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Tomas Hudlicky

Tomas Hudlicky

D-Index & Metrics

Chemistry

D-Index
67
Citations
15501
World Ranking
6923
National Ranking
184

Research.com Recognitions

  • 2013 - Fellow of the Royal Society of Canada Academy of Science
  • 1981 - Fellow of Alfred P. Sloan Foundation

Overview

Tomas Hudlicky is affiliated with Brock University in Canada and specializes in research spanning Chemistry, Pharmacology, Toxicology and Pharmaceutics, and Medicine. Their work focuses primarily on alkaloids, with significant contributions to the synthesis and pharmacology of these compounds. The key topics covered in their research include:

  • Alkaloids: synthesis and pharmacology
  • Chemical synthesis and alkaloids
  • Cholinesterase and Neurodegenerative Diseases
  • Berberine and alkaloids research
  • Synthesis and Biological Activity
  • Synthetic Organic Chemistry Methods
  • Synthesis of Organic Compounds

Their publication record features articles in prominent journals and venues such as:

  • Tetrahedron
  • Molecules
  • "The 'Alkaloids. Chemistry and biology" and "the 'alkaloids. Chemistry and biology"
  • Angewandte Chemie International Edition
  • Synthesis

Notable recent papers include:

  • "Morphine alkaloids: History, biology, and synthesis" (2021, The 'Alkaloids. Chemistry and biology/'the 'alkaloids. Chemistry and biology)
  • "Withdrawal: 'Organic synthesis - Where now?' is thirty years old. A reflection on the current state of affair" (2020, Angewandte Chemie International Edition)
  • "Synthesis and biological evaluation of 10-benzyloxy-Narciclasine" (2021, Tetrahedron)
  • "Total Synthesis of Methyl 1,5,8-Trimethoxy-1H-isochromene-3-carboxylate and Its Derivatives via Palladium-Catalyzed Annulation of 2-Alkynylbenzaldehydes" (2021, Synthesis)
  • "Sequential enzymatic and electrochemical functionalization of bromocyclohexadienediols: Application to the synthesis of (−)-conduritol C" (2020, Tetrahedron)

Frequent collaborators in their research include:

  • Liqin Du
  • Alexander Kornienko
  • Jared Thomson
  • Juana Goulart Stollmaier
  • Mary Ann A. Endoma-Arias

Tomas Hudlicky's scientific contributions are recognized through honors such as:

  • Fellow of the Royal Society of Canada (2013, Academy of Science)
  • Fellow of Alfred P. Sloan Foundation (1981)

Best Publications

  • Use of cyclopropanes and their derivatives in organic synthesis

    Henry N. C. Wong;Moon Yuen Hon;Chun Wah Tse;Yu Chi Yip

  • Modern Methods of Monosaccharide Synthesis from Non-Carbohydrate Sources.

    Tomas Hudlicky;David A. Entwistle;Kevin K. Pitzer;Andrew J. Thorpe

  • Applications of biotransformations and biocatalysis to complexity generation in organic synthesis.

    Tomas Hudlicky;Josephine W. Reed

  • Anionic approaches to the construction of cyclopentanoids

    Tomas Hudlicky;John D. Price

  • Completion of the seven-step pathway from tabersonine to the anticancer drug precursor vindoline and its assembly in yeast

    Yang Qu;Michael L. A. E. Easson;Jordan Froese;Razvan Simionescu

  • Total synthesis and biological evaluation of Amaryllidaceae alkaloids: narciclasine, ent-7-deoxypancratistatin, regioisomer of 7-deoxypancratistatin, 10b-epi-deoxypancratistatin, and truncated derivatives.

    Tomas Hudlicky;Uwe Rinner;David Gonzalez;Hulya Akgun;Hulya Akgun;Hulya Akgun

  • Design Constraints in Practical Syntheses of Complex Molecules: Current Status, Case Studies with Carbohydrates and Alkaloids, and Future Perspectives.

    Tomas Hudlicky

  • From Discovery to Application: 50 Years of the Vinylcyclopropane–Cyclopentene Rearrangement and Its Impact on the Synthesis of Natural Products

    Tomas Hudlicky;Josephine W. Reed

  • Enantioselective synthesis through microbial oxidation of arenes. 1. Efficient preparation of terpene and prostanoid synthons

    Tomas. Hudlicky;Hector. Luna;Graciela. Barbieri;Lawrence D. Kwart

  • Microbial oxidation of chloroaromatics in the enantiodivergent synthesis of pyrrolizidine alkaloids: trihydroxyheliotridanes

    Tomas Hudlicky;Hector Luna;John D. Price;Fan Rulin

  • Efficient and enantiodivergent synthesis of (+)- and (-)-pinitol

    Tomas Hudlicky;John D. Price;Fan Rulin;Toshiya Tsunoda

  • A short synthesis of (+)-Lycoricidine

    Tomas Hudlicky;Horacio F. Olivo

  • First Total Synthesis of (+)-Pancratistatin: An Unusual Set of Problems

    Xinrong Tian;Tomas Hudlicky;Kurt Koenigsberger

  • Organic Synthesis: Theory and Applications

    Tomas Hudlicky

  • Cyclopentene annulation via intramolecular addition of diazoketones to 1,3-dienes. Applications to the synthesis of cyclopentanoid terpenes

    Tomas Hudlicky;Francis F. Koszyk;Toni M. Kutchan;Jagdish P. Sheth

  • Celebrating 20 Years of SYNLETT - Special Account Onthe Merits of Biocatalysis and the Impact of Arene cis-Dihydrodiolson Enantioselective Synthesis

    Tomas Hudlicky;Josephine W. Reed

  • Toluene Dioxygenase-Mediated cis-Dihydroxylation of Aromatics in Enantioselective Synthesis. Asymmetric Total Syntheses of Pancratistatin and 7-Deoxypancratistatin, Promising Antitumor Agents1

    Tomas Hudlicky;Xinrong Tian;Kurt Königsberger;Rakesh Maurya

  • Chemoenzymatic synthesis of inositols, conduritols, and cyclitol analogues.

    Jan Duchek;David R Adams;Tomas Hudlicky

  • Toward a ‘reagent-free’ synthesis

    Tomas Hudlicky;Dean A. Frey;Lukasz Koroniak;Christopher D. Claeboe

  • Microbial Oxidation of Aromatics in Enantiocontrolled Synthesis. 3. Design of Amino Cyclitols (exo-Nitrogenous) and Total Synthesis of (+)-Lycoricidine via Acylnitrosyl Cycloaddition to Polarized 1-Halo-1,3-cyclohexadienes

    Tomas Hudlicky;Horacio F. Olivo;Bryan McKibben

  • Selective reduction of α,β-unsaturated esters in the presence of olefins

    T. Hudlicky;G. Sinai-Zingde;M.G. Natchus

Frequent Co-Authors

Khalil A. Abboud
Khalil A. Abboud University of Florida
Ion Ghiviriga
Ion Ghiviriga University of Florida
Edmond I. Eger
Edmond I. Eger University of California, San Francisco
Brindaban C. Ranu
Brindaban C. Ranu Indian Association for the Cultivation of Science
George R. Pettit
George R. Pettit Arizona State University
James McNulty
James McNulty McMaster University
David T. Gibson
David T. Gibson The University of Texas at Austin
Wolfgang Oppolzer
Wolfgang Oppolzer University of Geneva
Alexander Kornienko
Alexander Kornienko Texas State University
Johann Mulzer
Johann Mulzer University of Vienna

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