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Hiroaki Ohno

Hiroaki Ohno

D-Index & Metrics

Chemistry

D-Index
65
Citations
12299
World Ranking
7831
National Ranking
521

Overview

Hiroaki Ohno is affiliated with Kyoto University in Japan and has contributed extensively to the field of chemistry. Their research encompasses several interconnected disciplines, with a strong focus on organic chemistry, molecular biology, materials chemistry, immunology, and radiology, nuclear medicine and imaging. These areas reflect a multidisciplinary approach to chemical and biological science.

The main fields of study in Ohno's research include:

  • Chemistry

Ohno's work extends into more specialized subfields, such as:

  • Organic Chemistry
  • Molecular Biology
  • Materials Chemistry
  • Immunology
  • Radiology, Nuclear Medicine and Imaging

Their primary research topics showcase a focus on catalytic and crystallographic methods, including:

  • Catalytic Alkyne Reactions
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Monoclonal and Polyclonal Antibodies Research
  • Catalytic C-H Functionalization Methods
  • Cyclopropane Reaction Mechanisms
  • Chemical Synthesis and Analysis

Ohno has published papers in several notable venues, frequently contributing to journals such as:

  • The Cambridge Structural Database
  • Chemistry - A European Journal
  • The Journal of Organic Chemistry
  • Angewandte Chemie International Edition
  • Angewandte Chemie

Frequent co-authors in their work include:

  • Shinsuke Inuki
  • Shinya Oishi
  • Norihito Arichi
  • Luca C. Greiner
  • Hiroki Akiba

Significant recent publications from Ohno include:

  • "Maternal gut microbiota in pregnancy influences offspring metabolic phenotype in mice," 2020, Science
  • "Host metabolic benefits of prebiotic exopolysaccharides produced by Leuconostoc mesenteroides," 2023, Gut Microbes
  • "Total Synthesis of Zephycarinatines via Photocatalytic Reductive Radical ipso-Cyclization," 2020, Angewandte Chemie International Edition
  • "Azido-Alkynes in Gold(I)-Catalyzed Indole Syntheses," 2021, The Chemical Record
  • "Gold(I)-Catalyzed Benzylic C(sp 3 )−H Functionalizations: Divergent Synthesis of Indole[ a ]- and [ b ]-Fused Polycycles," 2022, Angewandte Chemie International Edition

Best Publications

  • Maternal gut microbiota in pregnancy influences offspring metabolic phenotype in mice

    Ikuo Kimura;Ikuo Kimura;Junki Miyamoto;Junki Miyamoto;Ryuji Ohue-Kitano;Ryuji Ohue-Kitano;Keita Watanabe

  • Synthesis and applications of vinylaziridines and ethynylaziridines.

    Hiroaki Ohno

  • Palladium-Catalyzed sp3 C—H Activation of Simple Alkyl Groups: Direct Preparation of Indoline Derivatives from N-Alkyl-2-bromoanilines

    Toshiaki Watanabe;Shinya Oishi;Nobutaka Fujii;Hiroaki Ohno

  • Direct synthesis of fused indoles by gold-catalyzed cascade cyclization of diynes.

    Kimio Hirano;Yusuke Inaba;Naoya Takahashi;Masanao Shimano

  • Palladium-Catalyzed Direct Synthesis of Carbazoles via One-Pot N-Arylation and Oxidative Biaryl Coupling: Synthesis and Mechanistic Study

    Toshiaki Watanabe;Shinya Oishi;Nobutaka Fujii;Hiroaki Ohno

  • Direct Synthesis of 2-(Aminomethyl)indoles through Copper(I)-Catalyzed Domino Three-Component Coupling and Cyclization Reactions

    Hiroaki Ohno;Yusuke Ohta;Shinya Oishi;Nobutaka Fujii

  • Z-selective Horner-Wadsworth-Emmons reaction of ethyl (diarylphosphono)acetates using sodium iodide and DBU

    Kaori Ando;Tohru Oishi;Masahiro Hirama;Hiroaki Ohno

  • Dual gold catalysis: a novel synthesis of bicyclic and tricyclic pyrroles from N-propargyl ynamides.

