D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 55 Citations 17,471 125 World Ranking 7544 National Ranking 574

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Amino acid

Falk Fahrenholz focuses on Receptor, Biochemistry, Internal medicine, Endocrinology and Cell biology. His Receptor research is multidisciplinary, incorporating perspectives in Vasopressin and Cholesterol. His Biochemistry study combines topics from a wide range of disciplines, such as Alpha secretase and Amyloid precursor protein.

The study incorporates disciplines such as Retinoic acid receptor, Retinoic acid receptor beta, Retinoid X receptor gamma and Retinoid X receptor beta in addition to Internal medicine. His research in Endocrinology intersects with topics in Synaptic plasticity, Alpha, Retinoid X receptor alpha and Retinoic acid receptor alpha. His work in the fields of Oxytocin receptor binding overlaps with other areas such as Posterior pituitary.

His most cited work include:

  • The Oxytocin Receptor System: Structure, Function, and Regulation (2169 citations)
  • Constitutive and regulated α-secretase cleavage of Alzheimer’s amyloid precursor protein by a disintegrin metalloprotease (997 citations)
  • Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the α-secretase ADAM 10 (704 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Biochemistry, Receptor, Vasopressin, Internal medicine and Endocrinology. His studies in Biochemistry integrate themes in fields like Molecular biology and Amyloid precursor protein. His Receptor study combines topics in areas such as Biophysics and Binding site.

His work deals with themes such as Neuropeptide and Cell biology, which intersect with Endocrinology. The Cell biology study combines topics in areas such as Enzyme-linked receptor and Alpha secretase. In his research on the topic of Oxytocin receptor, Membrane is strongly related with Cholesterol.

He most often published in these fields:

  • Biochemistry (36.93%)
  • Receptor (34.09%)
  • Vasopressin (29.55%)

What were the highlights of his more recent work (between 2005-2014)?

  • ADAM10 (15.91%)
  • Amyloid precursor protein (14.77%)
  • Cell biology (15.34%)

In recent papers he was focusing on the following fields of study:

Falk Fahrenholz mainly investigates ADAM10, Amyloid precursor protein, Cell biology, Alpha secretase and Cancer research. The various areas that he examines in his Amyloid precursor protein study include Molecular biology, Genetically modified mouse and Downregulation and upregulation. His research integrates issues of Transcriptional regulation and Binding site in his study of Cell biology.

His Alpha secretase study contributes to a more complete understanding of Internal medicine. His biological study spans a wide range of topics, including Retinoic acid receptor alpha and Drug. His work on Receptor, Vasotocin and Agonist as part of general Biochemistry study is frequently linked to Water flow, therefore connecting diverse disciplines of science.

Between 2005 and 2014, his most popular works were:

  • Receptor for Advanced Glycation End Products Is Subjected to Protein Ectodomain Shedding by Metalloproteinases (212 citations)
  • Up-regulation of the α-secretase ADAM10 by retinoic acid receptors and acitretin (160 citations)
  • ADAM-10 over-expression increases cortical synaptogenesis. (106 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Amino acid

His primary scientific interests are in Amyloid precursor protein, Internal medicine, ADAM10, Alpha secretase and Endocrinology. He studied Amyloid precursor protein and G protein-coupled receptor that intersect with Transcription factor, Extracellular, ASK1, MAP kinase kinase kinase and Neuropeptide. His work on Alzheimer's disease and Prospective cohort study as part of general Internal medicine research is often related to Acitretin and Placebo, thus linking different fields of science.

His ADAM10 research incorporates themes from Protein biotinylation, Downregulation and upregulation, Neuroprotection, Cell biology and Retinoic acid. His research ties Receptor and Alpha secretase together. His Endocrinology research is multidisciplinary, relying on both Retinoic acid receptor, Retinoid X receptor gamma, Neurotrophin and Alpha.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The Oxytocin Receptor System: Structure, Function, and Regulation

Gerald Gimpl;Falk Fahrenholz.
Physiological Reviews (2001)

3578 Citations

Constitutive and regulated α-secretase cleavage of Alzheimer’s amyloid precursor protein by a disintegrin metalloprotease

Sven Lammich;Elzbieta Kojro;Rolf Postina;Sandra Gilbert.
Proceedings of the National Academy of Sciences of the United States of America (1999)

1557 Citations

Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the α-secretase ADAM 10

Elzbieta Kojro;Gerald Gimpl;Sven Lammich;Winfried März.
Proceedings of the National Academy of Sciences of the United States of America (2001)

1102 Citations

A disintegrin-metalloproteinase prevents amyloid plaque formation and hippocampal defects in an Alzheimer disease mouse model.

