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Biology and Biochemistry
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2026

D-Index & Metrics

Discipline name D-Index World Ranking Current World Ranking National Ranking Current National Ranking Publications Citations
Best Scientists 239 71 66 51 48 594 217496
Biology and Biochemistry 240 9 9 7 7 569 220295

Michael S. Brown publications per year

The chart shows the history of publications by Michael S. Brown between 1973 and 2025, highlighting the no. of papers published in each year and offering an overview of the publication velocity of this scholar. Michael S. Brown published across 53 years, from 1973 to 2025, averaging 11.4 papers a year. Output peaked at 24 publications in 1983. 12 of the 606 publications appeared in the last two years.

No. of publications
5 10 15 20
Bar chart. Horizontal axis: year, 1973 to 2025. Vertical axis: number of publications, 0 to 24. Peak 24 publications in 1983. 1973: 3 publications 1974: 11 publications 1975: 17 publications 1976: 16 publications 1977: 11 publications 1978: 9 publications 1979: 22 publications 1980: 16 publications 1981: 17 publications 1982: 20 publications 1983: 24 publications 1984: 12 publications 1985: 21 publications 1986: 16 publications 1987: 23 publications 1988: 16 publications 1989: 12 publications 1990: 20 publications 1991: 14 publications 1992: 16 publications 1993: 18 publications 1994: 14 publications 1995: 11 publications 1996: 13 publications 1997: 13 publications 1998: 11 publications 1999: 20 publications 2000: 15 publications 2001: 8 publications 2002: 14 publications 2003: 14 publications 2004: 13 publications 2005: 9 publications 2006: 7 publications 2007: 5 publications 2008: 11 publications 2009: 14 publications 2010: 10 publications 2011: 6 publications 2012: 14 publications 2013: 2 publications 2014: 3 publications 2015: 6 publications 2016: 3 publications 2017: 3 publications 2018: 6 publications 2019: 3 publications 2020: 2 publications 2021: 5 publications 2022: 4 publications 2023: 1 publication 2024: 7 publications 2025: 5 publications
1973 2025

606 publications in total across all disciplines

View publications per year as a table
Michael S. Brown: publications per year, 1973 to 2025
Year Publications
1973 3
1974 11
1975 17
1976 16
1977 11
1978 9
1979 22
1980 16
1981 17
1982 20
1983 24
1984 12
1985 21
1986 16
1987 23
1988 16
1989 12
1990 20
1991 14
1992 16
1993 18
1994 14
1995 11
1996 13
1997 13
1998 11
1999 20
2000 15
2001 8
2002 14
2003 14
2004 13
2005 9
2006 7
2007 5
2008 11
2009 14
2010 10
2011 6
2012 14
2013 2
2014 3
2015 6
2016 3
2017 3
2018 6
2019 3
2020 2
2021 5
2022 4
2023 1
2024 7
2025 5
Total 606
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Michael S. Brown publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Michael S. Brown sits on this spectrum.

No. of scientists
200 400 600 800
Bar chart with 100 bars. Horizontal axis: publications, 47–56 to 1,028+. Vertical axis: number of scientists, 0 to 980. Most scientists, 980, have 127–136 publications. The last bar groups every scientist with 1,028 publications or more. The highlighted bar, 567–576 publications, is where this scientist sits. 47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 413 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 848 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 949 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 840 scientists 207–216 publications: 733 scientists 217–226 publications: 708 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 417 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 196 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 59 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientist 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientist 1,028+ publications: 100 scientists
47–56 publications 1,028+

