D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 96 Citations 37,153 407 World Ranking 491 National Ranking 14
Medicine D-index 96 Citations 37,464 421 World Ranking 5819 National Ranking 159

Overview

What is he best known for?

The fields of study he is best known for:

  • Immune system
  • Cytokine
  • Gene

Bernhard Ryffel mainly investigates Immunology, Inflammation, Tumor necrosis factor alpha, Immune system and Innate immune system. Immunology is represented through his Cytokine, Proinflammatory cytokine, Interleukin 22, Interleukin and Toll-like receptor research. His Inflammation study combines topics in areas such as Fibrosis, Interleukin 33, Adoptive cell transfer and Macrophage.

His Tumor necrosis factor alpha research is multidisciplinary, incorporating elements of Bronchoconstriction, Immunity, Interferon gamma and CD40. Bernhard Ryffel has included themes like Cytotoxic T cell, Gut flora and Myeloid-derived Suppressor Cell in his Immune system study. His study focuses on the intersection of Innate immune system and fields such as Acquired immune system with connections in the field of Mycobacterium tuberculosis.

His most cited work include:

  • Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors (1593 citations)
  • Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors (1199 citations)
  • The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide (912 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Immunology, Inflammation, Immune system, Tumor necrosis factor alpha and Receptor. His work deals with themes such as Tuberculosis and Mycobacterium tuberculosis, which intersect with Immunology. Bernhard Ryffel interconnects Fibrosis, Interleukin 33 and Lung in the investigation of issues within Inflammation.

Bernhard Ryffel combines subjects such as Cancer research, Microbiology and Virology with his study of Immune system. His Tumor necrosis factor alpha study integrates concerns from other disciplines, such as Mycobacterium bovis and Antibody. His Inflammasome study incorporates themes from Autophagy and Endocrinology.

He most often published in these fields:

  • Immunology (88.74%)
  • Inflammation (50.79%)
  • Immune system (29.25%)

What were the highlights of his more recent work (between 2016-2021)?

  • Inflammation (50.79%)
  • Immunology (88.74%)
  • Immune system (29.25%)

In recent papers he was focusing on the following fields of study:

Bernhard Ryffel focuses on Inflammation, Immunology, Immune system, Lung and Inflammasome. In general Inflammation, his work in Proinflammatory cytokine is often linked to Sting linking many areas of study. His research is interdisciplinary, bridging the disciplines of Mycobacterium tuberculosis and Immunology.

His research investigates the connection between Immune system and topics such as Microbiology that intersect with issues in Probiotic. His Lung research includes themes of COPD, Cancer research and Pathology. His Inflammasome research is multidisciplinary, relying on both Autophagy and Pharmacology.

Between 2016 and 2021, his most popular works were:

  • Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors (1593 citations)
  • Microbial metabolites control the thymic development of mucosal-associated invariant T cells (86 citations)
  • PD-1/PD-L1 pathway: an adaptive immune resistance mechanism to immunogenic chemotherapy in colorectal cancer. (84 citations)

In his most recent research, the most cited papers focused on:

  • Immune system
  • Gene
  • Cytokine

His primary scientific interests are in Inflammation, Immunology, Inflammasome, Cell biology and Immune system. The concepts of his Inflammation study are interwoven with issues in Tumor necrosis factor alpha, Innate immune system, Downregulation and upregulation and Autophagy. His Immunology study frequently draws connections to other fields, such as Signal transduction.

Bernhard Ryffel has researched Inflammasome in several fields, including Regulator and Endocrinology. He combines subjects such as Caspase-Independent Apoptosis, Orphan receptor, Antigen and Escherichia coli with his study of Cell biology. His studies deal with areas such as Pancreas, Regulatory macrophages and Microbiology as well as Immune system.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors

Bertrand Routy;Bertrand Routy;Bertrand Routy;Lisa Derosa;Lisa Derosa;Lisa Derosa;Connie P. M. Duong;Connie P. M. Duong.
Science (2018)

3021 Citations

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors

François Ghiringhelli;Lionel Apetoh;Antoine Tesniere;Antoine Tesniere;Antoine Tesniere;Laetitia Aymeric;Laetitia Aymeric;Laetitia Aymeric.
Nature Medicine (2009)

1721 Citations

The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide

Sophie Viaud;Sophie Viaud;Fabiana Saccheri;Grégoire Mignot;Takahiro Yamazaki.
Science (2013)

1549 Citations

Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells

Fanny Chalmin;Sylvain Ladoire;Grégoire Mignot;Julie Vincent.
Journal of Clinical Investigation (2010)

950 Citations

Alternating electric fields arrest cell proliferation in animal tumor models and human brain tumors

Eilon D. Kirson;Vladimír Dbalý;František Tovaryš;Josef Vymazal.
Proceedings of the National Academy of Sciences of the United States of America (2007)

823 Citations

CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands

Bruno Lamas;Mathias L Richard;Valentin Leducq;Hang-Phuong Pham.
Nature Medicine (2016)

818 Citations

Interleukin-17 is a negative regulator of established allergic asthma

Silvia Schnyder-Candrian;Dieudonnée Togbe;Isabelle Couillin;Isabelle Mercier.
Journal of Experimental Medicine (2006)

759 Citations

Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth

Mélanie Bruchard;Grégoire Mignot;Grégoire Mignot;Valentin Derangère;Valentin Derangère;Fanny Chalmin;Fanny Chalmin.
Nature Medicine (2013)

663 Citations

Antifibrotic and Anti-inflammatory Activity of the Tyrosine Kinase Inhibitor Nintedanib in Experimental Models of Lung Fibrosis

Lutz Wollin;Isabelle Maillet;Valérie Quesniaux;Alexander Holweg.
Journal of Pharmacology and Experimental Therapeutics (2014)

546 Citations

NOD2-mediated dysbiosis predisposes mice to transmissible colitis and colorectal cancer

Aurélie Couturier-Maillard;Thomas Secher;Ateequr Rehman;Sylvain Normand.
Journal of Clinical Investigation (2013)

542 Citations

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