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Biology and Biochemistry

D-Index
45
Citations
11920
World Ranking
19052
National Ranking
308

Overview

Laure Dumoutier is affiliated with the Université Catholique de Louvain in Belgium. Their research primarily spans the fields of Medicine and Immunology and Microbiology, with a particular focus on immunology, infectious diseases, dermatology, oncology, and surgery.

The scientist has contributed to various topics including cytokine signaling pathways and interactions, dermatology and skin diseases, IL-33, ST2, and ILC pathways, COVID-19 clinical research studies, Clostridium difficile and Clostridium perfringens research, immune cell function and interaction, and immunotherapy and immune responses.

Frequent venues for Dumoutier's published works include bioRxiv (Cold Spring Harbor Laboratory), Frontiers in Immunology, European Journal of Immunology, Journal of Clinical Investigation, and Nature Communications.

Recent papers authored or co-authored by Dumoutier include:

  • Microenvironmental Th9 and Th17 lymphocytes induce metastatic spreading in lung cancer (2020), Journal of Clinical Investigation
  • Selective inhibition of STAT3 signaling using monobodies targeting the coiled-coil and N-terminal domains (2020), Nature Communications
  • Correlations between disease activity, autoimmunity and biological parameters in patients with chronic spontaneous urticaria (2020), European Annals of Allergy and Clinical Immunology
  • Ozone-Induced Aryl Hydrocarbon Receptor Activation Controls Lung Inflammation via Interleukin-22 Modulation (2020), Frontiers in Immunology
  • Loss of NFKB1 Results in Expression of Tumor Necrosis Factor and Activation of Signal Transducer and Activator of Transcription 1 to Promote Gastric Tumorigenesis in Mice (2020), Gastroenterology

Dumoutier frequently collaborates with a select group of co-authors, including Camille Michiels, Sandrine Horman, Luc Bertrand, Christophe Beauloye, and Marie Baeck.

Best Publications

  • The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins.

    Marc Veldhoen;Keiji Hirota;Astrid M. Westendorf;Jan Buer

  • Cloning and Characterization of IL-10-Related T Cell-Derived Inducible Factor (IL-TIF), a Novel Cytokine Structurally Related to IL-10 and Inducible by IL-9

    Laure Dumoutier;Jamila Louahed;Jean-Christophe Renauld

  • Cutting Edge: STAT Activation By IL-19, IL-20 and mda-7 Through IL-20 Receptor Complexes of Two Types

    Laure Dumoutier;Caroline Leemans;Diane Lejeune;Sergei V. Kotenko

  • Interleukin-22 (IL-22) activates the JAK/STAT, ERK, JNK, and p38 MAP kinase pathways in a rat hepatoma cell line. Pathways that are shared with and distinct from IL-10.

    Diane Lejeune;Laure Dumoutier;Stefan Constantinescu;Wiebe Kruijer

  • Human interleukin-10-related T cell-derived inducible factor: molecular cloning and functional characterization as an hepatocyte-stimulating factor.

    Laure Dumoutier;Emiel Van Roost;Didier Colau;Jean-Christophe Renauld

  • IL-22 Is Expressed by Th17 Cells in an IL-23-Dependent Fashion, but Not Required for the Development of Autoimmune Encephalomyelitis

    Katharina Kreymborg;Ruth Etzensperger;Laure Dumoutier;Laure Dumoutier;Stefan Haak

  • Interferon-lambda contributes to innate immunity of mice against influenza A virus but not against hepatotropic viruses

    Markus Mordstein;Georg Kochs;Laure Dumoutier;Jean-Christophe Renauld

  • Role of the interleukin (IL)-28 receptor tyrosine residues for antiviral and antiproliferative activity of IL-29/interferon-lambda 1: similarities with type I interferon signaling.

    Laure Dumoutier;Amel Tounsi;Thomas Michiels;Caroline Sommereyns

  • Cloning and Characterization of IL-22 Binding Protein, a Natural Antagonist of IL-10-Related T Cell-Derived Inducible Factor/IL-22

    Laure Dumoutier;Diane Lejeune;Didier Colau;Jean-Christophe Renauld

  • IL-22 Is Required for Imiquimod-Induced Psoriasiform Skin Inflammation in Mice

    Astrid B. Van Belle;Magali de Heusch;Magali de Heusch;Muriel M. Lemaire;Muriel M. Lemaire;Emilie Hendrickx;Emilie Hendrickx

  • Proinflammatory role of the Th17 cytokine interleukin-22 in collagen-induced arthritis in C57BL/6 mice

    Lies Geboes;Laure Dumoutier;Hilde Kelchtermans;Evelien Schurgers

  • Interferon-λ and interleukin 22 act synergistically for the induction of interferon-stimulated genes and control of rotavirus infection

    Pedro P Hernández;Pedro P Hernández;Tanel Mahlakõiv;Ines Yang;Vera Schwierzeck

  • IL-TIF/IL-22: genomic organization and mapping of the human and mouse genes.

    L Dumoutier;E Van Roost;G Ameye;L Michaux

  • Melanoma differentiation-associated gene 7/interleukin (IL)-24 is a novel ligand that regulates angiogenesis via the IL-22 receptor.

    Rajagopal Ramesh;Abner M. Mhashilkar;Fumihiro Tanaka;Yuji Saito

  • Cutting edge: IL-26 signals through a novel receptor complex composed of IL-20 receptor 1 and IL-10 receptor 2.

    Faruk Sheikh;Vitaliy V. Baurin;Anita Lewis-Antes;Nital K. Shah

  • Dual Role of IL-22 in Allergic Airway Inflammation and its Cross-talk with IL-17A.

    Anne-Gaelle Besnard;Robert Sabat;Laure Dumoutier;Jean-Christophe Renauld

  • Intestinal epithelial MyD88 is a sensor switching host metabolism towards obesity according to nutritional status

    Amandine Everard;Lucie Geurts;Robert Caesar;Matthias Van Hul

  • Interleukin-22 Is Produced by Invariant Natural Killer T Lymphocytes during Influenza A Virus Infection: POTENTIAL ROLE IN PROTECTION AGAINST LUNG EPITHELIAL DAMAGES*

    Christophe Paget;Stoyan Ivanov;Josette Fontaine;Joelle Renneson

  • The T-cell Lymphokine Interleukin-26 Targets Epithelial Cells through the Interleukin-20 Receptor 1 and Interleukin-10 Receptor 2 Chains

    Simon Hör;Simon Hör;Heide Pirzer;Laure Dumoutier;Finn Bauer

  • Cloning of a new type II cytokine receptor activating signal transducer and activator of transcription (STAT)1, STAT2 and STAT3.

    Laure Dumoutier;Diane Lejeune;Simon Hor;Helmut Fickenscher

Frequent Co-Authors

Jean-Christophe Renauld
Jean-Christophe Renauld Université Catholique de Louvain
Igor Polikarpov
Igor Polikarpov Universidade de São Paulo
Pierre Coulie
Pierre Coulie Université Catholique de Louvain
Bernhard Ryffel
Bernhard Ryffel University of Orléans
Jacques Van Snick
Jacques Van Snick Université Catholique de Louvain
Jean-Claude Sirard
Jean-Claude Sirard Institut Pasteur
Catherine Uyttenhove
Catherine Uyttenhove Ludwig Cancer Research
Mustapha Si-Tahar
Mustapha Si-Tahar François Rabelais University
Harry Sokol
Harry Sokol Sorbonne University
Ciriana Orabona
Ciriana Orabona University of Perugia

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