What is she best known for?
The fields of study she is best known for:
Her primary scientific interests are in Biochemistry, Kinase, Protein kinase A, Casein kinase 2 and Molecular biology.
Her Kinase study integrates concerns from other disciplines, such as GTP', Signal transduction, Stereochemistry and In vivo.
Her studies in Protein kinase A integrate themes in fields like Cell culture, Cancer research, Gene silencing and Biological activity.
Her Casein kinase 2 research is multidisciplinary, relying on both Caspase, Arabidopsis thaliana and Nitrate reductase.
Her Casein kinase 1 study incorporates themes from Protein phosphorylation, Apoptosis, Phosphorylase kinase and GSK-3.
Her study in the field of Phosphatase is also linked to topics like Calcineurin.
Her most cited work include:
- How do protein kinases recognize their substrates (401 citations)
- Selectivity of 4,5,6,7-tetrabromobenzotriazole, an ATP site-directed inhibitor of protein kinase CK2 ('casein kinase-2'). (315 citations)
- Addiction to protein kinase CK2: a common denominator of diverse cancer cells? (255 citations)
What are the main themes of her work throughout her whole career to date?
Biochemistry, Phosphorylation, Kinase, Protein kinase A and Casein kinase 2 are her primary areas of study.
Her study on Biochemistry is mostly dedicated to connecting different topics, such as Molecular biology.
Her work deals with themes such as Tyrosine kinase and Peptide, which intersect with Phosphorylation.
Her Kinase research includes elements of In vitro, Cancer cell, Apoptosis, Signal transduction and Stereochemistry.
Her Protein kinase A research is multidisciplinary, incorporating perspectives in Phenotype, Gene, Mitogen-activated protein kinase and Drug resistance.
Her work carried out in the field of Casein kinase 2 brings together such families of science as Casein kinase 2, alpha 1, Cell growth, Protein subunit, MAP2K7 and In vivo.
She most often published in these fields:
- Biochemistry (51.67%)
- Phosphorylation (38.33%)
- Kinase (33.33%)
What were the highlights of her more recent work (between 2016-2021)?
- Cell biology (23.33%)
- Phosphorylation (38.33%)
- Signal transduction (18.33%)
In recent papers she was focusing on the following fields of study:
Maria Ruzzene focuses on Cell biology, Phosphorylation, Signal transduction, Protein kinase A and Kinase.
Her Cell biology research includes themes of Cancer cell and Gene isoform.
Her study on AKT1, Protein phosphorylation and Protein kinase CK2 activity is often connected to Traffic signal as part of broader study in Phosphorylation.
Her work on Casein kinase 2 as part of general Protein kinase A study is frequently connected to Neurodegeneration, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them.
The various areas that Maria Ruzzene examines in her Casein kinase 2 study include Protein kinase CK2, Cancer research, Cell growth and Kinome.
The study incorporates disciplines such as Cell culture, Protein subunit and Stereochemistry in addition to Kinase.
Between 2016 and 2021, her most popular works were:
- Therapeutic targeting of CK2 in acute and chronic leukemias (52 citations)
- Cross-talk between the CK2 and AKT signaling pathways in cancer. (28 citations)
- Role of protein kinase CK2 in antitumor drug resistance (22 citations)
In her most recent research, the most cited papers focused on:
Her primary scientific interests are in Protein kinase B, Signal transduction, PI3K/AKT/mTOR pathway, Cell biology and Protein kinase A.
She interconnects Immune system, Glioma, Temozolomide, Pharmacology and In vivo in the investigation of issues within Protein kinase B.
The concepts of her PI3K/AKT/mTOR pathway study are interwoven with issues in Cancer cell, Hedgehog signaling pathway, Drug resistance, Cell fate determination and Effector.
Her study in Kinase and Phosphorylation falls within the category of Cell biology.
Casein kinase 2 is the focus of her Protein kinase A research.
Throughout her Casein kinase 2 studies, Maria Ruzzene incorporates elements of other sciences such as Chronic leukemia and Pleiotropy.
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