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Gottfried Alber

Gottfried Alber

D-Index & Metrics

Immunology

D-Index
42
Citations
10916
World Ranking
4871
National Ranking
313

Overview

Gottfried Alber is affiliated with Leipzig University in Germany and has contributed extensively to the fields of medicine, immunology, and microbiology. Their research encompasses a range of topics including streptococcal infections and treatments, immune response and inflammation, as well as T-cell and B-cell immunology.

The scientist's work is prominently published in several journals, with frequent contributions to Frontiers in Immunology, where they have published eight papers. Other venues include Tierärztliche Praxis Ausgabe K Kleintiere / Heimtiere with three publications, Veterinary Research and BMC Veterinary Research each with two, and Veterinary Immunology and Immunopathology where they have one publication.

Main fields of study covered in their publications are medicine and immunology and microbiology. Subfields include immunology, public health, environmental and occupational health, epidemiology, pulmonary and respiratory medicine, and molecular biology.

Their recent research papers include:

  • Immunogenicity and protective efficacy of a Streptococcus suis vaccine composed of six conserved immunogens, 2021, Veterinary Research
  • Group 2 Innate Lymphoid Cells (ILC2) Suppress Beneficial Type 1 Immune Responses During Pulmonary Cryptococcosis, 2020, Frontiers in Immunology
  • Analysis of Porcine Pro- and Anti-Inflammatory Cytokine Induction by S. suis In Vivo and In Vitro, 2020, Pathogens
  • Canine peripheral blood TCRαβ T cell atlas: Identification of diverse subsets including CD8A+ MAIT-like cells by combined single-cell transcriptome and V(D)J repertoire analysis, 2023, Frontiers in Immunology
  • Immunoglobulin M-degrading enzyme of Streptococcus suis (IdeSsuis) impairs porcine B cell signaling, 2023, Frontiers in Immunology

Frequent co-authors collaborating with Gottfried Alber include Martina Protschka, Uwe Müller, Jöerg M. Steiner, Romy M. Heilmann, and Christoph Georg Baums.

The scientist's main research topics reflect a focus on streptococcal infections and treatments, immune response and inflammation, and T-cell and B-cell immunology. They have also investigated S100 proteins and annexins, toxin mechanisms and immunotoxins, neonatal and maternal infections, as well as fungal infections and studies.

Best Publications

  • Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation.

    M Cella;D Scheidegger;K Palmer-Lehmann;P Lane

  • Genetically resistant mice lacking interleukin-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response.

    Frank Mattner;Jeanne Magram;Jessica Ferrante;Pascal Launois

  • Interleukin-12 Is Essential for a Protective Th1 Response in Mice Infected with Cryptococcus neoformans

    Klaus Decken;Gabriele Köhler;Kathrin Palmer-Lehmann;Andrea Wunderlin

  • Novel IL-12 family members shed light on the orchestration of Th1 responses.

    Frank Brombacher;Robert A. Kastelein;Gottfried Alber

  • IL-13 induces disease-promoting type 2 cytokines, alternatively activated macrophages and allergic inflammation during pulmonary infection of mice with Cryptococcus neoformans.

    Uwe Müller;Werner Stenzel;Gabriele Köhler;Christoph Werner

  • A Protective and Agonistic Function of IL-12p40 in Mycobacterial Infection

    Christoph Hölscher;Robert A. Atkinson;Berenice Arendse;Najmeeyah Brown

  • IL-23 Enhances the Inflammatory Cell Response in Cryptococcus neoformans Infection and Induces a Cytokine Pattern Distinct from IL-12

    Melanie A. Kleinschek;Uwe Muller;Scott J. Brodie;Werner Stenzel

  • Structure-function relationships in the mast cell high affinity receptor for IgE. Role of the cytoplasmic domains and of the beta subunit.

