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Peggy Scherle

D-Index & Metrics

Biology and Biochemistry

D-Index
63
Citations
20180
World Ranking
10020
National Ranking
4387

Peggy Scherle publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Peggy Scherle sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 223 publications — 58th percentile

58% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Peggy Scherle D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Peggy Scherle sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 63 D-Index — 49th percentile

49% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Peggy Scherle is affiliated with Incyte in the United States. Their research predominantly spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with significant focus on Molecular Biology, Oncology, Pathology and Forensic Medicine, Genetics, and Hematology as subfields.

The scientist's work extensively covers several key topics including cancer-related gene regulation, protein degradation and inhibitors, chromatin remodeling and cancer, cancer mechanisms and therapy, peptidase inhibition and analysis, CAR-T cell therapy research, and chronic lymphocytic leukemia research.

Among notable recent papers associated with Peggy Scherle are the following:

  • INCB054828 (pemigatinib), a potent and selective inhibitor of fibroblast growth factor receptors 1, 2, and 3, displays activity against genetically defined tumor models, 2020, published in PLoS ONE
  • A human CD137×PD-L1 bispecific antibody promotes anti-tumor immunity via context-dependent T cell costimulation and checkpoint blockade, 2021, published in Nature Communications
  • PRMT5 Inhibition Modulates E2F1 Methylation and Gene-Regulatory Networks Leading to Therapeutic Efficacy in JAK2V617F-Mutant MPN, 2020, published in Cancer Discovery
  • Targeting MYCN-expressing triple-negative breast cancer with BET and MEK inhibitors, 2020, published in Science Translational Medicine
  • Discovery of Pemigatinib: A Potent and Selective Fibroblast Growth Factor Receptor (FGFR) Inhibitor, 2021, published in Journal of Medicinal Chemistry

Frequent co-authors of Peggy Scherle include Kris Vaddi, Neha Bhagwat, Robert A. Baiocchi, Andrew P. Combs, and Lapo Alinari. Collaborative works with these colleagues range in publication count from 16 to 47.

Publications by the scientist appear primarily in venues such as Cancer Research, Blood, Molecular Cancer Therapeutics, Blood Advances, and PLoS ONE, reflecting the focus on cancer biology and hematology.

Best Publications

  • IDENTIFICATION OF A NOVEL INHIBITOR OF MITOGEN-ACTIVATED PROTEIN KINASE KINASE

    Margaret F. Favata;Kurumi Y. Horiuchi;Elizabeth J. Manos;Andrea J. Daulerio

  • Preclinical characterization of the selective JAK1/2 inhibitor INCB018424: therapeutic implications for the treatment of myeloproliferative neoplasms.

    Alfonso Quintás-Cardama;Kris Vaddi;Phillip Liu;Taghi Manshouri

  • Mechanism of tumor rejection with doublets of CTLA-4, PD-1/PD-L1, or IDO blockade involves restored IL-2 production and proliferation of CD8 + T cells directly within the tumor microenvironment

    Stefani Spranger;Holly K Koblish;Brendan Horton;Peggy A Scherle

  • Selective inhibition of IDO1 effectively regulates mediators of antitumor immunity

    Xiangdong Liu;Niu Shin;Holly K. Koblish;Gengjie Yang

  • Selective Inhibition of JAK1 and JAK2 Is Efficacious in Rodent Models of Arthritis: Preclinical Characterization of INCB028050

    Jordan S. Fridman;Peggy A. Scherle;Robert Collins;Timothy C. Burn

  • MEK inhibitors: the chemistry and biological activity of U0126, its analogs, and cyclization products.

    John V. Duncia;Joseph B. Santella;C.Anne Higley;William J. Pitts

  • Targeting ADAM-mediated ligand cleavage to inhibit HER3 and EGFR pathways in non-small cell lung cancer

    Bin Bing S Zhou;Michael Peyton;Biao He;Changnian Liu

  • Inhibition of Mitogen-Activated Protein Kinase Kinase Blocks T Cell Proliferation But Does Not Induce or Prevent Anergy

    Dimuthu R. DeSilva;Elizabeth A. Jones;Margaret F. Favata;Bruce D. Jaffee

  • CCL2 mediates cross-talk between cancer cells and stromal fibroblasts that regulates breast cancer stem cells

    Akihiro Tsuyada;Amy Chow;Jun Wu;George Somlo

  • Inhibition of MAP kinase kinase prevents cytokine and prostaglandin E2 production in lipopolysaccharide-stimulated monocytes.

