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Kazuyoshi Kawakami

Kazuyoshi Kawakami

D-Index & Metrics

Biology and Biochemistry

D-Index
53
Citations
10802
World Ranking
16108
National Ranking
1149

Overview

Kazuyoshi Kawakami is affiliated with the University of the Ryukyus in Japan and has a research focus primarily in the field of Medicine, with a strong emphasis on Oncology. Their work spans several subfields including Oncology, Pulmonary and Respiratory Medicine, Surgery, Pharmacology, and Pathology and Forensic Medicine. The research output reflects a focus on cancer treatment and management, particularly involving chemotherapy and its side effects.

Their recent publications cover topics related to cancer pharmacology, adverse drug reactions, and chemotherapy-induced toxicity. Notable papers include:

  • Paclitaxel Induces Upregulation of Transient Receptor Potential Vanilloid 1 Expression in the Rat Spinal Cord (2020), published in International Journal of Molecular Sciences
  • Identification of hand-foot syndrome from cancer patients' blog posts: BERT-based deep-learning approach to detect potential adverse drug reaction symptoms (2022), published in PLoS ONE
  • Associations among plasma concentrations of regorafenib and its metabolites, adverse events, and ABCG2 polymorphisms in patients with metastatic colorectal cancers (2021), published in Cancer Chemotherapy and Pharmacology
  • Comparison of cisplatin-induced nephrotoxicity when using conventional versus short hydration in gastric cancer-a retrospective study (2020), published in Journal of Chemotherapy
  • National survey of physicians in Japan regarding their use of diagnostic tests for legionellosis (2021), published in Journal of Infection and Chemotherapy

Kawakami frequently collaborates with researchers such as Takeshi Aoyama, Takashi Yokokawa, Masakazu Yamaguchi, Kazuo Kobayashi, and Kensei Yamaguchi. These collaborations have contributed to a broad set of publications and reflect a network of research activity in oncology and pharmacology.

The scientist's work has appeared in several key journals including YAKUGAKU ZASSHI, PLoS ONE, Anticancer Research, Oncology, and Journal of Clinical Oncology. These venues have featured multiple publications, underscoring the consistent focus on cancer-related studies.

The areas of specialization can be summarized by the following research topics:

  • Colorectal Cancer Treatments and Studies
  • Gastric Cancer Management and Outcomes
  • Cancer Treatment and Pharmacology
  • Chemotherapy-induced organ toxicity mitigation
  • Neutropenia and Cancer Infections
  • Nausea and vomiting management
  • Pancreatic and Hepatic Oncology Research

Overall, the scholarly contributions of Kazuyoshi Kawakami center on clinical oncology with particular attention to the pharmacological management of cancer and the mitigation of treatment-related side effects. The research spans molecular mechanisms, clinical studies, and the use of emerging technologies such as deep learning for symptom detection.

Best Publications

  • Dectin-1 is required for host defense against Pneumocystis carinii but not against Candida albicans.

    Shinobu Saijo;Noriyuki Fujikado;Takahisa Furuta;Soo Hyun Chung

  • Dectin-2 Recognition of α-Mannans and Induction of Th17 Cell Differentiation Is Essential for Host Defense against Candida albicans

    Shinobu Saijo;Satoshi Ikeda;Keiko Yamabe;Shigeru Kakuta

  • IL-17-Mediated Regulation of Innate and Acquired Immune Response against Pulmonary Mycobacterium bovis Bacille Calmette-Guérin Infection

    Masayuki Umemura;Ayano Yahagi;Satoru Hamada;Mst Dilara Begum

  • IL-17A Produced by γδ T Cells Plays a Critical Role in Innate Immunity against Listeria monocytogenes Infection in the Liver

    Satoru Hamada;Masayuki Umemura;Takeru Shiono;Kensho Tanaka

  • A mechanism of erythromycin treatment in patients with diffuse panbronchiolitis.

