World's Best Scientists 2026 revealed!
Bernhard Ryffel

Bernhard Ryffel

D-Index & Metrics

Immunology

D-Index
108
Citations
49768
World Ranking
529
National Ranking
14

Medicine

D-Index
108
Citations
49773
World Ranking
5940
National Ranking
171

Bernhard Ryffel publication distribution in Immunology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Immunology in 2026. The highlighted bar marks where Bernhard Ryffel sits on this spectrum.

62–71 publications: 9 scientists 72–81 publications: 23 scientists 82–91 publications: 40 scientists 92–101 publications: 72 scientists 102–111 publications: 86 scientists 112–121 publications: 108 scientists 122–131 publications: 150 scientists 132–141 publications: 160 scientists 142–151 publications: 159 scientists 152–161 publications: 189 scientists 162–171 publications: 166 scientists 172–181 publications: 181 scientists 182–191 publications: 188 scientists 192–201 publications: 187 scientists 202–211 publications: 178 scientists 212–221 publications: 158 scientists 222–231 publications: 168 scientists 232–241 publications: 159 scientists 242–251 publications: 160 scientists 252–261 publications: 148 scientists 262–271 publications: 116 scientists 272–281 publications: 125 scientists 282–291 publications: 115 scientists 292–301 publications: 111 scientists 302–311 publications: 95 scientists 312–321 publications: 97 scientists 322–331 publications: 97 scientists 332–341 publications: 99 scientists 342–351 publications: 96 scientists 352–361 publications: 68 scientists 362–371 publications: 76 scientists 372–381 publications: 71 scientists 382–391 publications: 71 scientists 392–401 publications: 62 scientists 402–411 publications: 54 scientists 412–421 publications: 41 scientists 422–431 publications: 63 scientists 432–441 publications: 53 scientists 442–451 publications: 31 scientists 452–461 publications: 42 scientists 462–471 publications: 40 scientists 472–481 publications: 29 scientists 482–491 publications: 34 scientists 492–501 publications: 30 scientists 502–511 publications: 23 scientists 512–521 publications: 41 scientists 522–531 publications: 29 scientists 532–541 publications: 28 scientists 542–551 publications: 16 scientists 552–561 publications: 18 scientists 562–571 publications: 18 scientists 572–581 publications: 17 scientists 582–591 publications: 17 scientists 592–601 publications: 17 scientists 602–611 publications: 19 scientists 612–621 publications: 13 scientists 622–631 publications: 12 scientists 632–641 publications: 11 scientists 642–651 publications: 16 scientists 652–661 publications: 9 scientists 662–671 publications: 5 scientists 672–681 publications: 13 scientists 682–691 publications: 12 scientists 692–701 publications: 6 scientists 702–711 publications: 6 scientists 712–721 publications: 9 scientists 722–731 publications: 9 scientists 732–741 publications: 6 scientists 742–751 publications: 11 scientists 752–761 publications: 10 scientists 762–771 publications: 7 scientists 772–781 publications: 12 scientists 782–791 publications: 7 scientists 792–801 publications: 5 scientists 802–806 publications: 1 scientists 807+ publications: 100 scientists
62 publications 807+

This scientist: 422 publications — 83rd percentile

83% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 807 publications or more.

Bernhard Ryffel D-index placement in Immunology in 2026

The chart shows the D-index (discipline H-index) distribution of Immunology scientists ranked by Research.com in 2026. The highlighted bar marks where Bernhard Ryffel sits on this spectrum.