This scientist: 569 publications — 97th percentile

97% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

View publications distribution as a table
Number of Biology and Biochemistry scientists by publication count, Research.com 2026 ranking edition. Based on 19,587 ranked scientists.
Publications Scientists This scientist
47–56 8
57–66 35
67–76 106
77–86 231
87–96 413
97–106 546
107–116 704
117–126 848
127–136 980
137–146 942
147–156 969
157–166 949
167–176 951
177–186 915
187–196 787
197–206 840
207–216 733
217–226 708
227–236 651
237–246 605
247–256 510
257–266 524
267–276 434
277–286 417
287–296 350
297–306 363
307–316 315
317–326 296
327–336 261
337–346 240
347–356 219
357–366 196
367–376 154
377–386 161
387–396 155
397–406 145
407–416 124
417–426 112
427–436 132
437–446 116
447–456 99
457–466 81
467–476 91
477–486 80
487–496 80
497–506 59
507–516 36
517–526 46
527–536 54
537–546 44
547–556 43
557–566 43
567–576 42 569
577–586 25
587–596 34
597–606 23
607–616 33
617–626 31
627–636 27
637–646 25
647–656 28
657–666 34
667–676 18
677–686 16
687–696 10
697–706 12
707–716 21
717–726 12
727–736 12
737–746 10
747–756 7
757–766 13
767–776 15
777–786 13
787–796 9
797–806 9
807–816 7
817–826 4
827–836 9
837–846 7
847–856 3
857–866 5
867–876 5
877–886 11
887–896 3
897–906 4
907–916 7
917–926 5
927–936 6
937–946 6
947–956 3
957–966 7
967–976 2
977–986 2
987–996 1
997–1,006 5
1,007–1,016 2
1,017–1,026 2
1,027 1
1,028+ 100
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Michael S. Brown D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Michael S. Brown sits on this spectrum.

No. of scientists
250 500 750 1,000 1,250
Bar chart with 65 bars. Horizontal axis: D-Index, 40–41 to 167+. Vertical axis: number of scientists, 0 to 1,253. Most scientists, 1,253, have 58–59 D-Index. The last bar groups every scientist with 167 D-Index or more. The highlighted bar, 167+ D-Index, is where this scientist sits. 40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 316 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 899 scientists 52–53 D-Index: 1,025 scientists 54–55 D-Index: 1,149 scientists 56–57 D-Index: 1,235 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,162 scientists 62–63 D-Index: 1,130 scientists 64–65 D-Index: 1,031 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 714 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 71 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40–41 D-Index 167+

This scientist: 240 D-Index — 100th percentile

100% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

View D-Index distribution as a table
Number of Biology and Biochemistry scientists by D-index, Research.com 2026 ranking edition. Based on 19,587 ranked scientists.
D-Index Scientists This scientist
40–41 80
42–43 183
44–45 316
46–47 504
48–49 718
50–51 899
52–53 1,025
54–55 1,149
56–57 1,235
58–59 1,253
60–61 1,162
62–63 1,130
64–65 1,031
66–67 897
68–69 814
70–71 714
72–73 709
74–75 596
76–77 512
78–79 473
80–81 412
82–83 373
84–85 358
86–87 285
88–89 273
90–91 227
92–93 208
94–95 193
96–97 153
98–99 157
100–101 148
102–103 120
104–105 113
106–107 100
108–109 86
110–111 67
112–113 71
114–115 73
116–117 64
118–119 53
120–121 60
122–123 54
124–125 43
126–127 38
128–129 49
130–131 26
132–133 18
134–135 23
136–137 32
138–139 32
140–141 27
142–143 19
144–145 22
146–147 12
148–149 16
150–151 14
152–153 10
154–155 13
156–157 10
158–159 7
160–161 9
162–163 13
164–165 4
166 4
167+ 98 240
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Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in United States Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Biology and Biochemistry in United States Leader Award
  • 2023 - Research.com Biology and Biochemistry in United States Leader Award
  • 2003 - Albany Medical Center Prize in Medicine and Biomedical Research
  • 1999 - Warren Alpert Foundation Prize For their research in the development of statins which lower the level of cholesterol in the heart.
  • 1990 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1988 - US President's National Medal of Science "For their historic discovery of the basic mechanisms controlling cholesterol metabolism, opening the way to a new pharmacologic approach to the treatment of cardiovascular disease, the leading cause of death and disability in the Western world.", Presented by President Reagan at a White House Ceremony on July 15, 1988. Awarded jointly with Dr. Joseph L. Goldstein, University of Texas Southwestern Medical Center.
  • 1987 - Member of the National Academy of Medicine (NAM)
  • 1985 - Albert Lasker Award for Basic Medical Research, Lasker Foundation
  • 1985 - William Allan Award, the American Society of Human Genetics
  • 1985 - Nobel Prize for their discoveries concerning the regulation of cholesterol metabolism
  • 1984 - Louisa Gross Horwitz Prize, Columbia University
  • 1981 - Fellow of the American Academy of Arts and Sciences
  • 1981 - Canada Gairdner International Award
  • 1979 - Richard Lounsbery Award, National Academy of Sciences and the French Academy of Sciences for their work in cholesterol biosynthesis.
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Michael S. Brown is affiliated with The University of Texas Southwestern Medical Center in the United States. Their scholarly contributions span extensive research in the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Within these areas, the scientist has focused on specialized subfields including Molecular Biology, Surgery, Epidemiology, Economics and Econometrics, and Cell Biology.

