What is he best known for?
The fields of study he is best known for:
His scientific interests lie mostly in Nuclear transport, Nuclear localization sequence, Importin, Cell biology and Biochemistry.
His Nuclear transport research is multidisciplinary, incorporating perspectives in Molecular biology, Nuclear pore and Virology.
His Nuclear localization sequence study incorporates themes from Nuclear protein, Transcription factor and Fusion protein.
David A. Jans has included themes like Parathyroid hormone-related protein, Nucleoporin, Beta Karyopherins, Integrase and Ran in his Importin study.
His Cell biology research is multidisciplinary, incorporating elements of Perforin, Granzyme and Granzyme B.
His research in Biochemistry tackles topics such as Biophysics which are related to areas like Cell culture.
His most cited work include:
- The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro. (719 citations)
- Nuclear targeting signal recognition: a key control point in nuclear transport? (487 citations)
- Towards safe, non-viral therapeutic gene expression in humans (475 citations)
What are the main themes of his work throughout his whole career to date?
Nuclear transport, Cell biology, Importin, Nuclear localization sequence and Molecular biology are his primary areas of study.
His Nuclear transport study combines topics from a wide range of disciplines, such as Nuclear export signal, Nuclear protein and NLS.
The various areas that David A. Jans examines in his Cell biology study include Genetics and Transcription factor.
His Importin research is multidisciplinary, relying on both Beta Karyopherins, Virology, Dengue virus, Ran and Importin-alpha.
His study in Nuclear localization sequence is interdisciplinary in nature, drawing from both Green fluorescent protein, Fusion protein, Phosphorylation, Subcellular localization and Binding site.
His studies in Molecular biology integrate themes in fields like Cell culture, Protein kinase A and Protein subunit, Gene, Mutant.
He most often published in these fields:
- Nuclear transport (56.36%)
- Cell biology (52.73%)
- Importin (40.91%)
What were the highlights of his more recent work (between 2014-2021)?
- Virology (18.18%)
- Nuclear transport (56.36%)
- Importin (40.91%)
In recent papers he was focusing on the following fields of study:
David A. Jans mainly focuses on Virology, Nuclear transport, Importin, Cell biology and Virus.
The concepts of his Nuclear transport study are interwoven with issues in Nuclear export signal, Molecular biology, Nuclear localization sequence and Transporter.
His research on Nuclear localization sequence concerns the broader Biochemistry.
In his research on the topic of Importin, Beta Karyopherins is strongly related with Alpha Karyopherins.
Within one scientific family, David A. Jans focuses on topics pertaining to Nuclear protein under Cell biology, and may sometimes address concerns connected to Interactome.
David A. Jans studied Virus and Mitochondrion that intersect with Reactive oxygen species.
Between 2014 and 2021, his most popular works were:
- The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro. (719 citations)
- The broad spectrum antiviral ivermectin targets the host nuclear transport importin α/β1 heterodimer (104 citations)
- Influenza A viruses escape from MxA restriction at the expense of efficient nuclear vRNP import (82 citations)
In his most recent research, the most cited papers focused on:
David A. Jans spends much of his time researching Virology, Nuclear transport, Importin, Cell biology and Viral replication.
His work in the fields of Virology, such as Virus and 2019-20 coronavirus outbreak, intersects with other areas such as Ivermectin and Initiation factor.
His Virus study combines topics in areas such as Inflammation and Outbreak.
His Nuclear transport study combines topics in areas such as Nuclear export signal, RNA, Nuclear localization sequence and Dengue virus.
His Importin study incorporates themes from Transport protein, Receptor and Transporter.
His research on Cell biology frequently connects to adjacent areas such as Spermatogenesis.
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