D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 62 Citations 16,472 118 World Ranking 6923 National Ranking 3219

Overview

What is he best known for?

The fields of study Jackson B. Gibbs is best known for:

  • Enzyme
  • Gene
  • Amino acid

Jackson B. Gibbs usually deals with Human health and limits it to topics linked to Environmental health and Population. His Environmental health research extends to the thematically linked field of Population. His study in Size-exclusion chromatography is interdisciplinary in nature, drawing from both Guanosine triphosphate, GTP' and Signal transduction, GTPase-activating protein, G protein. Jackson B. Gibbs conducted interdisciplinary study in his works that combined Guanosine triphosphate and GTPase. In his works, Jackson B. Gibbs undertakes multidisciplinary study on GTPase and Phosphorylation. Jackson B. Gibbs carries out multidisciplinary research, doing studies in Phosphorylation and Platelet-derived growth factor receptor. He combines Platelet-derived growth factor receptor and Platelet-derived growth factor in his studies. His GTP' study frequently draws connections to other fields, such as Guanosine diphosphate. He conducted interdisciplinary study in his works that combined Signal transduction and SH3 domain.

His most cited work include:

  • Cloning of bovine GAP and its interaction with oncogenic ras p21 (633 citations)
  • Intrinsic GTPase activity distinguishes normal and oncogenic ras p21 molecules. (526 citations)
  • Farnesyltransferase inhibitors: Ras research yields a potential cancer therapeutic (503 citations)

What are the main themes of his work throughout his whole career to date

Borrowing concepts from Molecular biology, Jackson B. Gibbs weaves in ideas under Biochemistry. Jackson B. Gibbs integrates several fields in his works, including Molecular biology and Biochemistry. Enzyme and GTP' are frequently intertwined in his study. His study ties his expertise on Signal transduction together with the subject of Cell biology. His research on Signal transduction frequently links to adjacent areas such as Cell biology. Jackson B. Gibbs conducts interdisciplinary study in the fields of Prenylation and Farnesyltransferase inhibitor through his works. Jackson B. Gibbs integrates many fields, such as Farnesyltransferase inhibitor and Farnesyltransferase, in his works. In his articles, Jackson B. Gibbs combines various disciplines, including Farnesyltransferase and Farnesyl-diphosphate farnesyltransferase. Many of his studies on Farnesyl-diphosphate farnesyltransferase involve topics that are commonly interrelated, such as Prenylation.

Jackson B. Gibbs most often published in these fields:

  • Biochemistry (83.58%)
  • Enzyme (59.70%)
  • Cell biology (35.82%)

What were the highlights of his more recent work (between 2003-2010)?

  • Receptor (80.00%)
  • Kinase (80.00%)
  • Tyrosine kinase (60.00%)

In recent works Jackson B. Gibbs was focusing on the following fields of study:

Receptor is closely attributed to Receptor tyrosine kinase in his work. Many of his studies involve connections with topics such as Receptor and Receptor tyrosine kinase. While working in this field, Jackson B. Gibbs studies both Kinase and MAPK/ERK pathway. He merges MAPK/ERK pathway with Kinase in his study. His Tyrosine kinase study frequently draws connections between related disciplines such as Cell biology. Jackson B. Gibbs frequently studies issues relating to Protein kinase A and Cell biology. As part of his studies on Protein kinase A, he often connects relevant areas like Autophosphorylation. Jackson B. Gibbs performs multidisciplinary study in Autophosphorylation and Tyrosine kinase in his work. His Potency research extends to Biochemistry, which is thematically connected.

Between 2003 and 2010, his most popular works were:

  • Lung Cancer Cell Lines Harboring MET Gene Amplification Are Dependent on Met for Growth and Survival (280 citations)
  • Proceedings from the 2009 genetic syndromes of the Ras/MAPK pathway: From bedside to bench and back (88 citations)
  • MK-2461, a Novel Multitargeted Kinase Inhibitor, Preferentially Inhibits the Activated c-Met Receptor (72 citations)

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Selective inhibition of ras-dependent transformation by a farnesyltransferase inhibitor.

NE Kohl;SD Mosser;SJ deSolms;EA Giuliani.
Science (1993)

801 Citations

Intrinsic GTPase activity distinguishes normal and oncogenic ras p21 molecules.

Jackson B. Gibbs;Irving S. Sigal;Martin Poe;Edward M. Scolnick.
Proceedings of the National Academy of Sciences of the United States of America (1984)

728 Citations

Sequence dependence of protein isoprenylation

S L Moores;M D Schaber;S D Mosser;E Rands.
Journal of Biological Chemistry (1991)

691 Citations

Mechanism-based target identification and drug discovery in cancer research

Jackson B. Gibbs.
Science (2000)

686 Citations

Cloning of bovine GAP and its interaction with oncogenic ras p21

Ursula S. Vogel;Richard A. F. Dixon;Michael D. Schaber;Ronald E. Diehl.
Nature (1988)

668 Citations

Farnesyltransferase inhibitors: Ras research yields a potential cancer therapeutic.

Jackson B. Gibbs;Allen Oliff;Nancy E. Kohl.
Cell (1994)

650 Citations

A Peptidomimetic Inhibitor of Farnesyl:Protein Transferase Blocks the Anchorage-dependent and -independent Growth of Human Tumor Cell Lines

Laura Sepp-Lorenzino;Zhenping Ma;Elaine Rands;Nancy E. Kohl.
Cancer Research (1995)

542 Citations

PDGF induction of tyrosine phosphorylation of GTPase activating protein.

Christopher J. Molloy;Donald P. Bottaro;Timothy P. Fleming;Mark S. Marshall.
Nature (1989)

498 Citations

RAS C-TERMINAL PROCESSING ENZYMES : NEW DRUG TARGETS ?

Jackson B. Gibbs.
Cell (1991)

493 Citations

S. cerevisiae genes IRA1 and IRA2 encode proteins that may be functionally equivalent to mammalian ras GTPase activating protein

Kazuma Tanaka;Masato Nakafuku;Takaya Satoh;Mark S. Marshall.
Cell (1990)

406 Citations

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