The scientific topics most frequently addressed in their work include Cholesterol and Lipid Metabolism, Lipid Membrane Structure and Behavior, RNA and protein synthesis mechanisms, Extracellular vesicles in disease, Sphingolipid Metabolism and Signaling, Cellular transport and secretion, and Endoplasmic Reticulum Stress and Disease.

Among their recent publications are the following papers:

  • Last step in the path of LDL cholesterol from lysosome to plasma membrane to ER is governed by phosphatidylserine (2020) in Proceedings of the National Academy of Sciences
  • Interplay between Asters/GRAMD1s and phosphatidylserine in intermembrane transport of LDL cholesterol (2022) in Proceedings of the National Academy of Sciences
  • Scap structures highlight key role for rotation of intertwined luminal loops in cholesterol sensing (2021) in Cell
  • Unexpected role for IGF-1 in starvation: Maintenance of blood glucose (2022) in Proceedings of the National Academy of Sciences
  • A novel mechanistic framework for precise sequence replacement using reverse transcriptase and diverse CRISPR-Cas systems (2022) in bioRxiv (Cold Spring Harbor Laboratory)

Frequent co-authors collaborating with Michael S. Brown include:

  • Joseph L. Goldstein
  • Michael Trinh
  • Gonçalo Vale
  • Jeffrey G. McDonald
  • Joachim Seemann

The scientist has published frequently in these venues:

  • Proceedings of the National Academy of Sciences
  • arXiv (Cornell University)
  • Cell
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Defense Analytics and Logistics

Their work has been recognized with numerous awards:

  • Albany Medical Center Prize in Medicine and Biomedical Research (2003)
  • Warren Alpert Foundation Prize (1999) for research in the development of statins which lower the level of cholesterol in the heart
  • Fellow of the American Association for the Advancement of Science (AAAS) (1990)
  • US President's National Medal of Science (1988) for discovery of basic mechanisms controlling cholesterol metabolism, awarded jointly with Joseph L. Goldstein
  • Member of the National Academy of Medicine (NAM) (1987)
  • Albert Lasker Award for Basic Medical Research (1985)
  • William Allan Award, the American Society of Human Genetics (1985)
  • Nobel Prize (1985) for discoveries concerning the regulation of cholesterol metabolism
  • Louisa Gross Horwitz Prize, Columbia University (1984)
  • Canada Gairdner International Award (1981)
  • Fellow of the American Academy of Arts and Sciences (1981)
  • Richard Lounsbery Award, National Academy of Sciences and the French Academy of Sciences (1979) for work in cholesterol biosynthesis
  • Member of the Association of American Physicians

Best Publications

  • Regulation of the mevalonate pathway.

    Joseph L. Goldstein;Michael S. Brown

  • A receptor-mediated pathway for cholesterol homeostasis.