    G Alber;L Miller;C L Jelsema;N Varin-Blank

  • IL-17A is produced by Th17, γδ T cells and other CD4− lymphocytes during infection with Salmonella enterica serovar Enteritidis and has a mild effect in bacterial clearance

    Silke M. Schulz;Gabriele Köhler;Christoph Holscher;Yoichiro Iwakura

  • Differential signaling through the Ig-α and Ig-β components of the B cell antigen receptor

    Kwang-Myong Kim;Gottfried Alber;Peter Weiser;Michael Reth

  • Timing and Magnitude of Type I Interferon Responses by Distinct Sensors Impact CD8 T Cell Exhaustion and Chronic Viral Infection

    Yaming Wang;Melissa Swiecki;Marina Cella;Gottfried Alber

  • IL-12p40-Dependent Agonistic Effects on the Development of Protective Innate and Adaptive Immunity Against Salmonella Enteritidis

    Jörg Lehmann;Steffi Bellmann;Christoph Werner;Regina Schröder

  • αβ T Cell Receptor-positive Cells and Interferon-γ, but not Inducible Nitric Oxide Synthase, Are Critical for Granuloma Necrosis in a Mouse Model of Mycobacteria-induced Pulmonary Immunopathology

    Stefan Ehlers;Jochen Benini;Heinz-Dieter Held;Christiane Roeck

  • Mice Lacking IL-12 Develop Polarized Th1 Cells During Viral Infection

    Virgil E. C. J. Schijns;Bart L. Haagmans;Christel M. H. Wierda;Boudewijn Kruithof

  • Protective Immunity to Systemic Infection with Attenuated Salmonella enterica serovar Enteritidis in the Absence of IL-12 Is Associated with IL-23-Dependent IL-22, but Not IL-17

    Silke M. Schulz;Gabriele Köhler;Nicole Schütze;Jens Knauer

  • Dendritic Cell (DC)-Based Protection Against an Intracellular Pathogen Is Dependent Upon DC-Derived IL-12 and Can Be Induced by Molecularly Defined Antigens

    Christof Berberich;José R. Ramírez-Pineda;Christine Hambrecht;Gottfried Alber

  • IL-12 is dispensable for innate and adaptive immunity against low doses of Listeria monocytogenes

    Frank Brombacher;Andreas Dorfmüller;Jeanne Magram;Wen Juan Dai

  • Immunomodulatory Effects of Viral TLR Ligands on Experimental Asthma Depend on the Additive Effects of IL-12 and IL-10

    Serdar Sel;Michael Wegmann;Sarper Sel;Stefan Bauer

  • The Innate Immune System of Mammals and Insects

    Uwe Müller;Patric Vogel;Gottfried Alber;Günter A. Schaub

  • Api88 Is a Novel Antibacterial Designer Peptide To Treat Systemic Infections with Multidrug-Resistant Gram-Negative Pathogens

    Patricia Czihal;Daniel Knappe;Stefanie Fritsche;Michael Zahn

  • IL-12 family members: differential kinetics of their TLR4-mediated induction by Salmonella Enteritidis and the impact of IL-10 in bone marrow-derived macrophages

    Nicole Schuetze;Sabine Schoeneberger;Uwe Mueller;Marina A. Freudenberg

  • Interplay between Alpha/Beta and Gamma Interferons with B, T, and Natural Killer Cells in the Defense against Herpes Simplex Virus Type 1

    Sabine Vollstedt;Susi Arnold;Cornelia Schwerdel;Marco Franchini

Frequent Co-Authors

Gabriele Köhler
Gabriele Köhler University of Münster
Frank Brombacher
Frank Brombacher University of Cape Town
Ralf Hoffmann
Ralf Hoffmann Leipzig University
Robert A. Kastelein
Robert A. Kastelein MSD (United States)
Peter F Moore
Peter F Moore University of California, Davis
Robert Sabat
Robert Sabat Charité - University Medicine Berlin
Bart L. Haagmans
Bart L. Haagmans Erasmus University Rotterdam
Thomas Kamradt
Thomas Kamradt Friedrich Schiller University Jena
Marina A. Freudenberg
Marina A. Freudenberg University of Freiburg
Mathias Ackermann
Mathias Ackermann University of Zurich

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