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Christoph Thiele

Christoph Thiele

D-Index & Metrics

Biology and Biochemistry

D-Index
64
Citations
17451
World Ranking
9535
National Ranking
693

Overview

Christoph Thiele is affiliated with the University of Bonn in Germany and has contributed extensively to research in biochemistry, genetics, molecular biology, and medicine. Their scientific work spans multiple subfields including molecular biology, immunology, surgery, physiology, and epidemiology.

The main topics Christoph Thiele has focused on include:

  • Lipid metabolism and biosynthesis
  • Adipose tissue and metabolism
  • Metabolomics and mass spectrometry studies
  • Sphingolipid metabolism and signaling
  • Pancreatic function and diabetes
  • Immune cells in cancer
  • Adipokines, inflammation, and metabolic diseases

Frequently published venues for their work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Immunity
  • Scientific Reports
  • Journal of Lipid Research
  • Molecular Metabolism

Christoph Thiele has collaborated regularly with several coauthors, most frequently with:

  • Klaus Wunderling
  • Jelena Zurkovic
  • Lars Kuerschner
  • Mohamed Yaghmour
  • Jan Hasenauer

Among recent papers, notable publications include:

  • Lipid-Droplet Formation Drives Pathogenic Group 2 Innate Lymphoid Cells in Airway Inflammation, 2020, Immunity
  • Triglyceride cycling enables modification of stored fatty acids, 2023, Nature Metabolism
  • Kupffer Cells Sense Free Fatty Acids and Regulate Hepatic Lipid Metabolism in High-Fat Diet and Inflammation, 2020, Cells
  • 1-Deoxysphingolipids cause autophagosome and lysosome accumulation and trigger NLRP3 inflammasome activation, 2020, Autophagy
  • Enhanced lipid biosynthesis in human tumor-induced macrophages contributes to their protumoral characteristics, 2020, Journal for ImmunoTherapy of Cancer

Best Publications

  • Amyloidogenic processing of the Alzheimer β-amyloid precursor protein depends on lipid rafts

    Robert Ehehalt;Patrick Keller;Christian Haass;Christoph Thiele

  • Lipoprotein particles are required for Hedgehog and Wingless signalling

    Daniela Panáková;Hein Sprong;Eric Marois;Christoph Thiele

  • SNAREs are concentrated in cholesterol-dependent clusters that define docking and fusion sites for exocytosis

    Thorsten Lang;Dieter Bruns;Dirk Wenzel;Dietmar Riedel

  • Metabolic activation of intrahepatic CD8+ T cells and NKT cells causes nonalcoholic steatohepatitis and liver cancer via cross-talk with hepatocytes

    Monika Julia Wolf;Arlind Adili;Kira Piotrowitz;Zeinab Abdullah

  • Endophilin I mediates synaptic vesicle formation by transfer of arachidonate to lysophosphatidic acid

    Anne Schmidt;Anne Schmidt;Michael Wolde;Christoph Thiele;Christoph Thiele;Werner Fest

  • Cholesterol binds to synaptophysin and is required for biogenesis of synaptic vesicles

    Christoph Thiele;Christoph Thiele;Matthew J. Hannah;Matthew J. Hannah;Matthew J. Hannah;Falk Fahrenholz;Wieland B. Huttner;Wieland B. Huttner

  • Induction of the nuclear receptor PPAR-γ by the cytokine GM-CSF is critical for the differentiation of fetal monocytes into alveolar macrophages

    Christoph Schneider;Samuel P Nobs;Michael Kurrer;Hubert Rehrauer

  • Photo-leucine and photo-methionine allow identification of protein-protein interactions in living cells

    Monika Suchanek;Anna Radzikowska;Christoph Thiele

  • ATP-binding Cassette Transporter A1 (ABCA1) Functions as a Cholesterol Efflux Regulatory Protein *

    Nan Wang;David L. Silver;Christoph Thiele;Alan R. Tall

  • Imaging of lipid biosynthesis: how a neutral lipid enters lipid droplets.

    Lars Kuerschner;Christine Moessinger;Christoph Thiele

  • Automated identification and quantification of glycerophospholipid molecular species by multiple precursor ion scanning.

    Christer S. Ejsing;Eva Duchoslav;Julio Sampaio;Kai Simons

  • Molecular recognition of a single sphingolipid species by a protein’s transmembrane domain

    F.-Xabier Contreras;Andreas M. Ernst;Per Haberkant;Per Haberkant;Patrik Björkholm;Patrik Björkholm

  • Cell biology of lipid droplets.

    Christoph Thiele;Johanna Spandl

  • Seipin regulates ER-lipid droplet contacts and cargo delivery.

    Veijo T Salo;Veijo T Salo;Ilya Belevich;Shiqian Li;Shiqian Li;Leena Karhinen

  • Assembly of myelin by association of proteolipid protein with cholesterol- and galactosylceramide-rich membrane domains.

    Mikael Simons;Eva-Maria Krämer;Christoph Thiele;Wilhelm Stoffel

  • Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels.

    Tobias B. Huber;Bernhard Schermer;Roman Ulrich Müller;Martin Höhne

  • A physical and functional link between cholesterol and tetraspanins

    Stéphanie Charrin;Serge Manié;Christoph Thiele;Martine Billard

  • Live cell multicolor imaging of lipid droplets with a new dye, LD540.

    Johanna Spandl;Daniel J. White;Jan Peychl;Christoph Thiele

  • Distribution and transport of cholesterol in Caenorhabditis elegans.

    Vitali Matyash;Christian Geier;Annemarie Henske;Sushmita Mukherjee

  • Cholesterol-induced caveolin targeting to lipid droplets in adipocytes: a role for caveolar endocytosis.

    Soazig Le Lay;Eric Hajduch;Margaret R. Lindsay;Xavier Le Lièpvre

Frequent Co-Authors

Wieland B. Huttner
Wieland B. Huttner Max Planck Society
Andrej Shevchenko
Andrej Shevchenko Max Planck Society
Denis Corbeil
Denis Corbeil TU Dresden
Vesa M. Olkkonen
Vesa M. Olkkonen University of Helsinki
Falk Fahrenholz
Falk Fahrenholz Johannes Gutenberg University of Mainz
Teymuras V. Kurzchalia
Teymuras V. Kurzchalia Max Planck Society
Hein Sprong
Hein Sprong Wageningen University & Research
Kai Simons
Kai Simons Lipotype
Maria M. Mota
Maria M. Mota University of Lisbon

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