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Michele Simonato

Michele Simonato

D-Index & Metrics

Neuroscience

D-Index
48
Citations
7124
World Ranking
6258
National Ranking
321

Overview

Michele Simonato is affiliated with the University of Ferrara in Italy. Their research primarily focuses on the fields of Biochemistry, Genetics and Molecular Biology, Neuroscience, and Medicine. Within these disciplines, their work encompasses subfields such as Molecular Biology, Cellular and Molecular Neuroscience, Genetics, Psychiatry and Mental health, and Neurology.

The main topics that define their scholarly contributions include Neuroscience and Neuropharmacology Research, Epilepsy research and treatment, RNA Interference and Gene Delivery, Virus-based gene therapy research, CRISPR and Genetic Engineering, Neurogenesis and neuroplasticity mechanisms, and MicroRNA in disease regulation.

Frequently collaborating with other researchers, Michele Simonato has coauthored multiple papers with Silvia Zucchini, Barbara Bettegazzi, Marie Soukupovà, Stefano Cattaneo, and Annunziata Guarino. Their publications appear in several notable journals including EMBO Reports, Epilepsy Research, Nature Reviews Neurology, Proceedings of the National Academy of Sciences, and Frontiers in Molecular Neuroscience.

Significant recent papers authored or coauthored by Michele Simonato include:

  • Identification of clinically relevant biomarkers of epileptogenesis - a strategic roadmap, 2021, Nature Reviews Neurology

Other relevant papers appearing alongside their research are:

  • Antipsychotic drugs counteract autophagy and mitophagy in multiple sclerosis, 2021, Proceedings of the National Academy of Sciences
  • NPY and Gene Therapy for Epilepsy: How, When,... and Y, 2021, Frontiers in Molecular Neuroscience
  • SREBP2 gene therapy targeting striatal astrocytes ameliorates Huntington's disease phenotypes, 2021, Brain
  • The Dichotomous Role of Inflammation in the CNS: A Mitochondrial Point of View, 2020, Biomolecules

Best Publications

  • Advances in the development of biomarkers for epilepsy

    Asla Pitkänen;Wolfgang Löscher;Annamaria Vezzani;Albert J Becker

  • Progress in gene therapy for neurological disorders

    Michele Simonato;Jean Bennett;Nicholas M. Boulis;Maria G. Castro

  • Identification of new epilepsy treatments: Issues in preclinical methodology

    Aristea S. Galanopoulou;Paul S. Buckmaster;Kevin J. Staley;Solomon L. Moshé

  • Systems genetics identifies Sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus

    Michael R. Johnson;Jacques Behmoaras;Leonardo Bottolo;Michelle L. Krishnan

  • BDNF mRNA splice variants display activity-dependent targeting to distinct hippocampal laminae

    C. Chiaruttini;M. Sonego;G. Baj;M. Simonato

  • Brain-derived neurotrophic factor mRNA and protein are targeted to discrete dendritic laminas by events that trigger epileptogenesis.

    Enrico Tongiorgi;Mara Armellin;Piero Giulio Giulianini;Gianni Bregola

  • Gene Therapy Tools for Brain Diseases.

    Selene Ingusci;Gianluca Verlengia;Gianluca Verlengia;Marie Soukupova;Silvia Zucchini

  • Localized delivery of fibroblast growth factor–2 and brain-derived neurotrophic factor reduces spontaneous seizures in an epilepsy model

    Beatrice Paradiso;Peggy Marconi;Silvia Zucchini;Elena Berto

  • Blockade of Nociceptin/Orphanin FQ Transmission Attenuates Symptoms and Neurodegeneration Associated with Parkinson's Disease

    Matteo Marti;Flora Mela;Martina Fantin;Silvia Zucchini

  • Differential expression of immediate early genes in the hippocampus in the kindling model of epilepsy.

    Michele Simonato;David A. Hosford;David M. Labiner;Cheolsu Shin

  • Hippocampal FGF-2 and BDNF overexpression attenuates epileptogenesis-associated neuroinflammation and reduces spontaneous recurrent seizures

    Roberta Bovolenta;Silvia Zucchini;Beatrice Paradiso;Donata Rodi

  • Angels and demons: neurotrophic factors and epilepsy.

    Michele Simonato;Enrico Tongiorgi;Merab Kokaia

  • MicroRNA profiles in hippocampal granule cells and plasma of rats with pilocarpine-induced epilepsy – comparison with human epileptic samples

    Paolo Roncon;Marie Soukupovà;Anna Binaschi;Chiara Falcicchia

  • Finding a better drug for epilepsy: Antiepileptogenesis targets

    Katja Kobow;Stéphane Auvin;Frances Jensen;Wolfgang Löscher

  • The challenge and promise of anti-epileptic therapy development in animal models

    Michele Simonato;Amy R Brooks-Kayal;Jerome Engel;Aristea S Galanopoulou

  • Antinociceptive Activity of the N-Methyl-d-aspartate Receptor Antagonist N-(2-Indanyl)-glycinamide Hydrochloride (CHF3381) in Experimental Models of Inflammatory and Neuropathic Pain

    Gino Villetti;Marco Bergamaschi;Franco Bassani;Pier Tonino Bolzoni

  • DYNORPHIN AND EPILEPSY

    Michele Simonato;Patrizia Romualdi

  • Opportunities for improving animal welfare in rodent models of epilepsy and seizures

    Katie Lidster;John G. Jefferys;Ingmar Blümcke;Vincenzo Crunelli

  • Acetylcholine content in rat brain is elevated by status epilepticus induced by lithium and pilocarpine.

    Richard S. Jope;Michele Simonato;Kathleen Lally

  • Seizure-Suppressant and Neuroprotective Effects of Encapsulated BDNF-Producing Cells in a Rat Model of Temporal Lobe Epilepsy.

    Chiara Falcicchia;Giovanna Paolone;Dwaine F. Emerich;Francesca Lovisari

  • Gene transfer into neurones for the molecular analysis of behaviour: focus on herpes simplex vectors

    Michele Simonato;Roberto Manservigi;Peggy Marconi;Joseph Glorioso

Frequent Co-Authors

Lorenzo Beani
Lorenzo Beani University of Ferrara
Asla Pitkänen
Asla Pitkänen University of Eastern Finland
Joseph C. Glorioso
Joseph C. Glorioso University of Pittsburgh
Sergio Tanganelli
Sergio Tanganelli University of Ferrara
Merab Kokaia
Merab Kokaia Lund University
Michele Morari
Michele Morari University of Ferrara
Enrico Tongiorgi
Enrico Tongiorgi University of Trieste
Annamaria Vezzani
Annamaria Vezzani Mario Negri Institute for Pharmacological Research
Eleonora Aronica
Eleonora Aronica University of Amsterdam
Tiziana Antonelli
Tiziana Antonelli University of Ferrara

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