    Peggy A. Scherle;Elizabeth A. Jones;Margaret F. Favata;Andrea J. Daulerio

  • Hydroxyamidine Inhibitors of Indoleamine-2,3-dioxygenase Potently Suppress Systemic Tryptophan Catabolism and the Growth of IDO-Expressing Tumors

    Holly K. Koblish;Michael J. Hansbury;Kevin J. Bowman;Gengjie Yang

  • Targeting the mechanisms of tumoral immune tolerance with small-molecule inhibitors

    Alexander J. Muller;Peggy A. Scherle

  • First-in-Human Phase I Study of the Oral Inhibitor of Indoleamine 2,3-Dioxygenase-1 Epacadostat (INCB024360) in Patients with Advanced Solid Malignancies.

    Gregory L. Beatty;Peter J. O'Dwyer;Jason Clark;Jack G. Shi

  • Discovery of potent competitive inhibitors of indoleamine 2,3-dioxygenase with in vivo pharmacodynamic activity and efficacy in a mouse melanoma model.

    Eddy W. Yue;Brent Douty;Brian Wayland;Michael Bower

  • INCB24360 (Epacadostat), a Highly Potent and Selective Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitor for Immuno-oncology

    Eddy W. Yue;Richard Sparks;Padmaja Polam;Dilip Modi

  • Phase 2 study of the JAK kinase inhibitor ruxolitinib in patients with refractory leukemias, including postmyeloproliferative neoplasm acute myeloid leukemia

    Alireza Eghtedar;Srdan Verstovsek;Zeev Estrov;Jan Burger

  • Indoleamine 2,3-Dioxygenase and Its Therapeutic Inhibition in Cancer.

    George C. Prendergast;George C. Prendergast;William Paul Malachowski;Arpita Mondal;Peggy Scherle

  • Ly-GDI, a GDP-dissociation inhibitor of the RhoA GTP-binding protein, is expressed preferentially in lymphocytes

    Peggy Scherle;Timothy Behrens;Louis M. Staudt

  • Discovery and pharmacological characterization of a novel rodent-active CCR2 antagonist, INCB3344.

    Carrie M. Brodmerkel;Reid Huber;Maryanne Covington;Sharon Diamond

  • Identification of ADAM10 as a major source of HER2 ectodomain sheddase activity in HER2 overexpressing breast cancer cells.

    Phillip C.C. Liu;Xiangdong Liu;Yanlong Li;Maryanne Covington

Frequent Co-Authors

Robert C. Newton
Robert C. Newton Incyte (United States)
James M. Trzaskos
James M. Trzaskos Bristol-Myers Squibb (Germany)
William V. Williams
William V. Williams GlaxoSmithKline (United Kingdom)
Srdan Verstovsek
Srdan Verstovsek The University of Texas MD Anderson Cancer Center
Jennifer A. Pietenpol
Jennifer A. Pietenpol Vanderbilt University Medical Center
Selina Chen-Kiang
Selina Chen-Kiang Cornell University
Thomas F. Gajewski
Thomas F. Gajewski University of Chicago
Taha Merghoub
Taha Merghoub Cornell University
Jihye Paik
Jihye Paik Cornell University
Robert A. Copeland
Robert A. Copeland Accent Therapeutics (United States)

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Best Scientists Citing Peggy Scherle

Srdan Verstovsek

Srdan Verstovsek

The University of Texas MD Anderson Cancer Center

Publications: 59

George C. Prendergast

George C. Prendergast

Lankenau Institute for Medical Research

Publications: 54

Alexander J. Muller

Alexander J. Muller

Lankenau Institute for Medical Research

Publications: 46

Ruben A. Mesa

Ruben A. Mesa

The University of Texas Health Science Center at San Antonio

Publications: 34

Thomas F. Gajewski

Thomas F. Gajewski

University of Chicago

Publications: 30

Benoît Van den Eynde

Benoît Van den Eynde

Ludwig Cancer Research

Publications: 30

Carl P. Blobel

Carl P. Blobel

Cornell University

Publications: 27

Yoshiya Tanaka

Yoshiya Tanaka

University of Occupational and Environmental Health Japan

Publications: 25

Claire N. Harrison

Claire N. Harrison

Guy's and St Thomas' NHS Foundation Trust

Publications: 24

Chuen-Mao Yang

Chuen-Mao Yang

Chang Gung University

Publications: 22

Ross L. Levine

Ross L. Levine

Memorial Sloan Kettering Cancer Center

Publications: 21

Paul Dent

Paul Dent

Virginia Commonwealth University

Publications: 20

Lars Edvinsson

Lars Edvinsson

Lund University

Publications: 20

Stefani Spranger

Stefani Spranger

MIT

Publications: 19

Alessandro M. Vannucchi

Alessandro M. Vannucchi

University of Florence

Publications: 19

Jedd D. Wolchok

Jedd D. Wolchok

Cornell University

Publications: 18

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