Samuel Singer focuses on Cancer research, Sarcoma, Pathology, Internal medicine and Gastrointestinal stromal tumors. His Cancer research research is multidisciplinary, incorporating perspectives in Mutation, Cancer and Receptor tyrosine kinase. His Sarcoma research is multidisciplinary, relying on both Survival analysis and Soft tissue.
His Internal medicine research integrates issues from Endocrinology and Oncology. His research in Oncology intersects with topics in Sunitinib malate, Tolerability and Surgery. His work focuses on many connections between Gastrointestinal stromal tumors and other disciplines, such as Tyrosine phosphorylation, that overlap with his field of interest in Carcinogenesis.
His scientific interests lie mostly in Cancer research, Sarcoma, Internal medicine, Surgery and Pathology. His Cancer research research includes elements of Mutation, Gene and Receptor tyrosine kinase. Samuel Singer has researched Sarcoma in several fields, including Survival analysis, Metastasis and Radiation therapy.
His Internal medicine study combines topics in areas such as Gastroenterology, Endocrinology and Oncology. Samuel Singer has included themes like Fusion gene and Fluorescence in situ hybridization in his Pathology study. His GiST research is multidisciplinary, incorporating elements of Tyrosine kinase, Stromal tumor and Imatinib mesylate.
Cancer research, Internal medicine, Oncology, Sarcoma and Gene are his primary areas of study. His studies in Cancer research integrate themes in fields like Undifferentiated Pleomorphic Sarcoma, Downregulation and upregulation, microRNA, Myxofibrosarcoma and Regulation of gene expression. In general Internal medicine study, his work on GiST, Combination therapy and Progression-free survival often relates to the realm of In patient, thereby connecting several areas of interest.
His Oncology research also works with subjects such as
Samuel Singer mainly investigates Cancer research, Sarcoma, Internal medicine, Oncology and Surgery. He interconnects DNA methylation, Chromatin, microRNA, Signal transduction and Regulation of gene expression in the investigation of issues within Cancer research. Sarcoma is a subfield of Pathology that Samuel Singer investigates.
When carried out as part of a general Pathology research project, his work on Soft tissue is frequently linked to work in CD99, therefore connecting diverse disciplines of study. In the subject of general Surgery, his work in Prospective cohort study is often linked to Solitary fibrous tumor, thereby combining diverse domains of study. His Fusion gene research includes elements of Mutation and Immunohistochemistry.
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Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors.
George Daniel Demetri;Margaret von Mehren;Charles D. Blanke;Annick Diane Van Den Abbeele.
The New England Journal of Medicine (2002)
The landscape of somatic copy-number alteration across human cancers
Rameen Beroukhim;Craig H. Mermel;Craig H. Mermel;Dale Porter;Guo Wei.
PDGFRA Activating Mutations in Gastrointestinal Stromal Tumors
Michael C. Heinrich;Christopher L. Corless;Anette Duensing;Laura McGreevey.
Kinase Mutations and Imatinib Response in Patients With Metastatic Gastrointestinal Stromal Tumor
Michael C. Heinrich;Christopher L. Corless;George D. Demetri;Charles D. Blanke.
Journal of Clinical Oncology (2003)
Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.
Katherine A. Hoadley;Christina Yau;Christina Yau;Toshinori Hinoue;Denise M. Wolf.
Pan-cancer analysis of whole genomes
Peter J. Campbell;Gad Getz;Jan O. Korbel;Joshua M. Stuart.
Differentiation and reversal of malignant changes in colon cancer through PPARgamma.
Pasha Sarraf;Elisabetta Mueller;Daniel Jones;Frederick J. King.
Nature Medicine (1998)
KIT activation is a ubiquitous feature of gastrointestinal stromal tumors.
Brian P. Rubin;Samuel Singer;Connie Tsao;Anette Duensing.
Cancer Research (2001)
Terminal Differentiation of Human Breast Cancer through PPARγ
Elisabetta Mueller;Pasha Sarraf;Peter Tontonoz;Peter Tontonoz;Ronald M. Evans;Ronald M. Evans.
Molecular Cell (1998)
Acquired Resistance to Imatinib in Gastrointestinal Stromal Tumor Occurs Through Secondary Gene Mutation
Cristina R. Antonescu;Peter Besmer;Tianhua Guo;Knarik Arkun.
Clinical Cancer Research (2005)
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