    Yusuke Tokimizu;Marcel Wieteck;Matthias Rudolph;Shinya Oishi

  • Gold-Catalyzed Cascade Cyclization of (Azido)ynamides: An Efficient Strategy for the Construction of Indoloquinolines

    Yusuke Tokimizu;Shinya Oishi;Nobutaka Fujii;Hiroaki Ohno

  • Gold-Catalyzed Intramolecular Alkyne Cycloisomerization Cascade: Direct Synthesis of Aryl-Annulated[a]carbazoles from Aniline-Substituted Diethynylarenes

    Kimio Hirano;Yusuke Inaba;Toshiaki Watanabe;Shinya Oishi

  • Gold-catalyzed hydroarylation of allenes: a highly regioselective carbon-carbon bond formation producing six-membered rings.

    Toshiaki Watanabe;Shinya Oishi;Nobutaka Fujii;Hiroaki Ohno

  • One-pot synthesis of carbazoles by palladium-catalyzed N-arylation and oxidative coupling.

    Toshiaki Watanabe;Satoshi Ueda;Shinsuke Inuki;Shinya Oishi

  • Construction of nitrogen heterocycles bearing an aminomethyl group by copper-catalyzed domino three-component coupling-cyclization.

    Yusuke Ohta;Hiroaki Chiba;Shinya Oishi;Nobutaka Fujii

  • Palladium(0)-Catalyzed Synthesis of Medium-Sized Heterocycles by Using Bromoallenes as an Allyl Dication Equivalent

    Hiroaki Ohno;Hisao Hamaguchi;Miyo Ohata;Shohei Kosaka

  • Peptide bond mimicry by (E)-alkene and (Z)-fluoroalkene peptide isosteres: synthesis and bioevaluation of α-helical anti-HIV peptide analogues

    Shinya Oishi;Hirotaka Kamitani;Yasuyo Kodera;Kentaro Watanabe

  • Concise synthesis of indole-fused 1,4-diazepines through copper(I)-catalyzed domino three-component coupling-cyclization-N-arylation under microwave irradiation.

    Yusuke Ohta;Hiroaki Chiba;Shinya Oishi;Nobutaka Fujii

  • Structure-activity relationships of cyclic peptide-based chemokine receptor CXCR4 antagonists: disclosing the importance of side-chain and backbone functionalities.

    Satoshi Ueda;Shinya Oishi;Zi-xuan Wang;Takanobu Araki

  • Direct synthesis of quinazolines through copper-catalyzed reaction of aniline-derived benzamidines.

    Yusuke Ohta;Yusuke Tokimizu;Shinya Oishi;Nobutaka Fujii

  • A Thermodynamic Preference of Chiral N-Methanesulfonyl and N-Arenesulfonyl 2,3-cis-3-Alkyl-2-Vinylaziridines over Their 2,3-Trans-Isomers: Useful Palladium(0)-Catalyzed Equilibration Reactions for the Synthesis of (E)-Alkene Dipeptide Isosteres

    Toshiro Ibuka;Norio Mimura;Hiroshi Aoyama;Masako Akaji

  • Gold‐Catalyzed Cascade Reactions of Alkynes for Construction of Polycyclic Compounds

    Hiroaki Ohno

Frequent Co-Authors

Nobutaka Fujii
Nobutaka Fujii Kyoto University
Shinya Oishi
Shinya Oishi Kyoto University
Masao Matsuoka
Masao Matsuoka Kumamoto University
Yoshiji Takemoto
Yoshiji Takemoto Kyoto University
Akira Otaka
Akira Otaka University of Tokushima
Akira Hirasawa
Akira Hirasawa Okayama University
Gozoh Tsujimoto
Gozoh Tsujimoto Kyoto University
Hirokazu Tamamura
Hirokazu Tamamura Tokyo Medical and Dental University
Stephen C. Peiper
Stephen C. Peiper Thomas Jefferson University
A. Stephen K. Hashmi
A. Stephen K. Hashmi Heidelberg University

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