What is he best known for?
The fields of study he is best known for:
Silvano Capitani focuses on Molecular biology, Cell biology, Protein kinase B, PI3K/AKT/mTOR pathway and Apoptosis.
His work deals with themes such as Cell culture, Megakaryocyte, Haematopoiesis, T cell and CD34, which intersect with Molecular biology.
His research combines Biochemistry and Cell biology.
His PI3K/AKT/mTOR pathway research is multidisciplinary, relying on both Cancer research and Cell growth.
Silvano Capitani has researched Cancer research in several fields, including Leukemia and Internal medicine.
The concepts of his Apoptosis study are interwoven with issues in Jurkat cells, Antibody, Transfection and Virology.
His most cited work include:
- The nuclear phosphoinositide 3-kinase/AKT pathway: a new second messenger system (166 citations)
- In Vitro Senescence and Apoptotic Cell Death of Human Megakaryocytes (129 citations)
- Human immunodeficiency virus type 1 Tat protein protects lymphoid, epithelial, and neuronal cell lines from death by apoptosis. (123 citations)
What are the main themes of his work throughout his whole career to date?
Silvano Capitani mostly deals with Molecular biology, Cell biology, Cancer research, Biochemistry and Protein kinase B.
His studies deal with areas such as Cell culture, Nuclear matrix, Apoptosis, T cell and Gene isoform as well as Molecular biology.
Silvano Capitani has included themes like Jurkat cells and Transfection in his Apoptosis study.
His Cellular differentiation research extends to the thematically linked field of Cell biology.
His Cancer research study combines topics in areas such as Haematopoiesis, Immunology, Internal medicine, Metastasis and Breast cancer.
Silvano Capitani focuses mostly in the field of Protein kinase B, narrowing it down to topics relating to PI3K/AKT/mTOR pathway and, in certain cases, Pharmacology, Cell growth and Cell cycle checkpoint.
He most often published in these fields:
- Molecular biology (26.16%)
- Cell biology (26.16%)
- Cancer research (21.94%)
What were the highlights of his more recent work (between 2012-2021)?
- Cancer research (21.94%)
- Protein kinase B (13.92%)
- PI3K/AKT/mTOR pathway (11.81%)
In recent papers he was focusing on the following fields of study:
His primary areas of investigation include Cancer research, Protein kinase B, PI3K/AKT/mTOR pathway, Breast cancer and Internal medicine.
His research in Cancer research intersects with topics in Haematopoiesis, Hypoxia, Cancer cell, microRNA and Metastasis.
His biological study spans a wide range of topics, including Targeted therapy, Leukemia and Cell growth.
Silvano Capitani combines subjects such as Immunology, Cell cycle checkpoint, Cell cycle and Pharmacology with his study of PI3K/AKT/mTOR pathway.
The Internal medicine study which covers Oncology that intersects with CA15-3.
His Cell biology research focuses on Signal transduction in particular.
Between 2012 and 2021, his most popular works were:
- Targeting PI3K/AKT/mTOR network for treatment of leukemia. (100 citations)
- Targeting the PI3K/Akt/mTOR signaling pathway in B-precursor acute lymphoblastic leukemia and its therapeutic potential. (74 citations)
- Activity of the novel mTOR inhibitor Torin-2 in B-precursor acute lymphoblastic leukemia and its therapeutic potential to prevent Akt reactivation (42 citations)
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