven with issues in Cancer cell, Hedgehog signaling pathway, Drug resistance, Cell fate determination and Effector.
Her study in Kinase and Phosphorylation falls within the category of Cell biology. Casein kinase 2 is the focus of her Protein kinase A research. Throughout her Casein kinase 2 studies, Maria Ruzzene incorporates elements of other sciences such as Chronic leukemia and Pleiotropy.
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How do protein kinases recognize their substrates
Lorenzo A Pinna;Maria Ruzzene.
Biochimica et Biophysica Acta (1996)
Selectivity of 4,5,6,7-tetrabromobenzotriazole, an ATP site-directed inhibitor of protein kinase CK2 ('casein kinase-2').
Stefania Sarno;Helen Reddy;Flavio Meggio;Maria Ruzzene.
FEBS Letters (2001)
Addiction to protein kinase CK2: a common denominator of diverse cancer cells?
Maria Ruzzene;Lorenzo A. Pinna.
Biochimica et Biophysica Acta (2010)
Protein kinase CK2 phosphorylates and upregulates Akt/PKB.
G Di Maira;M Salvi;G Arrigoni;O Marin.
Cell Death & Differentiation (2005)
Different susceptibility of protein kinases to staurosporine inhibition Kinetic studies and molecular bases for the resistance of protein kinase CK2
Flavio Meggio;Arianna Donella Deana;Maria Ruzzene;Anna M. Brunati.
FEBS Journal (1995)
Protein kinase CK2 inhibitor 4,5,6,7-tetrabromobenzotriazole (TBB) induces apoptosis and caspase-dependent degradation of haematopoietic lineage cell-specific protein 1 (HS1) in Jurkat cells
Maria Ruzzene;Daniele Penzo;Lorenzo A Pinna.
Biochemical Journal (2002)
The selectivity of inhibitors of protein kinase CK2: an update.
Mario A Pagano;Jenny Bain;Zygmunt Kazimierczuk;Stefania Sarno.
Biochemical Journal (2008)
Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole.
Mario A Pagano;Mariola Andrzejewska;Maria Ruzzene;Stefania Sarno.
Journal of Medicinal Chemistry (2004)
Salicylic acid activates nitric oxide synthesis in Arabidopsis
Michela Zottini;Alex Costa;Roberto De Michele;Maria Ruzzene.
Journal of Experimental Botany (2007)
2-dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole: a novel powerful and selective inhibitor of protein kinase CK2
Mario A. Pagano;Flavio Meggio;Maria Ruzzene;Mariola Andrzejewska.
Biochemical and Biophysical Research Communications (2004)
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