40–41 D-Index: 28 scientists 42–43 D-Index: 91 scientists 44–45 D-Index: 157 scientists 46–47 D-Index: 192 scientists 48–49 D-Index: 175 scientists 50–51 D-Index: 188 scientists 52–53 D-Index: 177 scientists 54–55 D-Index: 155 scientists 56–57 D-Index: 194 scientists 58–59 D-Index: 201 scientists 60–61 D-Index: 197 scientists 62–63 D-Index: 201 scientists 64–65 D-Index: 173 scientists 66–67 D-Index: 167 scientists 68–69 D-Index: 172 scientists 70–71 D-Index: 199 scientists 72–73 D-Index: 184 scientists 74–75 D-Index: 133 scientists 76–77 D-Index: 162 scientists 78–79 D-Index: 127 scientists 80–81 D-Index: 121 scientists 82–83 D-Index: 125 scientists 84–85 D-Index: 121 scientists 86–87 D-Index: 102 scientists 88–89 D-Index: 96 scientists 90–91 D-Index: 75 scientists 92–93 D-Index: 72 scientists 94–95 D-Index: 74 scientists 96–97 D-Index: 66 scientists 98–99 D-Index: 68 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 60 scientists 104–105 D-Index: 54 scientists 106–107 D-Index: 36 scientists 108–109 D-Index: 23 scientists 110–111 D-Index: 52 scientists 112–113 D-Index: 41 scientists 114–115 D-Index: 34 scientists 116–117 D-Index: 25 scientists 118–119 D-Index: 28 scientists 120–121 D-Index: 11 scientists 122–123 D-Index: 20 scientists 124–125 D-Index: 27 scientists 126–127 D-Index: 19 scientists 128–129 D-Index: 20 scientists 130–131 D-Index: 16 scientists 132–133 D-Index: 17 scientists 134–135 D-Index: 14 scientists 136–137 D-Index: 15 scientists 138–139 D-Index: 9 scientists 140–141 D-Index: 11 scientists 142–143 D-Index: 9 scientists 144–145 D-Index: 9 scientists 146–147 D-Index: 7 scientists 148–149 D-Index: 7 scientists 150–151 D-Index: 7 scientists 152–153 D-Index: 5 scientists 154–155 D-Index: 8 scientists 156 D-Index: 6 scientists 157+ D-Index: 96 scientists
40 D-Index 157+

This scientist: 108 D-Index — 89th percentile

89% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 157 D-Index or more.

Overview

Bernhard Ryffel is affiliated with the University of Orléans in France. The research focus spans multiple fields including Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology. Their work covers several subfields such as Immunology, Molecular Biology, Pulmonary and Respiratory Medicine, Physiology, and Surgery.

The scientist has contributed extensively to topics related to inflammasome and immune disorders, IL-33, ST2, and ILC pathways, immune response and inflammation, immune cell function and interaction, interstitial lung diseases and idiopathic pulmonary fibrosis, interferon and immune responses, and asthma and respiratory diseases.

Bernhard Ryffel's publication record includes frequent contributions to several key venues, notably Frontiers in Immunology with 14 publications, Revue des Maladies Respiratoires with 5, bioRxiv (Cold Spring Harbor Laboratory) with 4, Nature Communications with 3, and Scientific Reports with 3 papers.

Recent papers authored or co-authored by Ryffel include:

  • Ketogenic diet and ketone bodies enhance the anticancer effects of PD-1 blockade (2020, JCI Insight)
  • Oxidative Stress in Ozone-Induced Chronic Lung Inflammation and Emphysema: A Facet of Chronic Obstructive Pulmonary Disease (2020, Frontiers in Immunology)
  • STING agonist diABZI induces PANoptosis and DNA mediated acute respiratory distress syndrome (ARDS) (2022, Cell Death and Disease)
  • The commensal skin microbiota triggers type I IFN-dependent innate repair responses in injured skin (2020, Nature Immunology)
  • Inhibition of the NLRP3 inflammasome prevents ovarian aging (2021, Science Advances)

Frequent collaborators in research include Valérie Quesniaux, Dieudonnée Togbe, Isabelle Couillin, Marc Le Bert, and Florence Savigny.

Best Publications

  • Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors

    Bertrand Routy;Bertrand Routy;Bertrand Routy;Lisa Derosa;Lisa Derosa;Lisa Derosa;Connie P. M. Duong;Connie P. M. Duong

  • The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide

    Sophie Viaud;Sophie Viaud;Fabiana Saccheri;Grégoire Mignot;Takahiro Yamazaki

  • Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors

    François Ghiringhelli;Lionel Apetoh;Antoine Tesniere;Antoine Tesniere;Antoine Tesniere;Laetitia Aymeric;Laetitia Aymeric;Laetitia Aymeric

  • CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands

    Bruno Lamas;Mathias L Richard;Valentin Leducq;Hang-Phuong Pham

  • Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells

    Fanny Chalmin;Sylvain Ladoire;Grégoire Mignot;Julie Vincent

  • Alternating electric fields arrest cell proliferation in animal tumor models and human brain tumors

