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Biology and Biochemistry

D-Index
101
Citations
53922
World Ranking
1417
National Ranking
808

Overview

Nicholas D. Socci is affiliated with Memorial Sloan Kettering Cancer Center in the United States. Their research primarily focuses on the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with notable subfields in Molecular Biology, Oncology, Immunology, Cancer Research, and Pulmonary and Respiratory Medicine.

The main topics covered in their work include:

  • Cancer Genomics and Diagnostics
  • Sarcoma Diagnosis and Treatment
  • Cancer Immunotherapy and Biomarkers
  • Immunotherapy and Immune Responses
  • Immune Cell Function and Interaction
  • Epigenetics and DNA Methylation
  • T-cell and B-cell Immunology

Recent papers by Nicholas D. Socci demonstrate an active engagement with cancer biology, immunology, and stem cell research. Significant publications include:

  • "An autoimmune stem-like CD8 T cell population drives type 1 diabetes" (2021, Nature)
  • "Ordered and deterministic cancer genome evolution after p53 loss" (2022, Nature)
  • "Biphasic Activation of WNT Signaling Facilitates the Derivation of Midbrain Dopamine Neurons from hESCs for Translational Use" (2021, Cell stem cell)
  • "Clinical sequencing of soft tissue and bone sarcomas delineates diverse genomic landscapes and potential therapeutic targets" (2022, Nature Communications)
  • "TCR signal strength defines distinct mechanisms of T cell dysfunction and cancer evasion" (2021, The Journal of Experimental Medicine)

These papers reflect research attention on T cell biology, cancer genomics, immune dysfunction, and stem cell differentiation relevant to translational applications.

Key frequent coauthors in Socci's collaborations include:

  • David B. Solit
  • Agnès Viale
  • Christine A. Iacobuzio-Donahue
  • Ingo K. Mellinghoff
  • Michael F. Berger

Frequent publication venues indicate an emphasis on cancer and biomedical research, such as:

  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Clinical Cancer Research
  • Nature Communications
  • Nature

Best Publications

  • Comprehensive genomic characterization defines human glioblastoma genes and core pathways

    Roger McLendon;Allan Friedman;Darrell Bigner;Erwin G. Van Meir

  • A mammalian microRNA expression atlas based on small RNA library sequencing.

    Pablo Landgraf;Mirabela Rusu;Robert Sheridan;Alain Sewer;Alain Sewer

  • Integrative genomic profiling of human prostate cancer

    Barry S. Taylor;Nikolaus Schultz;Haley Hieronymus;Anuradha Gopalan

  • Comprehensive genomic characterization of squamous cell lung cancers

    Peter S. Hammerman;Doug Voet;Michael S. Lawrence;Douglas Voet

  • Funnels, pathways, and the energy landscape of protein folding: A synthesis

    Joseph D. Bryngelson;José Nelson Onuchic;Nicholas D. Socci;Peter G. Wolynes

  • Pan-cancer analysis of whole genomes

    Peter J. Campbell;Gad Getz;Jan O. Korbel;Joshua M. Stuart

  • Prognostic relevance of integrated genetic profiling in acute myeloid leukemia

    Jay P. Patel;Mithat Gönen;Maria E. Figueroa;Hugo Fernandez

  • Molecular Determinants of Response to Anti-Programmed Cell Death (PD)-1 and Anti-Programmed Death-Ligand 1 (PD-L1) Blockade in Patients With Non-Small-Cell Lung Cancer Profiled With Targeted Next-Generation Sequencing.

    Hira Rizvi;Francisco Sanchez-Vega;Konnor La;Walid Chatila

  • Intestinal Domination and the Risk of Bacteremia in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

    Ying Taur;Joao B. Xavier;Lauren Lipuma;Carles Ubeda

  • Vancomycin-resistant Enterococcus domination of intestinal microbiota is enabled by antibiotic treatment in mice and precedes bloodstream invasion in humans

    Carles Ubeda;Ying Taur;Robert R. Jenq;Michele J. Equinda

  • Comprehensive and Integrated Genomic Characterization of Adult Soft Tissue Sarcomas

    Adam Abeshouse;Clement Adebamowo;Sally N. Adebamowo;Rehan Akbani

  • Role for Stearoyl-CoA Desaturase-1 in Leptin-Mediated Weight Loss

    Paul Cohen;Makoto Miyazaki;Nicholas D. Socci;Aaron Hagge-Greenberg

  • Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis

    Lambert Busque;Jay P Patel;Maria E Figueroa;Aparna Vasanthakumar

  • Comprehensive evaluation of differential gene expression analysis methods for RNA-seq data

    Franck Rapaport;Raya Khanin;Yupu Liang;Mono Pirun

  • Human ES cell-derived neural rosettes reveal a functionally distinct early neural stem cell stage

    Yechiel Elkabetz;Georgia Panagiotakos;George Al Shamy;Nicholas D. Socci

  • Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy.

    Jordi Barretina;Barry S Taylor;Barry S Taylor;Shantanu Banerji;Shantanu Banerji;Alexis H Ramos;Alexis H Ramos

  • Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity

    Matthew T Chang;Saurabh Asthana;Sizhi Paul Gao;Byron H Lee

  • Defining Molecular Profiles of Poor Outcome in Patients With Invasive Bladder Cancer Using Oligonucleotide Microarrays

    Marta Sanchez-Carbayo;Nicholas D. Socci;Juanjo Lozano;Fabien Saint

  • Constitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require full-length androgen receptor

    Philip A. Watson;Yinan F. Chen;Minna D. Balbas;John Wongvipat

  • Germline mutations in BAP1 predispose to melanocytic tumors

    Thomas Wiesner;Anna C Obenauf;Anna C Obenauf;Rajmohan Murali;Isabella Fried

Frequent Co-Authors

Agnes Viale
Agnes Viale Memorial Sloan Kettering Cancer Center
Samuel Singer
Samuel Singer Memorial Sloan Kettering Cancer Center
Barry S. Taylor
Barry S. Taylor Memorial Sloan Kettering Cancer Center
Michael F. Berger
Michael F. Berger Memorial Sloan Kettering Cancer Center
David B. Solit
David B. Solit Memorial Sloan Kettering Cancer Center
Cristina R. Antonescu
Cristina R. Antonescu Memorial Sloan Kettering Cancer Center
Nikolaus Schultz
Nikolaus Schultz Memorial Sloan Kettering Cancer Center
Chris Sander
Chris Sander Harvard University
Marc Ladanyi
Marc Ladanyi Memorial Sloan Kettering Cancer Center
José N. Onuchic
José N. Onuchic Rice University

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