World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
60
Citations
20437
World Ranking
11711
National Ranking
834

Overview

Falk Fahrenholz is a researcher affiliated with Johannes Gutenberg University of Mainz in Germany. Their work primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology. They have contributed to multiple subfields including Oncology, Immunology and Allergy, Cell Biology, and Molecular Biology.

Their research covers several interconnected topics:

  • HER2/EGFR in Cancer Research
  • Cell Adhesion Molecules Research
  • Cellular Mechanics and Interactions
  • Peptidase Inhibition and Analysis
  • Signaling Pathways in Disease

Fahrenholz has published articles in venues such as UNC Libraries. A noted recent paper from 2020 is titled "Transmembrane collagen XVII, an epithelial adhesion protein, is shed from the cell surface by ADAMs", published by UNC Libraries.

Frequent co-authors in Fahrenholz's scientific work include Claus Franzke, Kaisa Tasanen, Heike Schäcke, Zhongjun Zhou, and Karl Tryggvason. Collaboration with these researchers reflects engagement in studies related to cellular adhesion and molecular mechanisms in disease contexts.

While the available data does not record any published books or awards, Fahrenholz's contributions are focused on detailed mechanistic studies in cell adhesion and cancer-related signaling pathways, an area drawing from both molecular biology and oncology perspectives.

Best Publications

  • The Oxytocin Receptor System: Structure, Function, and Regulation

    Gerald Gimpl;Falk Fahrenholz

  • Constitutive and regulated α-secretase cleavage of Alzheimer’s amyloid precursor protein by a disintegrin metalloprotease

    Sven Lammich;Elzbieta Kojro;Rolf Postina;Sandra Gilbert

  • Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the α-secretase ADAM 10

    Elzbieta Kojro;Gerald Gimpl;Sven Lammich;Winfried März

  • A disintegrin-metalloproteinase prevents amyloid plaque formation and hippocampal defects in an Alzheimer disease mouse model.

    Rolf Postina;Anja Schroeder;Ilse Dewachter;Juergen Bohl

  • The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion.

    Christian Hundhausen;Dominika Misztela;Theo A. Berkhout;Neil Broadway

  • Cholesterol binds to synaptophysin and is required for biogenesis of synaptic vesicles

    Christoph Thiele;Christoph Thiele;Matthew J. Hannah;Matthew J. Hannah;Matthew J. Hannah;Falk Fahrenholz;Wieland B. Huttner;Wieland B. Huttner

  • Alteration of the Myometrial Plasma Membrane Cholesterol Content with .beta.-Cyclodextrin Modulates the Binding Affinity of the Oxytocin Receptor

    Uwe Klein;Gerald Gimpl;Falk Fahrenholz

  • Cholesterol as modulator of receptor function.

    Gerald Gimpl;Katja Burger;Falk Fahrenholz

  • Ectodomain shedding of L1 adhesion molecule promotes cell migration by autocrine binding to integrins

    Sabine Mechtersheimer;Paul Gutwein;Nancy Agmon-Levin;Alexander Stoeck

  • Regulation of receptor function by cholesterol.

    K. Burger;G. Gimpl;F. Fahrenholz

  • Receptor for Advanced Glycation End Products Is Subjected to Protein Ectodomain Shedding by Metalloproteinases

    Ling Zhang;Monika Bukulin;Elzbieta Kojro;Annette Roth

  • Regulation of the α -secretase ADAM10 by its prodomain and proprotein convertases

    Andreas Anders;Sandra Gilbert;Wolfgang Garten;Rolf Postina

  • The non-amyloidogenic pathway: structure and function of alpha-secretases.

    Elżbieta Kojro;Falk Fahrenholz

  • Up-regulation of the alpha-secretase ADAM10 by retinoic acid receptors and acitretin.

    Frank Tippmann;Jana Hundt;Anja Schneider;Kristina Endres

  • Transmembrane collagen XVII, an epithelial adhesion protein, is shed from the cell surface by ADAMs.

    Claus‐Werner Franzke;Kaisa Tasanen;Heike Schäcke;Zhongjun Zhou

  • Expression of the human oxytocin receptor in baculovirus-infected insect cells: high-affinity binding is induced by a cholesterol-cyclodextrin complex.

    Gerald Gimpl;Uwe Klein;Helmut Reiländer;Falk Fahrenholz

  • Molecular cloning of a new bombesin receptor subtype expressed in uterus during pregnancy

    Valentin Gorbulev;Aida Akhundova;Hubert Büchner;Falk Fahrenholz

  • The quinone-reactive Ni/Fe-hydrogenase of Wolinella succinogenes.

    Felix Dross;Viktor Geisler;Ruth Lenger;Friedbert Theis

  • Separate Agonist and Peptide Antagonist Binding Sites of the Oxytocin Receptor Defined by Their Transfer into the V2 Vasopressin Receptor

    Rolf Postina;Elzbieta Kojro;Falk Fahrenholz

  • Neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP) slows down Alzheimer’s disease-like pathology in amyloid precursor protein-transgenic mice

    Dorothea Rat;Ulrich Schmitt;Frank Tippmann;Ilse Dewachter

Frequent Co-Authors

David A. Jans
David A. Jans Monash University
Christoph Thiele
Christoph Thiele University of Bonn
Christian Haass
Christian Haass Ludwig-Maximilians-Universität München
Paul Saftig
Paul Saftig Kiel University
Achim Kröger
Achim Kröger Goethe University Frankfurt
Theodor Wieland
Theodor Wieland Max Planck Society
Andreas Fellgiebel
Andreas Fellgiebel Johannes Gutenberg University of Mainz
Wieland B. Huttner
Wieland B. Huttner Max Planck Society
Vance Lemmon
Vance Lemmon University of Miami
Kazuo Yamamoto
Kazuo Yamamoto University of Tokyo

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Best Scientists Citing Falk Fahrenholz