Falk Fahrenholz focuses on Receptor, Biochemistry, Internal medicine, Endocrinology and Cell biology. His Receptor research is multidisciplinary, incorporating perspectives in Vasopressin and Cholesterol. His Biochemistry study combines topics from a wide range of disciplines, such as Alpha secretase and Amyloid precursor protein.
The study incorporates disciplines such as Retinoic acid receptor, Retinoic acid receptor beta, Retinoid X receptor gamma and Retinoid X receptor beta in addition to Internal medicine. His research in Endocrinology intersects with topics in Synaptic plasticity, Alpha, Retinoid X receptor alpha and Retinoic acid receptor alpha. His work in the fields of Oxytocin receptor binding overlaps with other areas such as Posterior pituitary.
His main research concerns Biochemistry, Receptor, Vasopressin, Internal medicine and Endocrinology. His studies in Biochemistry integrate themes in fields like Molecular biology and Amyloid precursor protein. His Receptor study combines topics in areas such as Biophysics and Binding site.
His work deals with themes such as Neuropeptide and Cell biology, which intersect with Endocrinology. The Cell biology study combines topics in areas such as Enzyme-linked receptor and Alpha secretase. In his research on the topic of Oxytocin receptor, Membrane is strongly related with Cholesterol.
Falk Fahrenholz mainly investigates ADAM10, Amyloid precursor protein, Cell biology, Alpha secretase and Cancer research. The various areas that he examines in his Amyloid precursor protein study include Molecular biology, Genetically modified mouse and Downregulation and upregulation. His research integrates issues of Transcriptional regulation and Binding site in his study of Cell biology.
His Alpha secretase study contributes to a more complete understanding of Internal medicine. His biological study spans a wide range of topics, including Retinoic acid receptor alpha and Drug. His work on Receptor, Vasotocin and Agonist as part of general Biochemistry study is frequently linked to Water flow, therefore connecting diverse disciplines of science.
His primary scientific interests are in Amyloid precursor protein, Internal medicine, ADAM10, Alpha secretase and Endocrinology. He studied Amyloid precursor protein and G protein-coupled receptor that intersect with Transcription factor, Extracellular, ASK1, MAP kinase kinase kinase and Neuropeptide. His work on Alzheimer's disease and Prospective cohort study as part of general Internal medicine research is often related to Acitretin and Placebo, thus linking different fields of science.
His ADAM10 research incorporates themes from Protein biotinylation, Downregulation and upregulation, Neuroprotection, Cell biology and Retinoic acid. His research ties Receptor and Alpha secretase together. His Endocrinology research is multidisciplinary, relying on both Retinoic acid receptor, Retinoid X receptor gamma, Neurotrophin and Alpha.
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The Oxytocin Receptor System: Structure, Function, and Regulation
Gerald Gimpl;Falk Fahrenholz.
Physiological Reviews (2001)
Constitutive and regulated α-secretase cleavage of Alzheimer’s amyloid precursor protein by a disintegrin metalloprotease
Sven Lammich;Elzbieta Kojro;Rolf Postina;Sandra Gilbert.
Proceedings of the National Academy of Sciences of the United States of America (1999)
Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the α-secretase ADAM 10
Elzbieta Kojro;Gerald Gimpl;Sven Lammich;Winfried März.
Proceedings of the National Academy of Sciences of the United States of America (2001)
A disintegrin-metalloproteinase prevents amyloid plaque formation and hippocampal defects in an Alzheimer disease mouse model.
Rolf Postina;Anja Schroeder;Ilse Dewachter;Juergen Bohl.
Journal of Clinical Investigation (2004)
The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion.
Christian Hundhausen;Dominika Misztela;Theo A. Berkhout;Neil Broadway.
Alteration of the Myometrial Plasma Membrane Cholesterol Content with .beta.-Cyclodextrin Modulates the Binding Affinity of the Oxytocin Receptor
Uwe Klein;Gerald Gimpl;Falk Fahrenholz.
Cholesterol binds to synaptophysin and is required for biogenesis of synaptic vesicles
Christoph Thiele;Christoph Thiele;Matthew J. Hannah;Matthew J. Hannah;Matthew J. Hannah;Falk Fahrenholz;Wieland B. Huttner;Wieland B. Huttner.
Nature Cell Biology (2000)
Cholesterol as modulator of receptor function.
Gerald Gimpl;Katja Burger;Falk Fahrenholz.
Ectodomain shedding of L1 adhesion molecule promotes cell migration by autocrine binding to integrins
Sabine Mechtersheimer;Paul Gutwein;Nancy Agmon-Levin;Alexander Stoeck.
Journal of Cell Biology (2001)
Regulation of receptor function by cholesterol.
K. Burger;G. Gimpl;F. Fahrenholz.
Cellular and Molecular Life Sciences (2000)
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