Rolf Postina;Anja Schroeder;Ilse Dewachter;Juergen Bohl.
Journal of Clinical Investigation (2004)

757 Citations

The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion.

Christian Hundhausen;Dominika Misztela;Theo A. Berkhout;Neil Broadway.
Blood (2003)

694 Citations

Alteration of the Myometrial Plasma Membrane Cholesterol Content with .beta.-Cyclodextrin Modulates the Binding Affinity of the Oxytocin Receptor

Uwe Klein;Gerald Gimpl;Falk Fahrenholz.
Biochemistry (1995)

670 Citations

Cholesterol binds to synaptophysin and is required for biogenesis of synaptic vesicles

Christoph Thiele;Christoph Thiele;Matthew J. Hannah;Matthew J. Hannah;Matthew J. Hannah;Falk Fahrenholz;Wieland B. Huttner;Wieland B. Huttner.
Nature Cell Biology (2000)

623 Citations

Cholesterol as modulator of receptor function.

Gerald Gimpl;Katja Burger;Falk Fahrenholz.
Biochemistry (1997)

600 Citations

Ectodomain shedding of L1 adhesion molecule promotes cell migration by autocrine binding to integrins

Sabine Mechtersheimer;Paul Gutwein;Nancy Agmon-Levin;Alexander Stoeck.
Journal of Cell Biology (2001)

460 Citations

Regulation of receptor function by cholesterol.

K. Burger;G. Gimpl;F. Fahrenholz.
Cellular and Molecular Life Sciences (2000)

404 Citations

If you think any of the details on this page are incorrect, let us know.

Contact us

Best Scientists Citing Falk Fahrenholz

Amitabha Chattopadhyay

Amitabha Chattopadhyay

Centre for Cellular and Molecular Biology

Publications: 75

Paul Saftig

Paul Saftig

Kiel University

Publications: 56

Andreas Ludwig

Andreas Ludwig

RWTH Aachen University

Publications: 56

Werner E. G. Müller

Werner E. G. Müller

Johannes Gutenberg University of Mainz

Publications: 55

Stefan Rose-John

Stefan Rose-John

Kiel University

Publications: 48

Peter Altevogt

Peter Altevogt

German Cancer Research Center

Publications: 42

Stefan F. Lichtenthaler

Stefan F. Lichtenthaler

German Center for Neurodegenerative Diseases

Publications: 41

Isabel M. Müller

Isabel M. Müller

Johannes Gutenberg University of Mainz

Publications: 40

Bart De Strooper

Bart De Strooper

KU Leuven

Publications: 39

Carl P. Blobel

Carl P. Blobel

Cornell University

Publications: 38

Laurence J. Miller

Laurence J. Miller

Mayo Clinic

Publications: 38

Leena Bruckner-Tuderman

Leena Bruckner-Tuderman

University of Freiburg

Publications: 37

Tobias Hartmann

Tobias Hartmann

Saarland University

Publications: 32

Heinz C. Schröder

Heinz C. Schröder

Johannes Gutenberg University of Mainz

Publications: 32

Melitta Schachner

Melitta Schachner

Rutgers, The State University of New Jersey

Publications: 31

Monica Di Luca

Monica Di Luca

University of Milan

Publications: 29

Trending Scientists

Philipp Slusallek

Philipp Slusallek

Saarland University

Christian von Hirschhausen

Christian von Hirschhausen

German Institute for Economic Research

Rolf Schneider

Rolf Schneider

University of Freiburg

Albrecht Schmidt

Albrecht Schmidt

Ludwig-Maximilians-Universität München

Jiang Li

Jiang Li

Microsoft (United States)

N. Sukumar

N. Sukumar

University of California, Davis

Johan Stenflo

Johan Stenflo

Lund University

Vy M. Dong

Vy M. Dong

University of California, Irvine

Chun-Yu Liu

Chun-Yu Liu

Boston University

Erin G. Schuetz

Erin G. Schuetz

St. Jude Children's Research Hospital

Paul B. McCray

Paul B. McCray

University of Iowa

Sho Yamasaki

Sho Yamasaki

Osaka University

Carlos Crespo

Carlos Crespo

University of Valencia

Kenneth I. Forster

Kenneth I. Forster

University of Arizona

Ivan W. Miller

Ivan W. Miller

Brown University

David L. Kaplan

David L. Kaplan

University of Wisconsin–Milwaukee

Something went wrong. Please try again later.