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James McNulty

James McNulty

D-Index & Metrics

Chemistry

D-Index
41
Citations
6175
World Ranking
17769
National Ranking
479

Overview

James McNulty is affiliated with McMaster University in Canada, with a research focus primarily in Chemistry and Agricultural and Biological Sciences. Their work encompasses various subfields, including Organic Chemistry, Plant Science, Molecular Biology, Pharmacology, and Epidemiology.

The scientist has contributed to multiple topics in their research, notably:

  • Chemical synthesis and alkaloids
  • Herpesvirus Infections and Treatments
  • Synthesis of Indole Derivatives
  • Axial and Atropisomeric Chirality Synthesis
  • Alkaloids: synthesis and pharmacology
  • Phytochemistry and biological activities of Ficus species
  • Legume Nitrogen Fixing Symbiosis

James McNulty's publication record includes recent papers such as:

  • "Truncated ring-A amaryllidaceae alkaloid modulates the host cell integrated stress response, exhibiting antiviral activity to HSV-1 and SARSCoV-2," 2023, Scientific Reports
  • "A flavin-dependent monooxygenase produces nitrogenous tomato aroma volatiles using cysteine as a nitrogen source," 2022, Proceedings of the National Academy of Sciences
  • "A Catalytic, Oxidative Synthesis of Olivetol, Methyl Olivetolate and Orthogonally Protected Methyl Ether Derivatives," 2021, SynOpen
  • "Metabolite profiling reveals a role for intercellular dihydrocamalexic acid in the response of mature Arabidopsis thaliana to Pseudomonas syringae," 2021, Phytochemistry
  • "Synthesis of non-nucleoside anti-viral cyclopropylcarboxacyl hydrazones and initial anti-HSV-1 structure-activity relationship studies," 2020, Bioorganic & Medicinal Chemistry Letters

Frequent coauthors collaborating with James McNulty include:

  • David K. Liscombe
  • Christine J. Kempthorne
  • Leonardo D'Aiuto
  • Vishwajit L. Nimgaonkar
  • Paul R. Kinchington

The scientist's research has been published in venues such as:

  • Phytochemistry
  • Proceedings of the National Academy of Sciences
  • Bioorganic & Medicinal Chemistry Letters
  • SynOpen
  • Scientific Reports

Best Publications

  • Dispersion polymerization of styrene in polar solvents. 6. Influence of reaction parameters on particle size and molecular weight in poly(N-vinylpyrrolidone)-stabilized reactions

    Anthony James Paine;Wayne Luymes;James McNulty

  • The first well-defined silver(I)-complex-catalyzed cycloaddition of azides onto terminal alkynes at room temperature.

    James McNulty;Kunal Keskar;Ramesh Vemula

  • The ultrasound promoted Knoevenagel condensation of aromatic aldehydes

    James McNulty;Jennifer A. Steere;Sonja Wolf

  • Selective apoptosis-inducing activity of crinum-type Amaryllidaceae alkaloids

    James McNulty;Jerald J. Nair;Carles Codina;Jaume Bastida

  • Palladium complexes of 1,3,5,7-tetramethyl-2,4,8-trioxa-6-phenyl-6-phosphaadamantane: synthesis, crystal structure and use in the Suzuki and Sonogashira reactions and the alpha-arylation of ketones.

    George Adjabeng;Tim Brenstrum;Christopher S Frampton;Al J Robertson

  • Discovery of a Robust and Efficient Homogeneous Silver(I) Catalyst for the Cycloaddition of Azides onto Terminal Alkynes

    James McNulty;Kunal Keskar

  • Novel Class of Tertiary Phosphine Ligands Based on a Phospha-adamantane Framework and Use in the Suzuki Cross-Coupling Reactions of Aryl Halides under Mild Conditions

    George Adjabeng;Tim Brenstrum;Jeffrey Wilson;Christopher Frampton

  • Structure-activity studies on the lycorine pharmacophore: A potent inducer of apoptosis in human leukemia cells.

    James McNulty;Jerald J. Nair;Jaume Bastida;Siyaram Pandey

  • Antineoplastic agents. 362. Isolation and X-ray crystal structure of dibromophakellstatin from the Indian ocean sponge Phakellia mauritiana.

    George R. Pettit;James McNulty;Delbert L. Herald;Dennis L. Doubek

  • Phosphaadamantanes as Ligands for Palladium Catalyzed Cross-Coupling Chemistry: Library Synthesis, Characterization, and Screening in the Suzuki Coupling of Alkyl Halides and Tosylates Containing β-Hydrogens with Boronic Acids and Alkylboranes

    Tim Brenstrum;David A. Gerristma;George M. Adjabeng;Christopher S. Frampton

  • Highly Stereoselective and General Synthesis of (E)-Stilbenes and Alkenes by Means of an Aqueous Wittig Reaction

    James McNulty;Priyabrata Das

  • Suzuki cross-coupling reactions of aryl halides in phosphonium salt ionic liquid under mild conditions

    James McNulty;Alfredo Capretta;Jeff Wilson;Jeff Dyck

  • Efficient Carbonylation Reactions in Phosphonium Salt Ionic Liquids: Anionic Effects

    James McNulty;Jerald J. Nair;Al Robertson

  • A mild esterification process in phosphonium salt ionic liquid

    James McNulty;Sreedhar Cheekoori;Jerald J. Nair;Vladimir Larichev

  • Microwave‐Assisted, Aqueous Wittig Reactions: Organic‐Solvent‐ and Protecting‐Group‐Free Chemoselective Synthesis of Functionalized Alkenes

    James McNulty;Priyabrata Das;David McLeod

  • Heck reactions of aryl halides in phosphonium salt ionic liquids: library screening and applications

    David A. Gerritsma;Al Robertson;James McNulty;Alfredo Capretta

  • Scope and Mechanistic Insights into the Use of Tetradecyl(trihexyl)phosphonium Bistriflimide: A Remarkably Selective Ionic Liquid Solvent for Substitution Reactions

    James McNulty;Jerald J. Nair;Sreedhar Cheekoori;Vladimir Larichev

  • Studies directed towards the refinement of the pancratistatin cytotoxic pharmacophore.

    James McNulty;Justin Mao;Romelo Gibe;Ruowei Mo

  • Pancratistatin Selectively Targets Cancer Cell Mitochondria and Reduces Growth of Human Colon Tumor Xenografts

    Carly Griffin;Aditya Karnik;James McNulty;Siyaram Pandey

  • A synthesis of 3-deoxydihydrolycoricidine: refinement of a structurally minimum pancratistatin pharmacophore.

    James McNulty;Vladimir Larichev;Siyaram Pandey

Frequent Co-Authors

Robert H. Yolken
Robert H. Yolken Johns Hopkins University
Vishwajit L. Nimgaonkar
Vishwajit L. Nimgaonkar University of Pittsburgh
Jaume Bastida
Jaume Bastida University of Barcelona
Paul R. Kinchington
Paul R. Kinchington University of Pittsburgh
Tomas Hudlicky
Tomas Hudlicky Brock University
Gerard D. Wright
Gerard D. Wright McMaster University
George R. Pettit
George R. Pettit Arizona State University
John D. Brennan
John D. Brennan McMaster University
Michael R. Boyd
Michael R. Boyd University of South Alabama
Louis F. J. Piper
Louis F. J. Piper University of Warwick

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