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Neuroscience

D-Index
86
Citations
30298
World Ranking
1281
National Ranking
649

Overview

Chris J. McBain is affiliated with the National Institutes of Health in the United States. Their research spans multiple domains within neuroscience and molecular biology, with a focus on cellular and molecular mechanisms. The scientist's work is primarily situated within the fields of Neuroscience and Biochemistry, Genetics and Molecular Biology.

The main research contributions cover these topics:

  • Neuroscience and Neuropharmacology Research
  • Neural dynamics and brain function
  • Neurogenesis and neuroplasticity mechanisms
  • Memory and Neural Mechanisms
  • Neuroscience and Neural Engineering
  • Photoreceptor and optogenetics research
  • Single-cell and spatial transcriptomics

Their publications investigate cellular and molecular neuroscience alongside cognitive and developmental neuroscience. Notable subfields include:

  • Cellular and Molecular Neuroscience
  • Molecular Biology
  • Cognitive Neuroscience
  • Developmental Neuroscience
  • Genetics

Chris J. McBain has authored numerous papers in respected venues, with recent notable publications including:

  • "Structure, Function, and Pharmacology of Glutamate Receptor Ion Channels" (2021) in Pharmacological Reviews
  • "Viral manipulation of functionally distinct interneurons in mice, non-human primates and humans" (2020) in Nature Neuroscience
  • "Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines: Prevalence of Germline Recombination and Influencing Factors" (2020) in Neuron
  • "Activity-dependent tuning of intrinsic excitability in mouse and human neurogliaform cells" (2020) in eLife
  • "Paradoxical network excitation by glutamate release from VGluT3+ GABAergic interneurons" (2020) in eLife

Frequent coauthors with whom Chris J. McBain has collaborated include Kenneth A. Pelkey, Ramesh Chittajallu, Xiaoqing Yuan, Steven Hunt, and Geoffrey Vargish.

The researcher's work has been published mainly in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Neuron
  • eLife
  • SSRN Electronic Journal
  • Nature Neuroscience

Best Publications

  • Glutamate Receptor Ion Channels: Structure, Regulation, and Function

    Stephen Traynelis;Lonnie P. Wollmuth;Chris J. McBain;Frank S. Menniti

  • N-methyl-D-aspartic acid receptor structure and function

    C. J. McBain;M. L. Mayer

  • The Role of the GluR2 Subunit in AMPA Receptor Function and Synaptic Plasticity

    John T.R. Isaac;Michael C. Ashby;Chris J. McBain

  • Young Dentate Granule Cells Mediate Pattern Separation, whereas Old Granule Cells Facilitate Pattern Completion

    Toshiaki Nakashiba;Jesse D. Cushman;Kenneth A. Pelkey;Sophie Renaudineau

  • New insights into the classification and nomenclature of cortical GABAergic interneurons

    Javier DeFelipe;Pedro L. López-Cruz;Ruth Benavides-Piccione;Ruth Benavides-Piccione;Concha Bielza

  • Kv3 channels: voltage-gated K+ channels designed for high-frequency repetitive firing

    Bernardo Rudy;Chris J. McBain

  • Hippocampal GABAergic Inhibitory Interneurons.

    Kenneth A. Pelkey;Ramesh Chittajallu;Michael T. Craig;Ludovic Tricoire;Ludovic Tricoire

  • Transient incorporation of native GluR2-lacking AMPA receptors during hippocampal long-term potentiation

    Karen Plant;Kenneth A Pelkey;Zuner A Bortolotto;Daiju Morita;Daiju Morita

  • Graded reduction of Pafah1b1 (Lis1) activity results in neuronal migration defects and early embryonic lethality

    Shinji Hirotsune;Mark W. Fleck;Michael J. Gambello;Gregory J. Bix

  • Structure, Function, and Pharmacology of Glutamate Receptor Ion Channels.

    Kasper B. Hansen;Lonnie P. Wollmuth;Derek Bowie;Hiro Furukawa

  • Excitatory amino acid receptors in epilepsy

    Raymond Dingledine;Chris J. McBain;James O. McNamara

  • Interneurons unbound

    Unknown

  • Social Interaction and Sensorimotor Gating Abnormalities in Mice Lacking Dvl1

    Nardos Lijam;Richard Paylor;Michael P. McDonald;Jacqueline N. Crawley

  • The hyperpolarization-activated current (Ih) and its contribution to pacemaker activity in rat CA1 hippocampal stratum oriens-alveus interneurones.

    Gianmaria Maccaferri;Chris J. McBain

  • Oligodendrocyte progenitor cell proliferation and lineage progression are regulated by glutamate receptor-mediated K+ channel block

    Vittorio Gallo;Jia Min Zhou;Chris J. McBain;Paul Wright

  • Activation of metabotropic glutamate receptors differentially affects two classes of hippocampal interneurons and potentiates excitatory synaptic transmission

    Chris J. McBain;Timothy J. DiChiara;Julie A. Kauer

  • Narp regulates homeostatic scaling of excitatory synapses on parvalbumin-expressing interneurons.

    Michael C Chang;Joo Min Park;Kenneth A Pelkey;Heidi L Grabenstatter

  • A Blueprint for the Spatiotemporal Origins of Mouse Hippocampal Interneuron Diversity

    Ludovic Tricoire;Kenneth A. Pelkey;Brian E. Erkkila;Brian W. Jeffries

  • Regional Variation of Extracellular Space in the Hippocampus

    Chris J. McBain;Stephen F. Traynelis;Raymond Dingledine

  • A role for glutamate and its receptors in the regulation of oligodendrocyte development in cerebellar tissue slices

    Xiaoqing Yuan;Alex M. Eisen;Chris J. McBain;Vittorio Gallo

  • Differential Mechanisms of Transmission at Three Types of Mossy Fiber Synapse

    Katalin Toth;Gregory Suares;J. Josh Lawrence;Emily Philips-Tansey

  • NPTX2 and cognitive dysfunction in Alzheimer’s Disease

    Mei Fang Xiao;Desheng Xu;Michael T. Craig;Kenneth A. Pelkey

Frequent Co-Authors

Kenneth A. Pelkey
Kenneth A. Pelkey National Institutes of Health
Ramesh Chittajallu
Ramesh Chittajallu National Institutes of Health
Raymond Dingledine
Raymond Dingledine Emory University
Ronald S. Petralia
Ronald S. Petralia National Institutes of Health
Gord Fishell
Gord Fishell Harvard Medical School
John T.R. Isaac
John T.R. Isaac Johnson & Johnson (United States)
Paul F. Worley
Paul F. Worley Johns Hopkins University School of Medicine
Bernardo Rudy
Bernardo Rudy New York University
Kareem A. Zaghloul
Kareem A. Zaghloul National Institutes of Health

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