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George C. Prendergast

D-Index & Metrics

Biology and Biochemistry

D-Index
97
Citations
31433
World Ranking
1765
National Ranking
975

Medicine

D-Index
97
Citations
31371
World Ranking
9368
National Ranking
4830

George C. Prendergast publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where George C. Prendergast sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 327 publications — 82nd percentile

82% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

George C. Prendergast D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where George C. Prendergast sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 97 D-Index — 91st percentile

91% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

George C. Prendergast is affiliated with the Lankenau Institute for Medical Research in the United States. Their research spans several interconnected fields with a focus on medicine, biochemistry, genetics, molecular biology, and neuroscience.

The main fields of study in George C. Prendergast's work include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology
  • Neuroscience

They have contributed to subfields such as molecular biology, immunology, biological psychiatry, neurology, and gastroenterology.

Their research addresses a variety of scientific topics, with significant emphasis on:

  • Tryptophan and brain disorders
  • Gut microbiota and health
  • Neuroinflammation and neurodegeneration mechanisms
  • Immune cell function and interaction
  • Immune cells in cancer
  • Gastrointestinal motility and disorders
  • Cancer, hypoxia, and metabolism

George C. Prendergast's publication record includes work in prominent venues such as:

  • Cancer Research
  • The Journal of Immunology
  • Frontiers in Immunology
  • Clinical Cancer Research
  • Methods in Cell Biology

Notable recent papers authored or co-authored by George C. Prendergast include:

  • "Differential Roles of IDO1 and IDO2 in T and B Cell Inflammatory Immune Responses," 2020, Frontiers in Immunology
  • "Advanced Age Increases Immunosuppression in the Brain and Decreases Immunotherapeutic Efficacy in Subjects with Glioblastoma," 2020, Clinical Cancer Research
  • "Dietary L-Tryptophan Consumption Determines the Number of Colonic Regulatory T Cells and Susceptibility to Colitis via GPR15," 2023, Nature Communications
  • "The FDA-Approved Anthelmintic Pyrvinium Pamoate Inhibits Pancreatic Cancer Cells in Nutrient-Depleted Conditions by Targeting the Mitochondria," 2021, Molecular Cancer Therapeutics
  • "IDO1 Signaling through GCN2 in a Subpopulation of Gr-1+ Cells Shifts the IFNγ/IL6 Balance to Promote Neovascularization," 2021, Cancer Immunology Research

Frequent co-authors in their research collaborations include:

  • Alexander J. Muller
  • James B. DuHadaway
  • Sunil Thomas
  • Laura Mandik-Nayak
  • Souvik Dey

Best Publications

  • Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy.

    Alexander J Muller;James B DuHadaway;P Scott Donover;Erika Sutanto-Ward

  • Recognition by Max of its cognate DNA through a dimeric b/HLH/Z domain.

    Adrian R. Ferré-D'Amaré;George C. Prendergast;George C. Prendergast;Edward B. Ziff;Stephen K. Burley;Stephen K. Burley

  • BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression

    David E. Jensen;Monja Proctor;Sandra T. Marquis;Heather Perry Gardner

  • Methylation-sensitive sequence-specific DNA binding by the c-Myc basic region.

    George C. Prendergast;Edward B. Ziff

  • Association of Myn, the murine homolog of max, with c-Myc stimulates methylation-sensitive DNA binding and ras cotransformation.

    George C. Prendergast;George C. Prendergast;Deirdre Lawe;Deirdre Lawe;Edward B. Ziff;Edward B. Ziff

  • Aryl hydrocarbon receptor control of a disease tolerance defence pathway

    Alban Bessede;Alban Bessede;Marco Gargaro;Maria T. Pallotta;Davide Matino

  • Inhibition of Indoleamine 2,3-Dioxygenase in Dendritic Cells by Stereoisomers of 1-Methyl-Tryptophan Correlates with Antitumor Responses

    De Yan Hou;Alexander J. Muller;Madhav D. Sharma;James DuHadaway

  • Mechanisms of apoptosis by c-Myc.

    George C Prendergast

  • Classification of current anticancer immunotherapies

    Lorenzo Galluzzi;Erika Vacchelli;José Manuel Bravo-San Pedro;Aitziber Buqué

  • Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophan

    Richard Metz;James B. DuHadaway;Uma Kamasani;Lisa Laury-Kleintop

  • Indoleamine 2,3-dioxygenase in T-cell tolerance and tumoral immune escape.

    Jessica B. Katz;Alexander J. Muller;Alexander J. Muller;George C. Prendergast;George C. Prendergast

  • Indoleamine 2,3-dioxygenase pathways of pathogenic inflammation and immune escape in cancer

    George C. Prendergast;George C. Prendergast;Courtney Smith;Sunil Thomas;Laura Mandik-Nayak

  • Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models.

    N Takahashi;L Duprez;S Grootjans;A Cauwels

  • Discovery of IDO1 Inhibitors: From Bench to Bedside

    George C. Prendergast;William P. Malachowski;James B. DuHadaway;Alexander J. Muller

  • The polyproline region of p53 is required to activate apoptosis but not growth arrest.

    Daitoku Sakamuro;Peter Sabbatini;Eileen White;George C Prendergast

  • BIN1 is a novel MYC-interacting protein with features of a tumour suppressor.

    Daitoku Sakamuro;Katharine J. Elliott;Robert Wechsler-Reya;George C. Prendergast

  • Plasminogen activator inhibitor-1 gene-deficient mice. I. Generation by homologous recombination and characterization.

    P Carmeliet;L Kieckens;L Schoonjans;B Ream

  • c-Myc represses transcription in vivo by a novel mechanism dependent on the initiator element and Myc box II.

    Lin-Heng Li;C. Nerlov;G. Prendergast;D. Macgregor

  • Immune escape as a fundamental trait of cancer: focus on IDO.

    G C Prendergast;G C Prendergast

  • IDO inhibits a tryptophan sufficiency signal that stimulates mTOR: A novel IDO effector pathway targeted by D-1-methyl-tryptophan

    Richard Metz;Sonja Rust;James B. DuHadaway;Mario R. Mautino

Frequent Co-Authors

Alexander J. Muller
Alexander J. Muller Lankenau Institute for Medical Research
Andrew L. Mellor
Andrew L. Mellor Newcastle University
David H. Munn
David H. Munn Augusta University
Edward B. Ziff
Edward B. Ziff New York University
Jackson B. Gibbs
Jackson B. Gibbs George Washington University
Suzanne Ostrand-Rosenberg
Suzanne Ostrand-Rosenberg University of Maryland, Baltimore County
Charles J. Yeo
Charles J. Yeo Thomas Jefferson University
Jonathan R. Brody
Jonathan R. Brody Thomas Jefferson University
Richard G. Pestell
Richard G. Pestell Baruch S. Blumberg Institute
Eileen White
Eileen White Rutgers, The State University of New Jersey

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