    Eilon D. Kirson;Vladimír Dbalý;František Tovaryš;Josef Vymazal

  • Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth

    Mélanie Bruchard;Grégoire Mignot;Grégoire Mignot;Valentin Derangère;Valentin Derangère;Fanny Chalmin;Fanny Chalmin

  • Interleukin-17 is a negative regulator of established allergic asthma

    Silvia Schnyder-Candrian;Dieudonnée Togbe;Isabelle Couillin;Isabelle Mercier

  • Antifibrotic and Anti-inflammatory Activity of the Tyrosine Kinase Inhibitor Nintedanib in Experimental Models of Lung Fibrosis

    Lutz Wollin;Isabelle Maillet;Valérie Quesniaux;Alexander Holweg

  • NOD2-mediated dysbiosis predisposes mice to transmissible colitis and colorectal cancer

    Aurélie Couturier-Maillard;Thomas Secher;Ateequr Rehman;Sylvain Normand

  • Caloric Restriction Mimetics Enhance Anticancer Immunosurveillance

    Federico Pietrocola;Federico Pietrocola;Jonathan Pol;Erika Vacchelli;Erika Vacchelli;Shuan Rao

  • IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice

    Pamela Gasse;Caroline Mary;Isabelle Guenon;Nicolas Noulin

  • Toll-Like Receptor 4 Expression Is Required to Control Chronic Mycobacterium tuberculosis Infection in Mice

    Brian Abel;Nathalie Thieblemont;Nathalie Thieblemont;Valerie J. F. Quesniaux;Najmeeyah Brown

  • Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis.

    Pamela Gasse;Nicolas Riteau;Sabine Charron;Sandra Girre

  • Extracellular ATP is a danger signal activating P2X7 receptor in lung inflammation and fibrosis.

    Nicolas Riteau;Pamela Gasse;Louis Fauconnier;Aurélie Gombault

  • Toll-like receptor 2-deficient mice succumb to Mycobacterium tuberculosis infection.

    Michael B. Drennan;Delphine Nicolle;Valerie J.F. Quesniaux;Muazzam Jacobs

  • NK cell activation by dendritic cells (DCs) requires the formation of a synapse leading to IL-12 polarization in DCs

    Christophe Borg;Abdelali Jalil;Diego Laderach;Kouji Maruyama

  • IL-18 induces PD-1-dependent immunosuppression in cancer.

    Magali Terme;Evelyn Ullrich;Laetitia Aymeric;Kathrin Meinhardt

  • Ketogenic diet and ketone bodies enhance the anticancer effects of PD-1 blockade

    Gladys Ferrere;Maryam Tidjani Alou;Peng Liu;Anne-Gaëlle Goubet

  • Oxeiptosis, a ROS-induced caspase-independent apoptosis-like cell-death pathway.

    Cathleen Holze;Chloé Michaudel;Claire Mackowiak;Darya A. Haas

  • Fatal Mycobacterium tuberculosis infection despite adaptive immune response in the absence of MyD88.

    Cecile M. Fremond;Vladimir Yeremeev;Delphine M. Nicolle;Muazzam Jacobs

  • Distinct and Nonredundant In Vivo Functions of TNF Produced by T Cells and Macrophages/Neutrophils: Protective and Deleterious Effects

    Sergei I. Grivennikov;Alexei V. Tumanov;Alexei V. Tumanov;Dmitry J. Liepinsh;Andrei A. Kruglov

Frequent Co-Authors

Valérie F. J. Quesniaux
Valérie F. J. Quesniaux University of Orléans
Song Guo Zheng
Song Guo Zheng Shanghai Jiao Tong University
Lionel Apetoh
Lionel Apetoh Indiana University
François Ghiringhelli
François Ghiringhelli Centre Georges François Leclerc
Shizuo Akira
Shizuo Akira Osaka University
Sergei A. Nedospasov
Sergei A. Nedospasov Lomonosov Moscow State University
Mathias Chamaillard
Mathias Chamaillard University of Lille
David D. Brand
David D. Brand University of Tennessee Health Science Center
Fernando Q. Cunha
Fernando Q. Cunha Universidade de São Paulo
Laurence Zitvogel
Laurence Zitvogel University of Paris-Saclay

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