World's Best Scientists 2026 revealed!
James O McNamara

James O McNamara

D-Index & Metrics

Neuroscience

D-Index
96
Citations
32380
World Ranking
864
National Ranking
467

Medicine

D-Index
96
Citations
32467
World Ranking
9704
National Ranking
4994

Research.com Recognitions

  • 2013 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2005 - Member of the National Academy of Medicine (NAM)

Overview

James O McNamara is currently affiliated with Duke University in the United States. Their research spans multiple areas within medicine and biochemistry, genetics, and molecular biology.

McNamara's recent publications reflect a focus on neuroscience, infectious diseases, and molecular biology. Selected papers include:

  • "Toward the full potential of mRNA therapeutics," 2024, Molecular Therapy
  • "A fluorogenic micrococcal nuclease-based probe for fast detection and optical imaging of Staphylococcus aureus in prosthetic joint and fracture-related infections," 2023, European Journal of Nuclear Medicine and Molecular Imaging
  • "Social science for conservation in working landscapes and seascapes," 2022, Frontiers in Conservation Science
  • "Intravenous kainic acid induces status epilepticus and late onset seizures in mice," 2021, Epilepsy Research
  • "The smart activatable P2&3TT probe allows accurate, fast, and highly sensitive detection of Staphylococcus aureus in clinical blood culture samples," 2020, Scientific Reports

The scientist frequently publishes in venues such as bioRxiv (Cold Spring Harbor Laboratory), Epilepsy Research, European Journal of Nuclear Medicine and Molecular Imaging, European Journal of Cancer, and Frontiers in Conservation Science.

McNamara often collaborates with coauthors including George J Augustine, Lawrence C Katz, Anthony-Samuel LaMantia, Dale Purves, and David Fitzpatrick, with multiple joint publications across these collaborators.

Their work contributes to several fields of study, predominantly:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Subfields of McNamara's research include:

  • Molecular Biology
  • Cellular and Molecular Neuroscience
  • Surgery
  • Infectious Diseases
  • Genetics

Among the main topics covered in their research are:

  • Neuroscience and Neuropharmacology Research
  • Epilepsy research and treatment
  • Land Use and Ecosystem Services
  • Conservation, Biodiversity, and Resource Management
  • Economic and Environmental Valuation
  • Lipid Membrane Structure and Behavior
  • Orthopedic Infections and Treatments

James O McNamara has been recognized as a Fellow of the American Association for the Advancement of Science (AAAS) since 2013. They are also a member of the National Academy of Medicine since 2005.

Best Publications

  • Comparison of carbamazepine, phenobarbital, phenytoin, and primidone in partial and secondarily generalized tonic-clonic seizures

    Mattson Rh;Cramer Ja;Collins Jf;Smith Db

  • Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras.

    James O McNamara;Eran R Andrechek;Yong Wang;Kristi D Viles

  • Remote control of neuronal activity in transgenic mice expressing evolved G protein-coupled receptors.

    Georgia M. Alexander;Sarah C. Rogan;Atheir I. Abbas;Blaine N. Armbruster

  • Cellular and molecular basis of epilepsy

    JO McNamara

  • Autoantibodies to glutamate receptor GluR3 in Rasmussen's encephalitis

    SW Rogers;PI Andrews;LC Gahring;T Whisenand

  • Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors

    Justin P Dassie;Xiu-ying Liu;Gregory S Thomas;Ryan M Whitaker

  • VNS therapy in treatment-resistant depression: clinical evidence and putative neurobiological mechanisms.

    Charles B Nemeroff;Helen S Mayberg;Scott E Krahl;James McNamara

  • Excitatory amino acid receptors in epilepsy

    Raymond Dingledine;Chris J. McBain;James O. McNamara

  • Importance of the Intracellular Domain of NR2 Subunits for NMDA Receptor Function In Vivo

    Rolf Sprengel;Bettina Suchanek;Carla Amico;Rossella Brusa

  • Requirement for superoxide in excitotoxic cell death.

    Manisha Patel;Brian J. Day;James D. Crapo;Irwin Fridovich

  • Emerging insights into the genesis of epilepsy.

    James O. McNamara

  • Impairment of synaptic vesicle clustering and of synaptic transmission, and increased seizure propensity, in synapsin I-deficient mice.

    L Li;L S Chin;O Shupliakov;L Brodin

  • Mutant mice and neuroscience: Recommendations concerning genetic background

    Alcino J. Silva;Elizabeth M. Simpson;Joseph S. Takahashi;Hans Peter Lipp

  • Evidence implicating substantia nigra in regulation of kindled seizure threshold.

    J. O. Mcnamara;M. T. Galloway;L. C. Rigsbee;Cheolsu Shin

  • Anticonvulsant and antiepileptogenic actions of MK-801 in the kindling and electroshock models.

    J.O. McNamara;R.D. Russell;R.D. Russell;L. Rigsbee;D.W. Bonhaus;D.W. Bonhaus

  • The kindling model of epilepsy: A review

    James O. McNamara;M. Constant Byrne;Richard M. Dasheiff;J. Gregory Fitz

  • Zinc-Mediated Transactivation of TrkB Potentiates the Hippocampal Mossy Fiber-CA3 Pyramid Synapse

    Yang Z. Huang;Enhui Pan;Zhi-Qi Xiong;James O. McNamara

  • Ionotropic glutamate receptor subtypes activate c-fos transcription by distinct calcium-requiring intracellular signaling pathways

    Leslie S. Lerea;Leslie S. Lerea;James O. McNamara;James O. McNamara

  • Multivalent 4-1BB binding aptamers costimulate CD8+ T cells and inhibit tumor growth in mice

    James O. McNamara;Despina Kolonias;Fernando Pastor;Robert S. Mittler

  • Conditional Deletion of TrkB but Not BDNF Prevents Epileptogenesis in the Kindling Model

    Xiao Ping He;Robert Kotloski;Serge Nef;Bryan W. Luikart

Frequent Co-Authors

George J Augustine
George J Augustine Nanyang Technological University
Dale Purves
Dale Purves Duke University
J. Victor Nadler
J. Victor Nadler Duke University
Eli Gilboa
Eli Gilboa University of Miami
Lynne M. Mofenson
Lynne M. Mofenson Elizabeth Glaser Pediatric AIDS Foundation
Ryohei Yasuda
Ryohei Yasuda Max Planck Society
Bruce A. Sullenger
Bruce A. Sullenger Duke University
Rodney A. Radtke
Rodney A. Radtke Duke University
Raymond Dingledine
Raymond Dingledine Emory University

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