    Michael S. Brown;Joseph L. Goldstein

  • SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

    Jay D. Horton;Joseph L. Goldstein;Michael S. Brown

  • The SREBP Pathway: Regulation of Cholesterol Metabolism by Proteolysis of a Membrane-Bound Transcription Factor

    Michael S Brown;Joseph L Goldstein

  • Lipoprotein metabolism in the macrophage: Implications for cholesterol deposition in atherosclerosis

    Michael S. Brown;Joseph L. Goldstein

  • Binding Site on Macrophages that Mediates Uptake and Degradation of Acetylated Low Density Lipoprotein, Producing Massive Cholesterol Deposition

    Joseph L. Goldstein;Y. K. Ho;Sandip K. Basu;Michael S. Brown

  • Knowledge-based analysis of microarray gene expression data by using support vector machines

    Michael P. S. Brown;William Noble Grundy;David Lin;Nello Cristianini

  • Coated pits, coated vesicles, and receptor-mediated endocytosis

    Joseph L. Goldstein;Richard G. W. Anderson;Michael S. Brown

  • HIDDEN MARKOV MODELS IN COMPUTATIONAL BIOLOGY: APPLICATIONS TO PROTEIN MODELING

    Anders Krogh;Michael Brown;I. S Mian;Kimmen Sjolander

  • Receptor-mediated endocytosis of low-density lipoprotein in cultured cells

    Joseph L. Goldstein;Sandip K. Basu;Michael S. Brown

  • Protein Sensors for Membrane Sterols

    Joseph L. Goldstein;Russell A. DeBose-Boyd;Michael S. Brown

  • Receptor-Mediated Endocytosis: Concepts Emerging from the LDL Receptor System

    Joseph L. Goldstein;Michael S. Brown;Richard G. W. Anderson;David W. Russell

  • ER Stress Induces Cleavage of Membrane-Bound ATF6 by the Same Proteases that Process SREBPs

    Jin Ye;Robert B Rawson;Ryutaro Komuro;Xi Chen

  • Binding and Degradation of Low Density Lipoproteins by Cultured Human Fibroblasts COMPARISON OF CELLS FROM A NORMAL SUBJECT AND FROM A PATIENT WITH HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA

    Joseph L. Goldstein;Michael S. Brown

  • Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery.

    Shun Ishibashi;Michael S Brown;Joseph L Goldstein;Robert D. Gerard

  • Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRα and LXRβ

    Joyce J. Repa;Guosheng Liang;Jiafu Ou;Yuriy Bashmakov

  • The human LDL receptor: A cysteine-rich protein with multiple Alu sequences in its mRNA

    Tokuo Yamamoto;C. Geoffrey Davis;Michael S. Brown;Wolfgang J. Schneider

  • A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood

    Michael S. Brown;Joseph L. Goldstein

  • Ablation in Mice of the mTORC Components raptor, rictor, or mLST8 Reveals that mTORC2 Is Required for Signaling to Akt-FOXO and PKCα, but Not S6K1

    David A. Guertin;David A. Guertin;Deanna M. Stevens;Carson C. Thoreen;Aurora A. Burds

  • Multivalent feedback regulation of HMG CoA reductase, a control mechanism coordinating isoprenoid synthesis and cell growth

    Michael S. Brown;Joseph L. Goldstein

Frequent Co-Authors

Joseph L. Goldstein
Joseph L. Goldstein The University of Texas Southwestern Medical Center
Richard G. W. Anderson
Richard G. W. Anderson The University of Texas Southwestern Medical Center
Jay D. Horton
Jay D. Horton The University of Texas Southwestern Medical Center
Robert E. Hammer
Robert E. Hammer The University of Texas Southwestern Medical Center
David W. Russell
David W. Russell University of Washington
Miguel C. Seabra
Miguel C. Seabra Universidade Nova de Lisboa
Thomas C. Südhof
Thomas C. Südhof Stanford University
Joachim Herz
Joachim Herz The University of Texas Southwestern Medical Center
Juro Sakai
Juro Sakai University of Tokyo
Johann Deisenhofer
Johann Deisenhofer The University of Texas Southwestern Medical Center

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