2026 John T.R. Isaac: Neuroscience Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Neuroscience	63	3367	3079	1563	1412	110	16393

Discipline name

D-Index

World Ranking

Current World Ranking

National Ranking

Current National Ranking

Publications

Citations

Neuroscience

3367

3079

1563

1412

110

16393

Overview

John T.R. Isaac is affiliated with Johnson & Johnson in the United States. Their research primarily lies within the field of Medicine, with a specific focus on Surgery, Hepatology, and Oncology. Additional subfields of study include Pulmonary and Respiratory Medicine and Cancer Research.

The scientist's work spans several main topics including:

Cholangiocarcinoma and Gallbladder Cancer Studies
Hepatocellular Carcinoma Treatment and Prognosis
Liver Disease and Transplantation
Organ Transplantation Techniques and Outcomes
Pancreatic and Hepatic Oncology Research
Cancer Genomics and Diagnostics
Liver Disease Diagnosis and Treatment

John T.R. Isaac has contributed to numerous publications, frequently appearing in the following venues:

HPB
Annals of Surgical Oncology
bioRxiv (Cold Spring Harbor Laboratory)
Transplantation
Journal of Neuroscience

Selected recent papers by the scientist include:

Surgery for Bismuth-Corlette Type 4 Perihilar Cholangiocarcinoma: Results from a Western Multicenter Collaborative Group, 2021, Annals of Surgical Oncology
Circuit-Specific Plasticity of Callosal Inputs Underlies Cortical Takeover, 2020, Journal of Neuroscience
The effects of resection margin and KRAS status on outcomes after resection of colorectal liver metastases, 2020, HPB
The role of down staging treatment in the management of locally advanced intrahepatic cholangiocarcinoma: Review of literature and pooled analysis, 2020, Annals of Hepato-Biliary-Pancreatic Surgery
Outcome after ex situ or ante situm liver resection with hypothermic perfusion and auto-transplantation: A single-centre experience in adult and paediatric patients, 2020, Journal of Surgical Oncology

Frequent coauthors collaborating with John T.R. Isaac include:

B. Dasari
Ravi Marudanayagam
N. Chatzizacharias
Paolo Muiesan
Robert P. Sutcliffe

Best Publications

Evidence for silent synapses: Implications for the expression of LTP

John T.R. Isaac;Roger A. Nicoll;Robert C. Malenka

1486
Citations
Receptor trafficking and synaptic plasticity

Graham L. Collingridge;Graham L. Collingridge;John T. R. Isaac;John T. R. Isaac;Yu Tian Wang

1301
Citations
The Role of the GluR2 Subunit in AMPA Receptor Function and Synaptic Plasticity

John T.R. Isaac;Michael C. Ashby;Chris J. McBain

969
Citations
LTP inhibits LTD in the hippocampus via regulation of GSK3beta.

Stéphane Peineau;Changiz Taghibiglou;Clarrisa Bradley;Tak Pan Wong

816
Citations
NSF Binding to GluR2 Regulates Synaptic Transmission

Atsushi Nishimune;John T.R Isaac;Elek Molnar;Jacques Noel

801
Citations
Modulation of AMPA receptor unitary conductance by synaptic activity

Tim A. Benke;Tim A. Benke;Andreas Lüthi;Andreas Lüthi;John T. R. Isaac;Graham L. Collingridge

722
Citations
Transient incorporation of native GluR2-lacking AMPA receptors during hippocampal long-term potentiation

Karen Plant;Kenneth A Pelkey;Zuner A Bortolotto;Daiju Morita;Daiju Morita

654
Citations
Silent Synapses during Development of Thalamocortical Inputs

John T.R. Isaac;Michael C. Crair;Roger A. Nicoll;Robert C. Malenka

633
Citations
PDZ Proteins Interacting with C-Terminal GluR2/3 Are Involved in a PKC-Dependent Regulation of AMPA Receptors at Hippocampal Synapses

Michael I. Daw;Ramesh Chittajallu;Zuner A. Bortolotto;Kumlesh K. Dev

419
Citations
Hippocampal LTD expression involves a pool of AMPARs regulated by the NSF-GluR2 interaction.

Andreas Lüthi;Ramesh Chittajallu;Fabrice Duprat;Mary J Palmer

361
Citations
Developmental and activity- dependent regulation of kainate receptors at thalamocortical synapses

Fleur L. Kidd;John T. R. Isaac

326
Citations
Casein Kinase 2 Regulates the NR2 Subunit Composition of Synaptic NMDA Receptors

Antonio Sanz-Clemente;Jose A. Matta;John T.R. Isaac;Katherine W. Roche

281
Citations
Rapid and Differential Regulation of AMPA and Kainate Receptors at Hippocampal Mossy Fibre Synapses by PICK1 and GRIP

Hélène Hirbec;Joanna C Francis;Sari E Lauri;Steven P Braithwaite

269
Citations
Olig1 and Olig2 triplication causes developmental brain defects in Down syndrome

Lina Chakrabarti;Tyler K Best;Nathan P Cramer;Rosalind S E Carney

264
Citations
A critical role of a facilitatory presynaptic kainate receptor in mossy fiber LTP.

Sari E Lauri;Zuner A Bortolotto;David Bleakman;Paul L Ornstein

255
Citations
A Role for Ca2+ Stores in Kainate Receptor-Dependent Synaptic Facilitation and LTP at Mossy Fiber Synapses in the Hippocampus

Sari E Lauri;Zuner A Bortolotto;Robert Nistico;David Bleakman

241
Citations
Regulation of synaptic strength and AMPA receptor subunit composition by PICK1

Akira Terashima;Lucy Cotton;Kumlesh K. Dev;Guido Meyer

229
Citations
Long-Term Depression at Thalamocortical Synapses in Developing Rat Somatosensory Cortex

Daniel E Feldman;Roger A Nicoll;Robert C Malenka;John T.R Isaac

211
Citations
mGluR5 and NMDA Receptors Drive the Experience- and Activity-Dependent NMDA Receptor NR2B to NR2A Subunit Switch

Jose A. Matta;Michael C. Ashby;Antonio Sanz-Clemente;Katherine W. Roche

211
Citations
An Essential Role for PICK1 in NMDA Receptor-Dependent Bidirectional Synaptic Plasticity

Akira Terashima;Kenneth A. Pelkey;Jong Cheol Rah;Young Ho Suh

209
Citations