    J Kadota;O Sakito;S Kohno;H Sawa

  • Invariant natural killer T cells recognize glycolipids from pathogenic Gram-positive bacteria

    Yuki Kinjo;Petr Illarionov;José Luis Vela;Bo Pei

  • Critical role of Vα14+ natural killer T cells in the innate phase of host protection against Streptococcus pneumoniae infection

    Kazuyoshi Kawakami;Natsuo Yamamoto;Yuki Kinjo;Kazuya Miyagi

  • IL-18 protects mice against pulmonary and disseminated infection with Cryptococcus neoformans by inducing IFN-gamma production.

    Kazuyoshi Kawakami;Mahboob Hossain Qureshi;Tiantuo Zhang;Haruki Okamura

  • Monocyte Chemoattractant Protein-1-Dependent Increase of Vα14 NKT Cells in Lungs and Their Roles in Th1 Response and Host Defense in Cryptococcal Infection

    Kazuyoshi Kawakami;Yuki Kinjo;Kaori Uezu;Satomi Yara

  • Activation of Vα14+ Natural Killer T Cells by α-Galactosylceramide Results in Development of Th1 Response and Local Host Resistance in Mice Infected with Cryptococcus neoformans

    Kazuyoshi Kawakami;Yuki Kinjo;Satomi Yara;Yoshinobu Koguchi

  • IL-12 protects mice against pulmonary and disseminated infection caused by Cryptococcus neoformans.

    K. Kawakami;M. Tohyama;Q. Xie;A. Saito

  • IL-18 Contributes to Host Resistance Against Infection with Cryptococcus neoformans in Mice with Defective IL-12 Synthesis Through Induction of IFN-γ Production by NK Cells

    Kazuyoshi Kawakami;Yoshinobu Koguchi;Mahboob Hossain Qureshi;Akiko Miyazato

  • Cryptococcal infection and Th1-Th2 cytokine balance.

    Yoshinobu Koguchi;Kazuyoshi Kawakami

  • Expression of cytokines and inducible nitric oxide synthase mRNA in the lungs of mice infected with Cryptococcus neoformans: effects of interleukin-12.

    Kazuyoshi Kawakami;Masaki Tohyama;Xie Qifeng;Andatsushi Saito

  • Deoxynucleic Acids from Cryptococcus neoformans Activate Myeloid Dendritic Cells via a TLR9-Dependent Pathway

    Kiwamu Nakamura;Akiko Miyazato;Gang Xiao;Masumitsu Hatta

  • Toll-Like Receptor 9-Dependent Activation of Myeloid Dendritic Cells by Deoxynucleic Acids from Candida albicans

    Akiko Miyazato;Akiko Miyazato;Kiwamu Nakamura;Natsuo Yamamoto;Héctor M. Mora-Montes

  • Role of reactive nitrogen and oxygen intermediates in gamma interferon- stimulated murine macrophage bactericidal activity against Burkholderia pseudomallei

    Kei Miyagi;Kazuyoshi Kawakami;Atsushi Saito

  • Dectin-1 is not required for the host defense to Cryptococcus neoformans.

    Kiwamu Nakamura;Kiwamu Nakamura;Takeshi Kinjo;Shinobu Saijo;Akiko Miyazato

  • OX40 ligand expressed by DCs costimulates NKT and CD4 + Th cell antitumor immunity in mice

    Jamal Zaini;Sita Andarini;Minoru Tahara;Yasuo Saijo

  • Lower expression of Th1-related cytokines and inducible nitric oxide synthase in mice with streptozotocin-induced diabetes mellitus infected with Mycobacterium tuberculosis.

    S. Yamashiro;Kazuyoshi Kawakami;K. Uezu;T. Kinjo

Frequent Co-Authors

Kiyoshi Takeda
Kiyoshi Takeda Osaka University
Shizuo Akira
Shizuo Akira Osaka University
Yoichiro Iwakura
Yoichiro Iwakura Tokyo University of Science
Masashi Kurimoto
Masashi Kurimoto Okayama University
Shinobu Saijo
Shinobu Saijo Chiba University
Shigeru Kohno
Shigeru Kohno Nagasaki University
Toshinori Nakayama
Toshinori Nakayama Chiba University
Kazunori Oishi
Kazunori Oishi National Institutes of Health
Hiroshi Mukae
Hiroshi Mukae Nagasaki University
Masahiro Maeda
Masahiro Maeda Osaka University

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