World's Best Scientists 2026 revealed!
Raymond Dingledine

Raymond Dingledine

D-Index & Metrics

Neuroscience

D-Index
91
Citations
37959
World Ranking
1057
National Ranking
554

Research.com Recognitions

  • 2010 - Member of the National Academy of Medicine (NAM)
  • 2003 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1978 - Fellow of Alfred P. Sloan Foundation

Overview

Raymond Dingledine is affiliated with Emory University in the United States and has contributed extensively to the fields of neuroscience, medicine, and biochemistry, genetics, and molecular biology. Their research spans multiple subfields, including cellular and molecular neuroscience, molecular biology, neurology, pharmacology, and physiology.

Their work focuses on topics such as neuroscience and neuropharmacology research, neuroinflammation and neurodegeneration mechanisms, receptor mechanisms and signaling, inflammatory mediators and NSAID effects, epilepsy research and treatment, neuropeptides and animal physiology, and autoimmune neurological disorders and treatments.

Recent publications include:

  • "Peripheral Myeloid Cell EP2 Activation Contributes to the Deleterious Consequences of Status Epilepticus" (2020, Journal of Neuroscience)
  • "Seizures and memory impairment induced by patient-derived anti-N-methyl-D-aspartate receptor antibodies in mice are attenuated by anakinra, an interleukin-1 receptor antagonist" (2021, Epilepsia)
  • "Monoclonal Antibodies From Anti-NMDA Receptor Encephalitis Patient as a Tool to Study Autoimmune Seizures" (2021, Frontiers in Neuroscience)
  • "Potent, Selective, Water Soluble, Brain-Permeable EP2 Receptor Antagonist for Use in Central Nervous System Disease Models" (2020, Journal of Medicinal Chemistry)
  • "Comparison of neuropathology in rats following status epilepticus induced by diisopropylfluorophosphate and soman" (2020, NeuroToxicology)

Frequent coauthors in their research include:

  • Thota Ganesh
  • Radhika Amaradhi
  • Nicholas H. Varvel
  • Avijit Banik
  • Asheebo Rojas

The scientist's work has appeared frequently in publication venues such as UNC Libraries, IUPHAR/BPS Guide to Pharmacology CITE, Journal of Neuroscience, Epilepsia, and NeuroToxicology. Their contributions have helped expand understanding in several complex biomedical domains, particularly those related to neurological disorders and inflammation.

Raymond Dingledine has received several formal recognitions, including being named a Member of the National Academy of Medicine in 2010, a Fellow of the American Association for the Advancement of Science in 2003, and a Fellow of the Alfred P. Sloan Foundation in 1978.

Best Publications

  • THE GLUTAMATE RECEPTOR ION CHANNELS

    Raymond Dingledine;Karin Borges;Derek Bowie;Stephen F. Traynelis

  • Glutamate Receptor Ion Channels: Structure, Regulation, and Function

    Stephen Traynelis;Lonnie P. Wollmuth;Chris J. McBain;Frank S. Menniti

  • Requirement for glycine in activation of NMDA-receptors expressed in Xenopus oocytes

    Nancy W. Kleckner;Raymond Dingledine

  • Identification of a site in glutamate receptor subunits that controls calcium permeability.

    Richard I. Hume;Raymond Dingledine;Stephen F. Heinemann

  • Mitochondrial biogenesis in the anticonvulsant mechanism of the ketogenic diet.

    Kristopher J. Bough;Kristopher J. Bough;Jonathon Wetherington;Bjørnar Hassel;Jean Francois Pare

  • Potassium-induced spontaneous electrographic seizures in the rat hippocampal slice

    S. F. Traynelis;R. Dingledine

  • Excitatory amino acid receptors in epilepsy

    Raymond Dingledine;Chris J. McBain;James O. McNamara

  • Two different responses of hippocampal pyramidal cells to application of gamma-amino butyric acid.

    P Andersen;R Dingledine;L Gjerstad;I A Langmoen

  • The role of inflammation in epileptogenesis

    Annamaria Vezzani;Alon Friedman;Raymond J. Dingledine

  • Opiates and endogenous opioid peptides: by H. W. Kosterlitz, published by NorthHolland Publishing Company, Amsterdam/ New York/Oxford,1976. Df.95.- ($36.50) (x+456 pages)

    John S. Kelly;Ray Dingledine

  • Transcriptional repression by REST: recruitment of Sin3A and histone deacetylase to neuronal genes

    Yunfei Huang;Scott J. Myers;Raymond Dingledine

  • Astrocytes in the Epileptic Brain

    Jonathon Wetherington;Geidy Serrano;Ray Dingledine

  • Neuronal and glial pathological changes during epileptogenesis in the mouse pilocarpine model.

    Karin Borges;Marla Gearing;Dayna L McDermott;Amy B Smith

  • Naloxone as a GABA antagonist: evidence from iontophoretic, receptor binding and convulsant studies.

    Raymond Dingledine;Leslie L. Iversen;Ellen Breuker

  • Topology profile for a glutamate receptor: Three transmembrane domains and a channel-lining reentrant membrane loop

    Julie A Bennett;Raymond Dingledine

  • Involvement of N-methyl-D-aspartate receptors in epileptiform bursting in the rat hippocampal slice.

    R Dingledine;M A Hynes;G L King

  • Presynaptic inhibitory effect of acetylcholine in the hippocampus.

    RJ Valentino;R Dingledine

  • Differential Dependence on GluR2 Expression of Three Characteristic Features of AMPA Receptors

    Mark S. Washburn;Markus Numberger;Sunan Zhang;Raymond Dingledine

  • Altered Histone Acetylation at Glutamate Receptor 2 and Brain-Derived Neurotrophic Factor Genes Is an Early Event Triggered by Status Epilepticus

    Yunfei Huang;James J. Doherty;Ray Dingledine

  • N‐methyl aspartate activates voltage‐dependent calcium conductance in rat hippocampal pyramidal cells.

    R Dingledine

Frequent Co-Authors

Chris J. McBain
Chris J. McBain National Institutes of Health
Karin Borges
Karin Borges University of Queensland
Annamaria Vezzani
Annamaria Vezzani Mario Negri Institute for Pharmacological Research
Leif Gjerstad
Leif Gjerstad Oslo University Hospital
Hongjie Yuan
Hongjie Yuan Emory University
James O McNamara
James O McNamara Duke University
Rita J. Valentino
Rita J. Valentino National Institute on Drug Abuse
Yoland Smith
Yoland Smith Emory University
Amy R. Brooks-Kayal
Amy R. Brooks-Kayal University of Colorado Denver
Stephen F. Heinemann
Stephen F. Heinemann Salk Institute for Biological Studies

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