2026 Lucio Cocco: Biology and Biochemistry Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	79	4332	3998	95	90	442	21550

Research.com Recognitions

2023 - Research.com Biology and Biochemistry in Italy Leader Award

Overview

Lucio Cocco is affiliated with the University of Bologna in Italy and has a significant presence in the scientific community, particularly in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans multiple subfields including Molecular Biology, Hematology, Oncology, Genetics, and Cell Biology.

The scientist's research covers a range of topics, notably:

Acute Myeloid Leukemia Research
Nuclear Structure and Function
Cancer-related Molecular Pathways
Epigenetics and DNA Methylation
RNA Research and Splicing
Wnt/β-catenin signaling in development and cancer
Protein Kinase Regulation and GTPase Signaling

Lucio Cocco has published frequently in several scientific venues, with numerous publications in:

Advances in Biological Regulation
Cells
Blood
International Journal of Molecular Sciences
Cellular and Molecular Life Sciences

Notable recent papers include:

"Targeting GSK3 and Associated Signaling Pathways Involved in Cancer," 2020, Cells
"The wide and growing range of lamin B-related diseases: from laminopathies to cancer," 2022, Cellular and Molecular Life Sciences
"Phosphoinositide-Dependent Signaling in Cancer: A Focus on Phospholipase C Isozymes," 2020, International Journal of Molecular Sciences
"Demethylation and Up-Regulation of an Oncogene after Hypomethylating Therapy," 2022, New England Journal of Medicine
"Effects of TP53 Mutations and miRs on Immune Responses in the Tumor Microenvironment Important in Pancreatic Cancer Progression," 2022, Cells

The scientist collaborates with a range of frequent co-authors, including:

Stefano Ratti
Lucia Manzoli
Matilde Y. Follo
James A. McCubrey
Sara Mongiorgi

Best Publications

Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging

Linda S. Steelman;William H. Chappell;Stephen L. Abrams;C. Ruth Kempf

779
Citations
Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Inhibitors: Rationale and Importance to Inhibiting These Pathways in Human Health

William H. Chappell;Linda S. Steelman;Jacquelyn M. Long;Ruth C. Kempf

691
Citations
Multiple roles of phosphoinositide-specific phospholipase C isozymes.

Pann-Ghill Suh;Jae-Il Park;Lucia Manzoli;Lucio Cocco

596
Citations
GSK-3 as potential target for therapeutic intervention in cancer.

James A. McCubrey;Linda S. Steelman;Fred E. Bertrand;Nicole Marie Davis

538
Citations
Nuclear localization and signalling activity of phosphoinositidase Cβ in Swiss 3T3 cells

Alberto M. Martelli;R. Stewart Gilmour;Valeria Bertagnolo;Luca M. Neri

457
Citations
Synthesis of polyphosphoinositides in nuclei of Friend cells. Evidence for polyphosphoinositide metabolism inside the nucleus which changes with cell differentiation

L Cocco;R S Gilmour;A Ognibene;A J Letcher

425
Citations
Phosphoinositide 3-kinase/Akt signaling pathway and its therapeutical implications for human acute myeloid leukemia.

A M Martelli;M Nyåkern;G Tabellini;R Bortul

415
Citations
NK cells and cancer.

Loris Zamai;Cristina Ponti;Prisco Mirandola;Giuliana Gobbi

395
Citations
Mutations and deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mtor cascades which alter therapy response

James A McCubrey;Linda S Steelman;William H Chappell;Stephen L Abrams

368
Citations
Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascade Inhibitors: How Mutations Can Result in Therapy Resistance and How to Overcome Resistance

James Andrew McCubrey;Linda S. Steelman;William H. Chappell;Stephen L. Abrams

354
Citations
Deregulation of the EGFR/PI3K/PTEN/Akt/mTORC1 pathway in breast cancer: possibilities for therapeutic intervention

Nicole Marie Davis;Melissa Sokolosky;Kristin Stadelman;Stephen L. Abrams

311
Citations
Multifaceted roles of GSK-3 and Wnt/β-catenin in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention

James A. McCubrey;L. S. Steelman;Fred E. Bertrand;Nicole Marie Davis

265
Citations
Multidrug resistance-associated protein 1 expression is under the control of the phosphoinositide 3 kinase/Akt signal transduction network in human acute myelogenous leukemia blasts

P. L. Tazzari;Alessandra Cappellini;F. Ricci;Camilla Evangelisti

253
Citations
Activated human NK and CD8+ T cells express both TNF-related apoptosis-inducing ligand (TRAIL) and TRAIL receptors but are resistant to TRAIL-mediated cytotoxicity

Prisco Mirandola;Cristina Ponti;Giuliana Gobbi;Ivonne Sponzilli

234
Citations
The emerging multiple roles of nuclear Akt

Alberto M. Martelli;Alberto M. Martelli;Giovanna Tabellini;Daniela Bressanin;Andrea Ognibene

227
Citations
Effects of resveratrol, curcumin, berberine and other nutraceuticals on aging, cancer development, cancer stem cells and microRNAs

James A. McCubrey;Kvin Lertpiriyapong;Linda S. Steelman;Steve L. Abrams

218
Citations
Targeting GSK3 and Associated Signaling Pathways Involved in Cancer

Przemysław Duda;Shaw M. Akula;Stephen L. Abrams;Linda S. Steelman

212
Citations
A new selective AKT pharmacological inhibitor reduces resistance to chemotherapeutic drugs, TRAIL, all-trans-retinoic acid, and ionizing radiation of human leukemia cells.

A M Martelli;P L Tazzari;G Tabellini;R Bortul

210
Citations
Therapeutic resistance resulting from mutations in Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR signaling pathways.

James A. McCubrey;Linda S. Steelman;C. Ruth Kempf;William H. Chappell

209
Citations
A Role for Nuclear Phospholipase Cβ1 in Cell Cycle Control

Irene Faenza;Alessandro Matteucci;Lucia Manzoli;Anna Maria Billi

191
Citations