His primary areas of study are Immunology, Interleukin 22, Cytokine, Immune system and Cell biology. His Immunology study deals with Receptor intersecting with Interferon. His research integrates issues of Inflammatory bowel disease, T cell, Mesenteric lymph nodes, Lymph and Lipopolysaccharide binding protein in his study of Cytokine.
His research in Immune system intersects with topics in Virus, Clinical trial and Systemic inflammation. His studies deal with areas such as S100A7, Interleukin 12, IL-2 receptor and Regulation of gene expression as well as Cell biology. His IL-2 receptor study integrates concerns from other disciplines, such as Innate immune system and Innate lymphoid cell.
His primary areas of investigation include Immunology, Psoriasis, Cytokine, Interleukin 22 and Immune system. Inflammation, Interleukin, Interleukin 10, Tumor necrosis factor alpha and T cell are among the areas of Immunology where he concentrates his study. The study incorporates disciplines such as Antigen-presenting cell, Interferon, Dendritic cell, Receptor and Cell biology in addition to Cytokine.
His Cell biology research incorporates elements of Cell, Cytotoxic T cell, Interleukin 12, IL-2 receptor and Innate immune system. The IL-2 receptor study combines topics in areas such as Interleukin 21 and Innate lymphoid cell. His work deals with themes such as Signal transduction and Interleukin 17, which intersect with Interleukin 22.
Robert Sabat spends much of his time researching Psoriasis, Internal medicine, Hidradenitis suppurativa, Immunology and Tumor necrosis factor alpha. The various areas that Robert Sabat examines in his Psoriasis study include Bioinformatics, Pathogenesis, Keratinocyte, Drug and Immunotherapy. Many of his studies on Immunology apply to Cell type as well.
His Tumor necrosis factor alpha research includes elements of Receptor, Cancer research, Apoptosis and Cell growth. His study in Receptor is interdisciplinary in nature, drawing from both Interleukin, Molecular biology and Granulocyte. T cell, Innate lymphoid cell, Lymphokine and Monocyte is closely connected to Interleukin 22 in his research, which is encompassed under the umbrella topic of Interleukin 17.
Immunology, Hidradenitis suppurativa, Psoriasis, Immune system and Tumor necrosis factor alpha are his primary areas of study. Robert Sabat has included themes like Receptor and Downregulation and upregulation in his Immunology study. His Immune system study incorporates themes from Scars, Pathogenesis, Inflammation, Hyperkeratosis and Necrosis.
His Tumor necrosis factor alpha study combines topics from a wide range of disciplines, such as Cytokine, Transcriptome, microRNA, Messenger RNA and Cell type. As a part of the same scientific family, Robert Sabat mostly works in the field of Interleukin 17, focusing on Vitiligo and, on occasion, T cell. Robert Sabat combines subjects such as Interleukin 22, Melanoma and Atopic dermatitis with his study of T cell.
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IL-22 increases the innate immunity of tissues.
Kerstin Wolk;Stefanie Kunz;Ellen Witte;Markus Friedrich.
IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes : a potential role in psoriasis
Kerstin Wolk;Ellen Witte;Elizabeth Wallace;Wolf-Dietrich Döcke.
European Journal of Immunology (2006)
Biology of interleukin-10
Robert Sabat;Gerald Grütz;Katarzyna Warszawska;Stefan Kirsch.
Cytokine & Growth Factor Reviews (2010)
Cutting Edge: Immune Cells as Sources and Targets of the IL-10 Family Members?
Kerstin Wolk;Stefanie Kunz;Khusru Asadullah;Robert Sabat;Robert Sabat.
Journal of Immunology (2002)
Immunopathogenesis of psoriasis
Robert Sabat;Sandra Philipp;Conny Höflich;Stefanie Kreutzer.
Experimental Dermatology (2007)
IL-22 and IL-20 are key mediators of the epidermal alterations in psoriasis while IL-17 and IFN-γ are not
Kerstin Wolk;Harald S. Haugen;Wenfeng Xu;Ellen Witte.
Journal of Molecular Medicine (2009)
Biology of interleukin-22
Kerstin Wolk;Ellen Witte;Katrin Witte;Katarzyna Warszawska.
Seminars in Immunopathology (2010)
Therapeutic opportunities of the IL-22-IL-22R1 system.
Robert Sabat;Wenjun Ouyang;Kerstin Wolk.
Nature Reviews Drug Discovery (2014)
Interleukin-22: a novel T- and NK-cell derived cytokine that regulates the biology of tissue cells.
Kerstin Wolk;Robert Sabat.
Cytokine & Growth Factor Reviews (2006)
Impaired antigen presentation by human monocytes during endotoxin tolerance
Kerstin Wolk;Wolf-Dietrich Döcke;Volker von Baehr;Hans-Dieter Volk.
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