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Maria Ruzzene

Maria Ruzzene

D-Index & Metrics

Biology and Biochemistry

D-Index
46
Citations
8917
World Ranking
18899
National Ranking
604

Overview

Maria Ruzzene is affiliated with the University of Padua in Italy and conducts research primarily in the fields of Biochemistry, Genetics, and Molecular Biology, with additional work in Medicine. Their research interests span several subfields including Molecular Biology, Genetics, Materials Chemistry, Hematology, and Immunology.

Their work heavily focuses on topics related to Protein Kinase Regulation and GTPase Signaling, Cell Death Mechanisms and Regulation, Phagocytosis and Immune Regulation, PI3K/AKT/mTOR Signaling in Cancer, Chronic Myeloid Leukemia Treatments, Chronic Lymphocytic Leukemia Research, and Peptidase Inhibition and Analysis.

Ruzzene has coauthored multiple publications with several researchers, including:

  • Christian Borgo (8 collaborations)
  • Mauro Salvi (7 collaborations)
  • Lorenzo A. Pinna (5 collaborations)
  • Stefania Sarno (4 collaborations)
  • Camila Paz Quezada Meza (4 collaborations)

Their research is published in a variety of scientific venues, with multiple articles appearing in "Kinases and Phosphatases." Other frequent publication venues include:

  • Signal Transduction and Targeted Therapy
  • Cell Death Discovery
  • Advances in Protein Chemistry and Structural Biology
  • Critical Reviews in Biochemistry and Molecular Biology

Recent papers by Ruzzene include:

  • "Protein kinase CK2: a potential therapeutic target for diverse human diseases," 2021, Signal Transduction and Targeted Therapy
  • "Targeting CK2 in cancer: a valuable strategy or a waste of time?", 2021, Cell Death Discovery
  • "Protein kinase CK2 inhibition as a pharmacological strategy," 2021, Advances in Protein Chemistry and Structural Biology
  • "How can a traffic light properly work if it is always green? The paradox of CK2 signaling," 2021, Critical Reviews in Biochemistry and Molecular Biology
  • "Phosphorylation of FAM134C by CK2 controls starvation-induced ER-phagy," 2022, Science Advances

Best Publications

  • How do protein kinases recognize their substrates

    Lorenzo A Pinna;Maria Ruzzene

  • Selectivity of 4,5,6,7-tetrabromobenzotriazole, an ATP site-directed inhibitor of protein kinase CK2 ('casein kinase-2').

    Stefania Sarno;Helen Reddy;Flavio Meggio;Maria Ruzzene

  • Addiction to protein kinase CK2: a common denominator of diverse cancer cells?

    Maria Ruzzene;Lorenzo A. Pinna

  • Protein kinase CK2 phosphorylates and upregulates Akt/PKB.

    G Di Maira;M Salvi;G Arrigoni;O Marin

  • Different susceptibility of protein kinases to staurosporine inhibition Kinetic studies and molecular bases for the resistance of protein kinase CK2

    Flavio Meggio;Arianna Donella Deana;Maria Ruzzene;Anna M. Brunati

  • Protein kinase CK2 inhibitor 4,5,6,7-tetrabromobenzotriazole (TBB) induces apoptosis and caspase-dependent degradation of haematopoietic lineage cell-specific protein 1 (HS1) in Jurkat cells

    Maria Ruzzene;Daniele Penzo;Lorenzo A Pinna

  • The selectivity of inhibitors of protein kinase CK2: an update.

    Mario A Pagano;Jenny Bain;Zygmunt Kazimierczuk;Stefania Sarno

  • Salicylic acid activates nitric oxide synthesis in Arabidopsis

    Michela Zottini;Alex Costa;Roberto De Michele;Maria Ruzzene

  • Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole.

    Mario A Pagano;Mariola Andrzejewska;Maria Ruzzene;Stefania Sarno

  • Protein kinase CK2: a potential therapeutic target for diverse human diseases.

    Christian Borgo;Claudio D'Amore;Stefania Sarno;Mauro Salvi

  • 2-dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole: a novel powerful and selective inhibitor of protein kinase CK2

    Mario A. Pagano;Flavio Meggio;Maria Ruzzene;Mariola Andrzejewska

  • QUINALIZARIN AS A POTENT, SELECTIVE AND CELL PERMEABLE INHIBITOR OF PROTEIN KINASE CK2.

    Giorgio Cozza;Marco Mazzorana;Elena Papinutto;Jenny Bain

  • Biochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5,6-dihydroindolo-(1,2-a)quinazolin-7-yl]acetic acid (IQA).

    Stefania Sarno;Erika De Moliner;Maria Ruzzene;Mario A. Pagano

  • PLG72 Modulates Intracellular D-Serine Levels through Its Interaction with D-Amino Acid Oxidase : EFFECT ON SCHIZOPHRENIA SUSCEPTIBILITY

    Silvia Sacchi;Mariagrazia Bernasconi;Magalie Martineau;Jean-Pierre Mothet

  • Multiple myeloma cell survival relies on high activity of protein kinase CK2

    Francesco A. Piazza;Maria Ruzzene;Carmela Gurrieri;Barbara Montini

  • Tetrabromocinnamic acid (TBCA) and related compounds represent a new class of specific protein kinase CK2 inhibitors.

    Mario A. Pagano;Giorgia Poletto;Giovanni Di Maira;Giorgio Cozza

  • Casein kinase: the triple meaning of a misnomer.

    Andrea Venerando;Maria Ruzzene;Lorenzo A. Pinna

  • Dephosphorylation of phosphopeptides by calcineurin (protein phosphatase 2B)

    Arianna Donella-Deana;Marie H. Krinks;Maria Ruzzene;Claude Klee

  • Protein kinase CK2 in hematologic malignancies: reliance on a pivotal cell survival regulator by oncogenic signaling pathways

    F Piazza;S Manni;M Ruzzene;L A Pinna

  • Inhibition of protein kinase CK2 by condensed polyphenolic derivatives. An in vitro and in vivo study.

    Flavio Meggio;Mario A. Pagano;Stefano Moro;Giuseppe Zagotto

Frequent Co-Authors

Lorenzo A. Pinna
Lorenzo A. Pinna University of Padua
Stefania Sarno
Stefania Sarno University of Bologna
Oriano Marin
Oriano Marin University of Padua
Anna Maria Brunati
Anna Maria Brunati University of Padua
Flavio Meggio
Flavio Meggio University of Padua
Livio Trentin
Livio Trentin University of Padua
Giuseppe Zanotti
Giuseppe Zanotti University of Padua
Michela Zottini
Michela Zottini University of Padua
Stefano Moro
Stefano Moro University of Padua

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