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D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
14725
World Ranking
10733
National Ranking
4659

Overview

Katherine W. Roche is affiliated with the National Institutes of Health in the United States and focuses their research primarily in the fields of Biochemistry, Genetics and Molecular Biology, as well as Neuroscience. Their work encompasses a range of subfields including Molecular Biology, Cellular and Molecular Neuroscience, Genetics, Cognitive Neuroscience, and Cell Biology.

The scientist's research explores several main topics, such as Neuroscience and Neuropharmacology Research, Genetics and Neurodevelopmental Disorders, Ion channel regulation and function, Autism Spectrum Disorder Research, Receptor Mechanisms and Signaling, RNA and protein synthesis mechanisms, and Cellular transport and secretion.

Frequent co-authors in their publications include Marta Vieira, Victor Anggono, Thien Nguyen, Alexander W. Lehr, and Wei Lü. These collaborations often appear in well-recognized publication venues where the scientist has multiple contributions, such as the Journal of Neuroscience, Trends in Neurosciences, Cell Reports, eNeuro, and Genetics in Medicine.

The scientist's recent papers include:

  • Regulation of NMDA glutamate receptor functions by the GluN2 subunits, 2020, Journal of Neurochemistry
  • A Cluster of Autism-Associated Variants on X-Linked NLGN4X Functionally Resemble NLGN4Y, 2020, Neuron
  • Neuroligins and Neurodevelopmental Disorders: X-Linked Genetics, 2020, Frontiers in Synaptic Neuroscience
  • Kalirin and Trio: RhoGEFs in Synaptic Transmission, Plasticity, and Complex Brain Disorders, 2020, Trends in Neurosciences
  • An Epilepsy-Associated GRIN2A Rare Variant Disrupts CaMKIIα Phosphorylation of GluN2A and NMDA Receptor Trafficking, 2020, Cell Reports

Best Publications

  • Homer: a protein that selectively binds metabotropic glutamate receptors.

    P. R. Brakeman;A. A. Lanahan;Richard O'Brien;K. Roche

  • Characterization of Multiple Phosphorylation Sites on the AMPA Receptor GluR1 Subunit

    Katherine W Roche;Richard J O'Brien;Andrew L Mammen;Jeffrey Bernhardt

  • Molecular determinants of NMDA receptor internalization.

    Katherine W. Roche;Steve Standley;Jennifer McCallum;C. Dune Ly

  • Phosphorylation of the alpha-amino-3-hydroxy-5-methylisoxazole4-propionic acid receptor GluR1 subunit by calcium/calmodulin-dependent kinase II.

    Andrew L. Mammen;Kimihiko Kameyama;Katherine W. Roche;Richard L. Huganir

  • Regulation of NMDA receptor phosphorylation by alternative splicing of the C-terminal domain.

    Whittemore G. Tingley;Katherine W. Roche;Angela K. Thompson;Richard L. Huganir

  • AP‐3: an adaptor‐like protein complex with ubiquitous expression

    Esteban C. Dell'Angelica;Hiroshi Ohno;Chean Eng Ooi;Efrat Rabinovich

  • Regulation of NMDA receptors by phosphorylation.

    Bo Shiun Chen;Katherine W. Roche

  • Diversity in NMDA Receptor Composition Many Regulators, Many Consequences

    Antonio Sanz-Clemente;Roger A. Nicoll;Katherine W. Roche

  • PDZ Domain Suppression of an ER Retention Signal in NMDA Receptor NR1 Splice Variants

    Steve Standley;Katherine W. Roche;Jennifer McCallum;Nathalie Sans

  • Subunit-Specific Regulation of NMDA Receptor Endocytosis

    Gabriela Lavezzari;Jennifer McCallum;Colleen M. Dewey;Katherine W. Roche

  • Casein Kinase 2 Regulates the NR2 Subunit Composition of Synaptic NMDA Receptors

    Antonio Sanz-Clemente;Jose A. Matta;John T.R. Isaac;Katherine W. Roche

  • Homer 1b regulates the trafficking of group I metabotropic glutamate receptors.

    Katherine W. Roche;Jian Cheng Tu;Ronald S. Petralia;Bo Xiao

  • Glutamate receptor phosphorylation and synaptic plasticity

    Katherine W. Roche;Whittemore G. Tingley;Richard L. Huganir

  • Differential binding of the AP-2 adaptor complex and PSD-95 to the C-terminus of the NMDA receptor subunit NR2B regulates surface expression

    Gabriela Lavezzari;Jennifer McCallum;Robert Lee;Katherine W Roche

  • Posttranslational regulation of AMPA receptor trafficking and function.

    Wei Lu;Katherine W Roche

  • Autonomous CaMKII Mediates Both LTP and LTD Using a Mechanism for Differential Substrate Site Selection

    Steven J. Coultrap;Ronald K. Freund;Heather O’Leary;Jennifer L. Sanderson

  • mGluR7 Is a Metaplastic Switch Controlling Bidirectional Plasticity of Feedforward Inhibition

    Kenneth A. Pelkey;Gabriela Lavezzari;Claudia Racca;Katherine W. Roche

  • mGluR5 and NMDA Receptors Drive the Experience- and Activity-Dependent NMDA Receptor NR2B to NR2A Subunit Switch

    Jose A. Matta;Michael C. Ashby;Antonio Sanz-Clemente;Katherine W. Roche

  • An Essential Role for PICK1 in NMDA Receptor-Dependent Bidirectional Synaptic Plasticity

    Akira Terashima;Kenneth A. Pelkey;Jong Cheol Rah;Young Ho Suh

  • Glutamate receptor modulation by protein phosphorylation.

    L A Raymond;W G Tingley;C D Blackstone;K W Roche

Frequent Co-Authors

Roger A. Nicoll
Roger A. Nicoll University of California, San Francisco
John T.R. Isaac
John T.R. Isaac Johnson & Johnson (United States)
Richard L. Huganir
Richard L. Huganir Johns Hopkins University School of Medicine
Paul A. Roche
Paul A. Roche National Institutes of Health
Robert J. Wenthold
Robert J. Wenthold National Institutes of Health
Kenneth A. Pelkey
Kenneth A. Pelkey National Institutes of Health
Chris J. McBain
Chris J. McBain National Institutes of Health
Ronald S. Petralia
Ronald S. Petralia National Institutes of Health
Richard J. Youle
Richard J. Youle National Institutes of Health

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