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Michele Morari

Michele Morari

D-Index & Metrics

Neuroscience

D-Index
49
Citations
6959
World Ranking
6057
National Ranking
310

Overview

Michele Morari is affiliated with the University of Ferrara in Italy and has contributed extensively to research in medicine and neuroscience. Their academic work primarily focuses on neurology and cellular and molecular neuroscience, with additional insights into physiology, molecular biology, and epidemiology.

The main topics of their research include:

  • Parkinson's Disease Mechanisms and Treatments
  • Neurological disorders and treatments
  • Neuroscience and Neuropharmacology Research
  • Nuclear Receptors and Signaling
  • Receptor Mechanisms and Signaling
  • Neurotransmitter Receptor Influence on Behavior
  • Neurological diseases and metabolism

Among recent publications authored or co-authored by Michele Morari are:

  • "Identification of distinct pathological signatures induced by patient-derived α-synuclein structures in nonhuman primates", 2020, Science Advances
  • "Mitochondrial P2X7 Receptor Localization Modulates Energy Metabolism Enhancing Physical Performance", 2021, Function
  • "Translation Imaging in Parkinson's Disease: Focus on Neuroinflammation", 2020, Frontiers in Aging Neuroscience
  • "Safinamide inhibits in vivo glutamate release in a rat model of Parkinson's disease", 2020, Neuropharmacology
  • "LRRK2 G2019S kinase activity triggers neurotoxic NSF aggregation", 2021, Brain

Michele Morari has published frequently in several scientific venues, including:

  • Neurobiology of Disease
  • Brain
  • Science Advances
  • Biomedicines
  • Scientific Reports

The scientist collaborates regularly with a group of co-authors, reflecting a network of research activity in their field. Frequent collaborators include:

  • Daniela Mercatelli
  • Salvatore Novello
  • Alberto Brugnoli
  • Federica Albanese
  • Chiara Domenicale

The research profile of Michele Morari is marked by a consistent focus on neurological disease mechanisms, especially Parkinson's disease, through multiple interdisciplinary approaches combining molecular biology, neuropharmacology, and physiology.

Best Publications

  • Pathophysiology of L-dopa-induced motor and non-motor complications in Parkinson's disease.

    Matthieu F. Bastide;Wassilios G. Meissner;Barbara Picconi;Stefania Fasano

  • Antagonism of metabotropic glutamate receptor type 5 attenuates l-DOPA-induced dyskinesia and its molecular and neurochemical correlates in a rat model of Parkinson's disease.

    Flora Mela;Matteo Marti;Andrzej Dekundy;Wojciech Danysz

  • N-methyl-D-aspartic acid differentially regulates extracellular dopamine, GABA, and glutamate levels in the dorsolateral neostriatum of the halothane-anesthetized rat: an in vivo microdialysis study.

    M. Morari;W. T. O'Connor;U. Ungerstedt;K. Fuxe

  • Solid Lipid Nanoparticles as Delivery Systems for Bromocriptine

    Elisabetta Esposito;Martina Fantin;Matteo Marti;Markus Drechsler

  • [Nphe1,Arg14,Lys15]nociceptin-NH2, a novel potent and selective antagonist of the nociceptin/orphanin FQ receptor.

    Girolamo Calo;Anna Rizzi;Daniela Rizzi;Raffaella Bigoni

  • Reciprocal dopamine-glutamate modulation of release in the basal ganglia.

    Michele Morari;Matteo Marti;Simone Sbrenna;K. Fuxe

  • Glutamate antagonists prevent morphine withdrawal in mice and guinea pigs

    S. Tanganelli;T. Antonelli;M. Morari;C. Bianchi

  • Nociceptin/orphanin FQ and neurotransmitter release in the central nervous system.

    E. Schlicker;M. Morari

  • Mechanisms underlying the impairment of hippocampal long-term potentiation and memory in experimental Parkinson’s disease

    Cinzia Costa;Carmelo Sgobio;Sabrina Siliquini;Alessandro Tozzi

  • Blockade of nociceptin/orphanin FQ receptor signaling in rat substantia nigra pars reticulata stimulates nigrostriatal dopaminergic transmission and motor behavior.

    Matteo Marti;Flora Mela;Carlo Veronesi;Remo Guerrini

  • Blockade of Nociceptin/Orphanin FQ Transmission Attenuates Symptoms and Neurodegeneration Associated with Parkinson's Disease

    Matteo Marti;Flora Mela;Martina Fantin;Silvia Zucchini

  • Nanoparticulate lipid dispersions for bromocriptine delivery: characterization and in vivo study.

    Elisabetta Esposito;Paolo Mariani;Laura Ravani;Catia Contado

  • Pharmacological Characterization of the Nociceptin/Orphanin FQ Receptor Antagonist SB-612111 [(–)-cis-1-Methyl-7-[[4-(2,6-dichlorophenyl)piperidin-1-yl]methyl]-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-ol]: In Vitro Studies

    Barbara Spagnolo;Giacomo Carrà;Martina Fantin;Carmela Fischetti

  • LRRK2 kinase activity regulates synaptic vesicle trafficking and neurotransmitter release through modulation of LRRK2 macro-molecular complex

    Maria D. Cirnaru;Antonella Marte;Elisa Belluzzi;Isabella Russo

  • Modulation of 5-hydroxytryptamine efflux from rat cortical synaptosomes by opioids and nociceptin.

    S Sbrenna;M Marti;M Morari;G Calo

  • Age-dependent dopamine transporter dysfunction and Serine129 phospho-α-synuclein overload in G2019S LRRK2 mice

    Francesco Longo;Daniela Mercatelli;Salvatore Novello;Ludovico Arcuri

  • L-dopa-induced dyskinesia: beyond an excessive dopamine tone in the striatum

    Gregory Porras;Philippe De Deurwaerdere;Qin Li;Matteo Marti

  • Amantadine attenuates levodopa‐induced dyskinesia in mice and rats preventing the accompanying rise in nigral GABA levels

    Simone Bido;Matteo Marti;Michele Morari

  • Dopamine D1 and D2 receptor antagonism differentially modulates stimulation of striatal neurotransmitter levels by N-methyl-D-aspartic acid

    Michele Morari;William T. O'Connor;Urban Ungerstedt;Kjell Fuxe

  • Functional neuroanatomy of the nigrostriatal and striatonigral pathways as studied with dual probe microdialysis in the awake rat--II. Evidence for striatal N-methyl-D-aspartate receptor regulation of striatonigral GABAergic transmission and motor function.

    M. Morari;W.T. O'Connor;U. Ungerstedt;C. Bianchi

Frequent Co-Authors

Lorenzo Beani
Lorenzo Beani University of Ferrara
Riccardo Brambilla
Riccardo Brambilla Cardiff University
Kjell Fuxe
Kjell Fuxe Karolinska Institute
Michele Simonato
Michele Simonato University of Ferrara
Luca Ferraro
Luca Ferraro University of Ferrara
Sergio Tanganelli
Sergio Tanganelli University of Ferrara
Paolo Calabresi
Paolo Calabresi Catholic University of the Sacred Heart
Alessandro Tozzi
Alessandro Tozzi University of Perugia
Tiziana Antonelli
Tiziana Antonelli University of Ferrara
Markus Drechsler
Markus Drechsler University of Bayreuth

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